✓ Last verified: March 3, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Advanced TMS Center in Ladera Ranch, California offers ketamine therapy alongside transcranial magnetic stimulation (TMS) in southern Orange County. Their multi-modality approach to treatment-resistant mental health conditions provides patients with multiple evidence-based options, combining cutting-edge neurostimulation with ketamine protocols in a modern clinical environment.
Review Scores
4.9 stars
Location
Ladera Ranch, California
Address
333 Corporate Dr., Suite 260, Ladera Ranch, CA 92694
Accepts insurance for TMS; contact for ketamine coverage
KAP Available?
Contact for details
Clinical Lead
Advanced TMS Center Medical Team
HealingMaps Take: Advanced TMS Center offers a compelling combination of ketamine and TMS therapies in the affluent Ladera Ranch area of south Orange County. Having both treatment modalities available under one roof allows clinicians to tailor or combine approaches based on individual patient response. Their location serves a wide catchment area including Mission Viejo, San Juan Capistrano, and the broader south OC community.
Market Position: Advanced TMS Center is a verified ketamine provider in the Ranch metro on HealingMaps — one of 1,473 clinics we have mapped and tracked across 3,142 U.S. counties.
Is Advanced TMS Center Right for You?
✓ Choose Advanced TMS Center if:
You want a multi-protocol practice (Spravato + IV ketamine) where you can switch between modalities without changing providers
You want commercial-insurance-covered Spravato (esketamine) for treatment-resistant depression
You want comprehensive interventional psychiatry combining ketamine with TMS (transcranial magnetic stimulation)
You're treating chronic pain (CRPS, fibromyalgia, neuropathy) and want IV ketamine protocols
✗ Look elsewhere if:
You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy (this clinic uses the medical model)
Advanced TMS Center Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$525–$900
Range: $450–$1,500/session
Estimated total program
$3,150–$5,400
Range: $2,700–$9,000/6-session series
Your estimate vs. national patient-reported medianBased on national tracking, adjusted for Los Angeles, CA market
Select a treatment type to see pricing context.
Get matched to verified clinics
A HealingMaps specialist will follow up within one business day with providers that match your estimate, protocol, and insurance situation.
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A HealingMaps specialist will reach out within one business day with clinic matches based on your estimate. In the meantime, review the verified providers below.
Ketamine Protocols Compared — What’s Offered at Advanced TMS Center
Industry pricing reference. Advanced TMS Center has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
Protocol
Typical Industry Cost
Offered Here
IV Ketamine Infusion
$350–$650/session
✓
Spravato (esketamine)
$0–$250 copay (insured)
✓
TMS (transcranial magnetic stimulation)
$200–$300/session, often insurance-covered
✓
IM Ketamine
$250–$400/injection
—
KAP (with integrated talk therapy)
$400–$1,200/session
—
At-home oral troches
$150–$300/month
—
What to Expect at Your First Advanced TMS Center Appointment
Initial intake call — Medical history review and clinical eligibility check.
Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Advanced TMS Center clinical team.
First treatment session — supervised ketamine therapy session in a private treatment room, lasting approximately 60–90 minutes. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your ketamine session.
What to Ask on Your Advanced TMS Center Consult Call
How long has the Advanced TMS Center clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
What’s a typical 6-session total cost at Advanced TMS Center, and do you offer payment plans, HSA/FSA-eligible billing, or sliding-scale pricing?
California’s psychedelic-therapy regulatory landscape is evolving — do you stay current with state Department of Public Health and Medical Board guidance on ketamine prescribing?
What does Advanced TMS Center recommend for patients who don’t respond to the standard 6-session acute series?
Patient Questions about Advanced TMS Center
This 5-question summary is matched to the protocols and conditions Advanced TMS Center treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
What ketamine protocols does Advanced TMS Center offer?
Advanced TMS Center offers Spravato and IV ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.
Does Advanced TMS Center offer Spravato (esketamine)?
Yes — Advanced TMS Center offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.
Is Advanced TMS Center suited for treatment-resistant depression?
Advanced TMS Center treats depression via Spravato (FDA-cleared for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Does Advanced TMS Center treat PTSD?
Yes — Advanced TMS Center treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Can Advanced TMS Center help with anxiety disorders?
Yes — Advanced TMS Center treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
TMS therapy is also available at this clinic, alongside ketamine and Spravato. Unlike cash-pay ketamine, TMS is covered by most major insurance plans for treatment-resistant depression. TMS is FDA-cleared for treatment-resistant depression (since 2008), OCD via Deep TMS, anxious depression, and adolescent MDD ages 15–21. Read our complete guide to TMS therapy for FDA-cleared conditions, device differences, insurance coverage by carrier, and what to expect at your first appointment. Browse verified TMS clinics in our directory.
The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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