✓ Last verified: March 31, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Midtown Manhattan office of Dr. Amanda Itzkoff offering Spravato (esketamine) and ketamine-assisted psychotherapy with concierge-level psychiatric care on Madison Avenue.
| Google Reviews | 4.9 ⭐ (50+ reviews) |
| Location | Midtown East, Manhattan |
| Address | 515 Madison Ave, 21st Floor, New York, NY 10022 |
| Phone | (917) 982-2184 |
| Website | psychiatristsnyc.com |
| Treatments | Spravato (esketamine), ketamine-assisted psychotherapy, psychiatric medication management |
| Conditions | Treatment-resistant depression, anxiety, PTSD, OCD, bipolar disorder |
| Cost | Contact for pricing; Spravato may be covered by insurance |
| Insurance | Accepts select insurance for Spravato; other services may be out-of-network |
| KAP Available | Yes – ketamine-assisted psychotherapy offered |
| Clinical Lead | Dr. Amanda Itzkoff, MD – Board-Certified Psychiatrist |
HealingMaps Take: This Midtown East location provides the same high-quality psychiatrist-led ketamine care as Dr. Itzkoff’s other offices. The Madison Avenue address is convenient for Midtown professionals, and the practice’s Spravato certification means insurance coverage may be available for qualifying patients. A strong option for those seeking integrated psychiatric and ketamine treatment.
Market Position: Amanda Itzkoff MD is a Spravato-certified clinic in the Manhattan metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.
Industry pricing reference. Amanda Itzkoff MD has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | — |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | ✓ Yes |
| At-home troches | $150–$300/month | — |
This 5-question summary is matched to the protocols and conditions Amanda Itzkoff MD treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Amanda Itzkoff MD offers Spravato and KAP — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.
Yes — Amanda Itzkoff MD offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.
Yes — Amanda Itzkoff MD offers KAP, which combines ketamine dosing with structured psychotherapy during the dissociative window. KAP sessions are longer than standalone infusions and priced accordingly. A reasonable consult question: whether KAP is delivered by a single integrated provider, or by a separate therapist working with the prescribing clinician.
Amanda Itzkoff MD treats depression via Spravato (FDA-approved for TRD), and KAP for trauma-anchored depression. The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Amanda Itzkoff MD treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
View all REMS-certified Spravato clinics in New York and across the United States.
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