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✓ Last verified: March 23, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Established 2018, Evolve Health is a Portland-area interventional psychiatry practice offering all three FDA-approved or evidence-supported depression treatments — Spravato (esketamine), TMS, and IV ketamine — across Portland (SE Lake Rd) and Beaverton (Cornell Rd) locations.
| Location | Portland, Oregon |
| Address | 6400 SE Lake Rd, Suite 155, Portland, OR 97222 |
| Phone | (503) 447-3285 |
| Website | evolvehealthcares.com |
| Treatments | Spravato (Esketamine) + IV Ketamine + TMS (Transcranial Magnetic Stimulation) |
| Conditions | Treatment-resistant depression, major depression with suicidal ideation, anxiety, PTSD |
| Cost | N/A (contact for pricing) |
| Insurance | Spravato typically insurance-billed; IV ketamine self-pay (FSA/HSA eligible) |
| KAP Available | No |
| Clinical Lead | Evolve Health interventional psychiatry team |
HealingMaps Take: Evolve Health is one of the few Portland-area clinics with Spravato, TMS, AND IV ketamine integrated within a single interventional psychiatry practice — meaningful for patients whose treatment plan may involve more than one modality. The SE Lake Road location anchors southeast Portland / Milwaukie / Clackamas County; the Beaverton sister location extends westside coverage. Spravato is the FDA-approved insurance-covered esketamine pathway; IV ketamine is cash-pay off-label.
Market Position: Evolve Health occupies the integrated-interventional-psychiatry slot in the Portland market (Spravato + TMS + IV ketamine in one practice) — distinct from the standalone IV ketamine clinics (Portland Ketamine Clinic, NW Ketamine Infusion) and the KAP-oriented Áureo and Synaptic Institute.
Is Evolve Health Right for You?
✓ Choose Evolve Health if:
- You want Spravato, TMS, AND IV ketamine integrated within a single clinical team rather than coordinating across separate practices
- You’re located in southeast Portland, Milwaukie, Oak Grove, Clackamas County, or Beaverton (sister location)
- You have commercial insurance and a treatment-resistant depression diagnosis (Spravato + TMS pathways)
- You value a practice with insurance-billing infrastructure for both Spravato and TMS
✗ Look elsewhere if:
- You’re seeking ketamine-assisted psychotherapy (KAP) with structured integration — Evolve runs a medical-model program
- You need a downtown Portland, Northwest Portland, or Pearl District location
Evolve Health Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$416–$714
Range: $357–$1,190/session
Estimated total program
$2,499–$4,283
Range: $2,142–$7,139/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at Evolve Health
Industry pricing reference. Evolve Health has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First Evolve Health Appointment
- Initial intake call — Insurance verification, Spravato prior authorization workflow if applicable, and clinical eligibility check. Call (503) 447-3285 to schedule.
- Medical evaluation — psychiatric assessment, vitals check, and review of current medications and prior treatment history with the Evolve Health clinical team.
- First treatment session — supervised ketamine session in a monitored treatment room at 6400 SE Lake Rd, Suite 155, Portland, OR 97222.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session.
What to Ask on Your Evolve Health Consult Call
- How long has the Evolve Health clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- Walk me through your Spravato prior authorization process vs. IV ketamine cash-pay workflow — which is the better fit for my insurance situation?
- What is your specific ketamine protocol (dose, sessions, monitoring), and how do you decide when to recommend booster sessions?
- How do you handle patients who don’t respond to the standard induction series?
Portland Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Clackamas County / Multnomah County (Portland metro), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Clackamas County / Multnomah County (Portland metro): 16.7%
- Frequent mental distress (14+ days per month): 13.4%
- Adults lacking health insurance: 8.7%
- Clackamas County / Multnomah County (Portland metro) population: 2,512,859 · median household income $94,005
- Recent Portland-area inquiries to HealingMaps: A growing stream of Portland-area residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,800 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“Evolve was the only Portland clinic where I could do Spravato AND TMS at the same office without juggling two practices. The SE Lake Road location was easier for me than going downtown, and they handled my insurance prior auth in about three weeks.”
About Evolve Health
Evolve Health operates from 6400 SE Lake Road, Suite 155 in Portland, Oregon (97222), with a sister location at 16100 NW Cornell Road in Beaverton serving the westside. The Portland location anchors southeast Portland, Milwaukie, Oak Grove, and the Clackamas County corridor. The practice was established in 2018.
Evolve Health is one of the few Portland-area clinics offering Spravato (esketamine), TMS (transcranial magnetic stimulation), AND IV ketamine within a single interventional psychiatry practice — meaningful for patients whose treatment plan may benefit from sequential or combined protocols. Both Spravato and TMS are FDA-approved for treatment-resistant depression and typically covered by commercial insurance plans.
The clinic is REMS-certified for Spravato, meeting the FDA-required two-hour in-office observation window after each esketamine dose. IV ketamine is offered as a cash-pay off-label option for patients who don’t qualify for Spravato or who want the IV protocol’s faster onset. Conditions treated include treatment-resistant depression, major depression with suicidal ideation, anxiety, and PTSD.
Office hours are Monday through Friday, 9:00 am to 5:00 pm. To schedule, call (503) 447-3285 — for insurance verification call (971) 358-9292 — or visit evolvehealthcares.com.
Patient Questions about Evolve Health
This 5-question summary is matched to the protocols and conditions Evolve Health treats. Editorial responses are HealingMaps-authored.
What ketamine protocols does Evolve Health offer?
Evolve Health offers Spravato (Esketamine) + IV Ketamine + TMS (Transcranial Magnetic Stimulation). Confirm specific dosing schedules during your consult.
Does Evolve Health offer Spravato (esketamine)?
Yes — Evolve Health offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose.
Does Evolve Health offer ketamine-assisted psychotherapy (KAP)?
Evolve Health operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
Is Evolve Health suited for treatment-resistant depression?
Evolve Health treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Can Evolve Health help with anxiety disorders?
Yes — Evolve Health treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in Oregon and across the United States.
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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