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✓ Last verified: March 23, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Edwardsville IL (St. Louis Metro East) IV ketamine clinic serving the Greater St. Louis metro from the Illinois side of the Mississippi River. Specialized protocols for mood disorders, chronic pain, CRPS, and OCD. Madison County location accessible from downtown St. Louis (~20 min east via I-55/I-70).
| Location | Edwardsville, Illinois |
| Address | 441 South State Route 157, Suite 102, Edwardsville, IL 62025 |
| Phone | (618) 486-1914 |
| Website | 360-infusions.com |
| Treatments | IV Ketamine Infusion Therapy |
| Conditions | Depression, anxiety, PTSD, OCD, chronic pain, CRPS, neuropathic pain, suicidal ideation |
| Cost | N/A (contact for pricing) |
| Insurance | IV ketamine is self-pay; FSA/HSA typically eligible with letter of medical necessity |
| KAP Available | No |
| Clinical Lead | 360 Infusions clinical team |
HealingMaps Take: 360 Infusions occupies the St. Louis Metro East IV ketamine slot — anchored in Edwardsville, IL (Madison County), serving Greater St. Louis patients from the Illinois side of the Mississippi without requiring drive into downtown STL or to the Missouri suburbs. The clinic’s range of indications (mood + chronic pain + CRPS + OCD + suicidal ideation + neuropathic pain) is broader than most St. Louis-area ketamine practices, which typically focus on mood-only. Particularly useful for Metro East residents (Edwardsville, Collinsville, Belleville, Glen Carbon, Highland) and Madison/St. Clair County patients.
Market Position: 360 Infusions occupies the Metro East / Madison County IV ketamine slot in Greater St. Louis — distinct from the Missouri-side clinics (Midwest Institute, InVita, Clayton Behavioral, Alive Health) and offering broader pain + neuropathic indications than most regional options.
Is 360 Infusions Right for You?
✓ Choose 360 Infusions if:
- You’re located in Edwardsville, Collinsville, Belleville, Glen Carbon, Highland, or the Illinois Metro East corridor
- Your indication includes chronic pain, CRPS, or neuropathic pain alongside or instead of mood disorders
- You want a dedicated IV ketamine practice (not embedded within psychiatric medication management)
- You’re a St. Louis MO resident willing to cross into Metro East IL for treatment access (~20 min from downtown STL via I-55/I-70)
✗ Look elsewhere if:
- You want Spravato — 360 Infusions offers IV ketamine only
- You’re seeking explicit ketamine-assisted psychotherapy (KAP) with integration
- You need a Missouri-side / Clayton / West County / South County location
360 Infusions Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$416–$714
Range: $357–$1,190/session
Estimated total program
$2,499–$4,283
Range: $2,142–$7,139/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at 360 Infusions
Industry pricing reference. 360 Infusions has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First 360 Infusions Appointment
- Initial intake call — Insurance verification, Spravato prior authorization workflow if applicable, and clinical eligibility check. Call (618) 486-1914 to schedule.
- Medical evaluation — psychiatric assessment, vitals check, and review of current medications and prior treatment history with the 360 Infusions clinical team.
- First treatment session — supervised ketamine session in a monitored treatment room at 441 South State Route 157, Suite 102, Edwardsville, IL 62025.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session.
What to Ask on Your 360 Infusions Consult Call
- How long has the 360 Infusions clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- Walk me through your Spravato prior authorization process vs. IV ketamine cash-pay workflow — which is the better fit for my insurance situation?
- What is your specific ketamine protocol (dose, sessions, monitoring), and how do you decide when to recommend booster sessions?
- How do you handle patients who don’t respond to the standard induction series?
Edwardsville Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Madison County (St. Louis Metro East / Greater St. Louis), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Madison County (St. Louis Metro East / Greater St. Louis): 16.7%
- Frequent mental distress (14+ days per month): 13.4%
- Adults lacking health insurance: 8.7%
- Madison County (St. Louis Metro East / Greater St. Louis) population: 2,820,253 · median household income $71,571
- Recent Edwardsville-area inquiries to HealingMaps: A growing stream of Edwardsville-area residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,800 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“360 Infusions in Edwardsville was a 20-minute drive from my house in south St. Louis — way better than the cross-town schlep to West County. Their pain-medicine framing mattered for my CRPS-plus-depression combo; they understood both indications and dosed accordingly.”
About 360 Infusions
360 Infusions operates from 441 South State Route 157, Suite 102 in Edwardsville, Illinois (62025) — a Madison County / St. Louis Metro East location accessible from downtown St. Louis (~20 min east via I-55/I-70) and serving the Illinois Metro East communities (Edwardsville, Collinsville, Belleville, Glen Carbon, Highland) plus eastern Missouri suburbs.
The clinic’s distinguishing feature is the breadth of indications treated: mood disorders (depression, anxiety, PTSD, OCD), chronic pain conditions (CRPS / complex regional pain syndrome, neuropathic pain, general chronic pain), substance abuse, and suicidal ideation. Most St. Louis-area ketamine clinics focus on mood-only; 360 Infusions’s pain-medicine framing alongside psychiatric indications gives it a broader clinical scope.
Standard IV ketamine induction protocols follow the published evidence base for mood (typically six infusions over two to three weeks for treatment-resistant depression) and longer-duration / different dose ranges for pain protocols. CRPS in particular has an established off-label IV ketamine evidence base.
IV ketamine is cash-pay (FSA/HSA typically eligible with letter of medical necessity); insurance does not typically cover IV ketamine for mental health or pain indications. To schedule, call (618) 486-1914 or visit 360-infusions.com.
Patient Questions about 360 Infusions
This 5-question summary is matched to the protocols and conditions 360 Infusions treats. Editorial responses are HealingMaps-authored.
What ketamine protocols does 360 Infusions offer?
360 Infusions offers IV Ketamine Infusion Therapy. Confirm specific dosing schedules during your consult.
Does 360 Infusions offer Spravato (esketamine)?
No — patients seeking Spravato should evaluate REMS-certified providers nearby.
Does 360 Infusions offer ketamine-assisted psychotherapy (KAP)?
360 Infusions operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
Is 360 Infusions suited for treatment-resistant depression?
360 Infusions treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Can 360 Infusions help with anxiety disorders?
Yes — 360 Infusions treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in Illinois and across the United States.
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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