✓ Last verified: February 8, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: High Country Infusion and Wellness is the first and only ketamine infusion clinic in Colorado’s high country, serving Summit County and the surrounding mountain communities from Main Street in Frisco. The clinic is run by Mandy, a board-certified Nurse Anesthetist (CRNA) with over 14 years of experience administering ketamine in emergency rooms, ICUs, operating rooms, and outpatient settings. In addition to ketamine therapy, the clinic offers IV vitamin and hydration infusions.
| Review Scores | ⭐ Highly rated (13 reviews on BestPros) |
| Location | Frisco, Colorado (Summit County) |
| Address | 409 Main St, Suite 216, Frisco, CO 80443 |
| Phone | (970) 446-5191 |
| Website | highcountryinfusion.com |
| Treatments | IV Ketamine Infusions, IV Vitamin & Hydration Therapy |
| Conditions Treated | Depression, Anxiety, PTSD, Addiction, Chronic Pain, Migraines |
| Cost | Contact clinic for pricing |
| Insurance | Contact clinic for details |
| KAP Available? | No |
| Clinical Lead | Mandy, CRNA (14+ years experience) |
💡 No clinic-specific pricing posted? See our ketamine therapy cost guide for typical pricing ranges by treatment type and insurance pathways.
HealingMaps Take: High Country Infusion fills a critical gap for mountain community residents who would otherwise face a long drive to Denver or Colorado Springs for ketamine therapy. Having a board-certified nurse anesthetist with 14+ years of ketamine experience running the clinic provides excellent safety credentials. Patients consistently praise the comfortable, private treatment rooms and Mandy’s dedicated, compassionate approach—with some reporting meaningful improvement after just three sessions. The Frisco Main Street location makes it accessible for residents of Breckenridge, Silverthorne, Dillon, and the broader Summit County area.
Market Position: High Country Infusion and Wellness treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.
Industry pricing reference. High Country Infusion and Wellness has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine Infusion | $350–$650/session | ✓ |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with integrated talk therapy) | $400–$1,200/session | — |
| At-home oral troches | $150–$300/month | — |
Sources: CDC PLACES 2023 (Summit County, CO, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
The majority of ketamine patients moving from acute to maintenance phase report monthly maintenance sessions as the typical long-term cadence — balancing clinical efficacy with affordability. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
This 4-question summary is matched to the protocols and conditions High Country Infusion and Wellness treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
High Country Infusion and Wellness treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — High Country Infusion and Wellness treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — High Country Infusion and Wellness treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Yes — High Country Infusion and Wellness treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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