Crestline Health and Wellness – Birmingham, Alabama Ketamine Clinics, Spravato Clinics

✓ Last verified: January 15, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Crestline Health and Wellness was founded in 2019 by Dr. Amy van Elkan, a board-certified anesthesiologist with extensive experience administering ketamine. As one of the first dedicated ketamine clinics in the Birmingham area, the practice focuses exclusively on ketamine infusion therapy and Spravato (intranasal esketamine) for mood disorders and chronic pain conditions.

HealingMaps Take: Crestline Health and Wellness brings strong clinical credentials to ketamine therapy in the Birmingham area. Dr. Amy van Elkan’s background in anesthesiology means patients are in the hands of a physician with deep experience administering ketamine safely. The clinic’s dual offering of IV ketamine and Spravato provides flexibility—Spravato may be insurance-eligible for some patients, making treatment more accessible. The practice’s exclusive focus on ketamine therapy, rather than offering it as a side service, signals a high level of specialization.

Market Position: Crestline Health and Wellness is a Spravato-certified clinic in the Birmingham metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.

Crestline Health and Wellness Ketamine Cost Calculator

Ketamine Protocols Compared — What’s Offered at Crestline Health and Wellness

Industry pricing reference. Crestline Health and Wellness has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

What to Expect at Your First Crestline Health and Wellness Appointment

1. Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Call (205) 848-2768 or visit crestlinehealthandwellness.com to schedule.
2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Crestline Health and Wellness clinical team.
3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 300 Office Park Drive, Suite 105, Mountain Brook, AL 35223. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your Crestline Health and Wellness Consult Call

• How long has the Crestline Health and Wellness clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
• Walk me through Crestline Health and Wellness’s Spravato prior authorization process versus your IV ketamine cash-pay or superbill workflow — which is the better fit for my insurance situation?
• What does Crestline Health and Wellness recommend for patients who don’t respond to the standard 6-session acute series?

Birmingham Ketamine Market Snapshot

Sources: CDC PLACES 2023 (Jefferson County, AL, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.

• Adult depression in Jefferson County, AL: 22.7%
• Frequent mental distress (14+ days per month): 17.5%
• Adults lacking health insurance: 9.1%
• Jefferson County population: 672,265 · median household income $63,595
• Recent Birmingham-area inquiries to HealingMaps: A growing stream of Alabama residents have recently contacted us seeking ketamine care

Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.

From the 2026 Ketamine Industry Report

For patients whose HSA or FSA funds are insufficient, third-party medical financing programs like CareCredit are accepted at a growing share of ketamine clinics — typically offering 6 to 24-month deferred-interest plans on the full acute-series cost of $2,100–$3,000. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.

Patient Questions about Crestline Health and Wellness

This 6-question summary is matched to the protocols and conditions Crestline Health and Wellness treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

What ketamine protocols does Crestline Health and Wellness offer?

Crestline Health and Wellness offers Spravato and IV ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.

Does Crestline Health and Wellness offer Spravato (esketamine)?

Yes — Crestline Health and Wellness offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.

Is Crestline Health and Wellness suited for treatment-resistant depression?

Crestline Health and Wellness treats depression via Spravato (FDA-approved for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Crestline Health and Wellness treat chronic pain conditions?

Yes — Crestline Health and Wellness treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does Crestline Health and Wellness treat PTSD?

Yes — Crestline Health and Wellness treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Crestline Health and Wellness help with anxiety disorders?

Yes — Crestline Health and Wellness treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

View all REMS-certified Spravato clinics in Alabama and across the United States.

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Review (1)

• 
  Kelly Griffith

  June 13, 2022 at 7:10 pm

  Multiple chronic illnesses dx recently

  Have had no consistent mental health care

  Consider myself currently in a crisis, but Er is not an option due to medical related ptsd
  Dx anxiety depression cptsd adhd cognitive impairment working memory lowered iq

  Helpful Review