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Netherlands-based Synthesis are proud to offer the first “immersive psychedelic transformation program” with their Synthesis Expansion retreat.

The 7-week program involves three weeks of in-depth preparation with experts and facilitators, two transformative mushroom ceremonies, and another three weeks of integration with fellow participants and Synthesis experts.

Preparation and integration sessions take place remotely, while the ceremonies themselves are held at the Synthesis Venwoude location.

The clinic also partners with the Psychedelic Research Group of Imperial College London to provide data and better understanding of this revered and remarkable plant medicine. Lead facilitator Daan Keiman is also the co-founder of Guild of Guides Netherlands, a group of professional “psychedelic sitters”.

Along with the psilocybin experiences, the Synthesis Expansion retreat provides a range of other wellness activities, including bodywork, meditation, soundwork, and psychedelic education.

Psilocybin Treatments Offered

  • Mushrooms

Important Info

  • Synthesis is not equipped to offer psychedelic therapy at this time.
  • Although based in Amsterdam, Synthesis retreat locations are outside of the city.
  • Synthesis Expansion is currently unable to provide retreats to individuals using anti-depressants.
  • The Synthesis Expansion retreat is held at the Venwoude location.
  • Due to COVID-19 concerns and protocol


Synthesis Expansion is an immersive psychedelic experience designed to promote “deep and lasting transformation”. The retreat begins with a preliminary call to Synthesis.

During this discussion any medical concerns will be addressed. Along with truffle experiences, each retreat also focuses on ways to improve mood, focus, and states of consciousness in one’s daily life.

What You Need to Know About Magic Mushrooms

Magic mushrooms are psychedelic because they contain the psychedelic compounds psilocybin and psilocin. They are also a completely natural psychedelic. Psilocybin is a prodrug, meaning it is only psychoactive when consumed and processed in the body.

When taking mushrooms containing psilocybin, the body will convert the psilocybin into psilocin, which is psychoactive. Both psilocybin and psilocin belong to a group of chemicals known as tryptamines. This grouping also includes compounds like DMT and 5-MeO-DMT.

Magic mushroom use is thousands of years old, but the idea largely entered public awareness with the publication of an article about magic mushrooms in Life magazine in 1957. Written by the then vice-president of J.P. Morgan R. Gordon Wasson, this article detailed a magic mushroom ceremony in Oaxaca, Mexico that Wasson took part in.

In the decade that followed, more Westerners began experimenting with psilocybin mushrooms.

Today, promising new research trials have found that psilocybin can effectively treat a number of intransigent psychiatric conditions. It’s why psychedelics for depression and other mental health issues are becoming more popular these days.

Discover more Psychedelics Retreats and Ketamine Clinics in Europe


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