✓ Last verified: April 4, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Midwest Institute for Hearts and Minds is the longest-running ketamine clinic in St. Louis, with over 1,500 infusions administered and an 85% success rate. Their team brings more than 50 years’ combined experience in treating the most difficult cases. The standard protocol is six 40-minute infusions over three weeks.
| Google Reviews | ⭐ Highly rated (85% success rate, 1,500+ infusions) |
| Location | St. Louis, Missouri |
| Address | 9701 Landmark Parkway Drive, Suite 110, St. Louis, MO 63127 |
| Phone | (314) 270-4248 |
| Website | midwestheartsandminds.com |
| Treatments | IV Ketamine Infusions |
| Conditions Treated | Depression, Anxiety, PTSD, CRPS, Chronic Pain |
| Cost | Contact clinic for pricing |
| Insurance | Contact clinic for details |
| KAP Available | Not specified |
| Clinical Lead | 50+ years combined clinical experience |
HealingMaps Take: As St. Louis’s longest-running ketamine clinic with an 85% success rate across 1,500+ infusions, Midwest Institute for Hearts and Minds has the track record to back their claims. Patients report drastic, immediate mood improvements—some after just one visit. The team’s 50+ years of combined experience treating complex cases inspires confidence. The top recommendation for St. Louis-area patients seeking proven ketamine therapy.
Market Position: Midwest Institute for Hearts and Minds is an IV-ketamine-focused clinic in the Louis metro — the most common cash-pay protocol in the HealingMaps verified directory.
Industry pricing reference. Midwest Institute for Hearts and Minds has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
This 4-question summary is matched to the protocols and conditions Midwest Institute for Hearts and Minds treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Midwest Institute for Hearts and Minds treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Midwest Institute for Hearts and Minds treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — Midwest Institute for Hearts and Minds treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Yes — Midwest Institute for Hearts and Minds treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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