✓ Last verified: February 7, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Advanced Ketamine Services in Edmond provides IV ketamine infusion therapy within the Signature Skincare medical practice. Located in north OKC’s affluent Edmond suburb, the clinic offers ketamine treatments for depression, anxiety, PTSD, and chronic pain alongside their broader medical aesthetics services.
| Google Reviews | ⭐ Edmond suburb clinic |
| Location | Edmond, Oklahoma |
| Address | 1025 N Bryant Ave, Edmond, OK 73034 |
| Phone | (405) 285-5522 |
| Website | signatureskincare.com |
| Treatments | IV Ketamine Infusions |
| Conditions Treated | Depression, Anxiety, PTSD, Chronic Pain |
| Cost | Contact clinic for pricing |
| Insurance | Contact clinic for details |
| KAP Available | Not specified |
| Clinical Lead | Contact clinic |
HealingMaps Take: Advanced Ketamine Services provides ketamine therapy in Edmond’s comfortable medical setting. Their integration within a broader medical practice means clinical infrastructure and support staff are already in place. A convenient option for north OKC metro residents.
Market Position: Advanced Ketamine Services is an IV-ketamine-focused clinic in the Edmond metro — the most common cash-pay protocol in the HealingMaps verified directory.
Industry pricing reference. Advanced Ketamine Services has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
Sources: CDC PLACES 2023 (Oklahoma County, OK, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
For patients whose HSA or FSA funds are insufficient, third-party medical financing programs like CareCredit are accepted at a growing share of ketamine clinics — typically offering 6 to 24-month deferred-interest plans on the full acute-series cost of $2,100–$3,000. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
This 4-question summary is matched to the protocols and conditions Advanced Ketamine Services treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Advanced Ketamine Services treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Advanced Ketamine Services treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — Advanced Ketamine Services treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Yes — Advanced Ketamine Services treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
View all REMS-certified Spravato clinics in Oklahoma and across the United States.
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