✓ Last verified: February 14, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: CNS Center of Arizona is a psychiatry practice in Scottsdale led by Dr. Ramiro Guillen and Dr. Marilyn Pupo-Guillen, both specialists in adult and pediatric psychiatry. In practice since 2004, the clinic offers ketamine infusion therapy alongside comprehensive psychiatric care. Their protocol includes a thorough assessment before recommending ketamine, with a typical course of six infusions over one to three weeks.
| Google Reviews | ⭐ 4.0 out of 5 (Dr. Guillen — 22 ratings on WebMD) |
| Location | Scottsdale, Arizona |
| Address | 11333 North Scottsdale Road, Suite 260, Scottsdale, AZ 85254 |
| Phone | (480) 367-1500 |
| Website | cnscenteraz.com |
| Treatments | Ketamine Infusions, Psychiatric Evaluations, Medication Management, Child & Adolescent Psychiatry |
| Conditions Treated | Treatment-Resistant Depression, Anxiety, PTSD, Bipolar Disorder, OCD, ADHD |
| Cost | Contact for pricing |
| Insurance | Contact for details |
| KAP Available | No |
| Clinical Lead | Dr. Ramiro Guillen, MD — Dr. Marilyn Pupo-Guillen, MD |
HealingMaps Take: CNS Center of Arizona brings a psychiatry-first approach to ketamine therapy, which is a meaningful advantage for patients with complex mental health conditions. Having board-certified psychiatrists administer ketamine means the treatment is integrated into a broader psychiatric care plan rather than offered in isolation. Their structured protocol of six infusions with follow-up evaluations demonstrates a thoughtful, evidence-based approach. The clinic has been operating in Scottsdale since 2004, offering long-standing stability in the community.
Market Position: CNS Center of Arizona treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.
Industry pricing reference. CNS Center of Arizona has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine Infusion | $350–$650/session | ✓ |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with integrated talk therapy) | $400–$1,200/session | — |
| At-home oral troches | $150–$300/month | — |
Sources: CDC PLACES 2023 (Maricopa County, AZ, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
58.1% of patients say telehealth increases access to ketamine therapy — even among those skeptical of at-home protocols, virtual consultation consistently ranks as a net positive. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
This question is matched to the conditions CNS Center of Arizona treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Yes — CNS Center of Arizona treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
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