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✓ Last verified: March 31, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Amanda Itzkoff MD Manhattan in Manhattan, New York logo

Known For: Midtown Manhattan office of Dr. Amanda Itzkoff offering Spravato (esketamine) and ketamine-assisted psychotherapy with concierge-level psychiatric care on Madison Avenue.

Google Reviews4.9 ⭐ (50+ reviews)
LocationMidtown East, Manhattan
Address515 Madison Ave, 21st Floor, New York, NY 10022
Phone(917) 982-2184
Websitepsychiatristsnyc.com
TreatmentsSpravato (esketamine), ketamine-assisted psychotherapy, psychiatric medication management
ConditionsTreatment-resistant depression, anxiety, PTSD, OCD, bipolar disorder
CostContact for pricing; Spravato may be covered by insurance
InsuranceAccepts select insurance for Spravato; other services may be out-of-network
KAP AvailableYes – ketamine-assisted psychotherapy offered
Clinical LeadDr. Amanda Itzkoff, MD – Board-Certified Psychiatrist

HealingMaps Take: This Midtown East location provides the same high-quality psychiatrist-led ketamine care as Dr. Itzkoff’s other offices. The Madison Avenue address is convenient for Midtown professionals, and the practice’s Spravato certification means insurance coverage may be available for qualifying patients. A strong option for those seeking integrated psychiatric and ketamine treatment.

Market Position: Amanda Itzkoff MD is a Spravato-certified clinic in the Manhattan metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.

Is Amanda Itzkoff MD Right for You?

✓ Choose Amanda Itzkoff MD if:

  • You have commercial insurance and a documented treatment-resistant depression diagnosis (Spravato pathway)
  • You’re seeking ketamine-assisted psychotherapy (KAP) with a licensed therapist alongside dosing
  • You’re treating co-occurring depression and PTSD

✗ Look elsewhere if:

  • You’re seeking cash-pay IV ketamine instead of insurance-billed Spravato
  • You need same-week appointments — Spravato prior authorization typically takes 1–3 weeks
  • You’re seeking ketamine for chronic pain (this clinic focuses on mental health)

Amanda Itzkoff MD Ketamine Cost Calculator

How Much Will Ketamine Therapy Cost?

Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$525–$900
Range: $450–$1,500/session
Estimated total program
$3,150–$5,400
Range: $2,700–$9,000/6-session series
Your estimate vs. national patient-reported median Based on national tracking, adjusted for Manhattan, NY market
Select a treatment type to see pricing context.

Ketamine Protocols Compared — What’s Offered at Amanda Itzkoff MD

Industry pricing reference. Amanda Itzkoff MD has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

ProtocolTypical Industry CostOffered Here
IV Ketamine$350–$650/session
Spravato (esketamine)$0–$250 copay (insured)✓ Yes
IM Ketamine$250–$400/injection
KAP (with therapist)$400–$1,200/session✓ Yes
At-home troches$150–$300/month

What to Expect at Your First Amanda Itzkoff MD Appointment

  1. Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Call (917) 982-2184 or visit psychiatristsnyc.com to schedule.
  2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Amanda Itzkoff MD clinical team.
  3. First treatment session — supervised Spravato (intranasal esketamine) in a private treatment room, lasting approximately 90 minutes (40-minute session + 60 minutes monitoring). Sessions are held at 515 Madison Ave, 21st Floor, New York, NY 10022. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
  4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your Spravato session.

What to Ask on Your Amanda Itzkoff MD Consult Call

  • How long has the Amanda Itzkoff MD clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
  • How long does Amanda Itzkoff MD’s Spravato prior authorization typically take with my specific insurance plan, and what happens if it’s denied?
  • Which New York commercial insurers (Aetna, UnitedHealthcare, Empire BCBS, Oxford, Healthfirst) have you successfully obtained Spravato prior authorization through?
  • Is the therapist who guides KAP sessions independently licensed, and how long are integration sessions after the dosing portion?
  • What does Amanda Itzkoff MD recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about Amanda Itzkoff MD

This 5-question summary is matched to the protocols and conditions Amanda Itzkoff MD treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

What ketamine protocols does Amanda Itzkoff MD offer?

Amanda Itzkoff MD offers Spravato and KAP — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.

Does Amanda Itzkoff MD offer Spravato (esketamine)?

Yes — Amanda Itzkoff MD offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.

Does Amanda Itzkoff MD offer ketamine-assisted psychotherapy (KAP)?

Yes — Amanda Itzkoff MD offers KAP, which combines ketamine dosing with structured psychotherapy during the dissociative window. KAP sessions are longer than standalone infusions and priced accordingly. A reasonable consult question: whether KAP is delivered by a single integrated provider, or by a separate therapist working with the prescribing clinician.

Is Amanda Itzkoff MD suited for treatment-resistant depression?

Amanda Itzkoff MD treats depression via Spravato (FDA-approved for TRD), and KAP for trauma-anchored depression. The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Can Amanda Itzkoff MD help with anxiety disorders?

Yes — Amanda Itzkoff MD treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

View all REMS-certified Spravato clinics in New York and across the United States.

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Healing Maps Editorial Staff

Healing Maps Editorial Staff

View all posts by Healing Maps Editorial Staff

The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

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