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✓ Last verified: January 31, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Yale New Haven Psychiatric Hospital in New Haven, Connecticut logo

Known For: Yale New Haven Psychiatric Hospital houses one of the most historically significant ketamine therapy programs in the world. Yale researchers were the first to discover in the late 1990s that ketamine provided rapid relief for treatment-resistant depression, and their Interventional Psychiatric Program now treats 20–30 patients weekly. The hospital offers both IV ketamine infusions and Spravato® (esketamine) nasal spray, backed by decades of clinical research and the full resources of a major academic medical center.

Google Reviews⭐ Academic Medical Center – Yale-affiliated
LocationNew Haven, Connecticut
Address184 Liberty Street, New Haven, CT 06519
Phone(203) 688-9704
Websiteynhh.org
TreatmentsIV Ketamine Infusions, Spravato® (Esketamine) Nasal Spray, TMS, ECT
Conditions TreatedTreatment-Resistant Depression, MDD with Suicidal Ideation, PTSD, Anxiety, Bipolar Depression
CostContact for pricing – Hospital-based program
InsuranceMedicare, Medicaid, and most commercial insurance accepted for Spravato® and ketamine
KAP AvailableClinical ketamine protocol – Psychiatric oversight during sessions
Clinical LeadYale Department of Psychiatry – Dr. John Krystal, Department Chair

HealingMaps Take: If there’s one ketamine program with unmatched research credentials, it’s Yale’s. The Interventional Psychiatric Program at Yale New Haven is where ketamine’s antidepressant properties were first clinically demonstrated, and the program continues to operate at the forefront of the field. This is a hospital-based setting, so expect a more clinical atmosphere than a private boutique clinic — but the tradeoff is access to a full psychiatric team, insurance coverage (including Medicare and Medicaid), and the reassurance of being treated by the institution that literally pioneered this therapy. An excellent choice for patients who prioritize evidence-based care and insurance accessibility.

Market Position: Yale New Haven Psychiatric Hospital is a Spravato-certified clinic in the Haven metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.

Is Yale New Haven Psychiatric Hospital Right for You?

✓ Choose Yale New Haven Psychiatric Hospital if:

  • You have commercial insurance and a documented treatment-resistant depression diagnosis (Spravato pathway)
  • You want supervised IV ketamine with real-time medical monitoring
  • You want academic-medical-center protocols and clinical-trial-grade oversight
  • You’re treating co-occurring depression and PTSD

✗ Look elsewhere if:

  • You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy
  • You need same-week appointments — Spravato prior authorization typically takes 1–3 weeks
  • You’re seeking ketamine for chronic pain (this clinic focuses on mental health)

Yale New Haven Psychiatric Hospital Ketamine Cost Calculator

How Much Will Ketamine Therapy Cost?

Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$525–$900
Range: $450–$1,500/session
Estimated total program
$3,150–$5,400
Range: $2,700–$9,000/6-session series
Your estimate vs. national patient-reported median Based on national tracking, adjusted for Manhattan, NY market
Select a treatment type to see pricing context.

Ketamine Protocols Compared — What’s Offered at Yale New Haven Psychiatric Hospital

Industry pricing reference. Yale New Haven Psychiatric Hospital has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

ProtocolTypical Industry CostOffered Here
IV Ketamine$350–$650/session✓ Yes
Spravato (esketamine)$0–$250 copay (insured)✓ Yes
IM Ketamine$250–$400/injection
KAP (with therapist)$400–$1,200/session
At-home troches$150–$300/month

What to Expect at Your First Yale New Haven Psychiatric Hospital Appointment

  1. Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Call (203) 688-9704 to schedule.
  2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Yale New Haven Psychiatric Hospital clinical team.
  3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 184 Liberty Street, New Haven, CT 06519. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
  4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your Yale New Haven Psychiatric Hospital Consult Call

  • How long has the Yale New Haven Psychiatric Hospital clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
  • Walk me through Yale New Haven Psychiatric Hospital’s Spravato prior authorization process versus your IV ketamine cash-pay or superbill workflow — which is the better fit for my insurance situation?
  • Have you handled Anthem BCBS Connecticut, Cigna, or Aetna Spravato authorizations — and what’s the typical PA timeline?
  • Does Yale New Haven Psychiatric Hospital require a referral from a current treating psychiatrist, and how do you handle outside-prescriber medication-management coordination?
  • What does Yale New Haven Psychiatric Hospital recommend for patients who don’t respond to the standard 6-session acute series?

Haven Ketamine Market Snapshot

Sources: CDC PLACES 2023 (Connecticut, state-level prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.

  • Adult depression in Connecticut: N/A
  • Frequent mental distress (14+ days per month): N/A
  • Adults lacking health insurance: N/A
  • Recent Haven-area inquiries to HealingMaps: A growing stream of Connecticut residents have recently contacted us seeking ketamine care

Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.

From the 2026 Ketamine Industry Report

For patients whose HSA or FSA funds are insufficient, third-party medical financing programs like CareCredit are accepted at a growing share of ketamine clinics — typically offering 6 to 24-month deferred-interest plans on the full acute-series cost of $2,100–$3,000. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.

Patient Questions about Yale New Haven Psychiatric Hospital

This 5-question summary is matched to the protocols and conditions Yale New Haven Psychiatric Hospital treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

What ketamine protocols does Yale New Haven Psychiatric Hospital offer?

Yale New Haven Psychiatric Hospital offers Spravato and IV ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.

Does Yale New Haven Psychiatric Hospital offer Spravato (esketamine)?

Yes — Yale New Haven Psychiatric Hospital offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.

Is Yale New Haven Psychiatric Hospital suited for treatment-resistant depression?

Yale New Haven Psychiatric Hospital treats depression via Spravato (FDA-approved for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Yale New Haven Psychiatric Hospital treat PTSD?

Yes — Yale New Haven Psychiatric Hospital treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Yale New Haven Psychiatric Hospital help with anxiety disorders?

Yes — Yale New Haven Psychiatric Hospital treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

This clinic offers TMS therapy as a third FDA-cleared treatment option (alongside ketamine and Spravato) for patients with treatment-resistant depression. Patients drive themselves to and from sessions, return to work the same day, and need no chaperone or recovery period. Read our complete guide to TMS therapy for FDA-cleared conditions, device differences, insurance coverage by carrier, and what to expect at your first appointment. Browse verified TMS clinics in our directory.

View all REMS-certified Spravato clinics in Connecticut and across the United States.

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Healing Maps Editorial Staff

Healing Maps Editorial Staff

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The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

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