✓ Last verified: April 6, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Pain management specialist Dr. Shonith Manohar offering ketamine infusions for chronic pain alongside mood disorder treatment — the strongest pain-focused ketamine option in Jacksonville. Review Scores: Established pain management practice Location: Jacksonville, FL Address: 8259 Bayberry Rd., Suite 1, Jacksonville, FL 32256 Phone: (904) 737-7246 Website: floridaregionalpain.com Treatments: IV Ketamine Infusions Conditions Treated: Chronic Pain, Anxiety, Depression Cost: Contact for pricing Insurance: Contact for details KAP Available?: No Clinical Lead: Dr. Shonith Manohar, MD — Pain Management Specialist HealingMaps Take: For patients whose depression or anxiety is intertwined with chronic pain, Dr. Manohar’s pain management expertise makes Florida Regional Pain Management a uniquely qualified option. Lower-dose IV ketamine targets both pain and mood simultaneously. For more options, see our guide to finding the best ketamine therapy clinics.Learn more about this treatment:
Market Position: Florida Regional Pain Management is a Spravato-certified clinic in the Jacksonville metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.
This 4-question summary covers the most common patient questions for ketamine clinics in Jacksonville, Florida. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Florida Regional Pain Management offers verified ketamine therapy services in Jacksonville. Specific protocols can include IV ketamine infusion, IM ketamine injection, oral troches, ketamine-assisted psychotherapy (KAP), or Spravato (FDA-approved esketamine) — verify the specific protocol mix with the clinic during your consult call. Multi-protocol practices typically offer more flexibility for matching the modality to your diagnosis and insurance coverage.
Treatment-resistant depression (TRD) — typically defined as failure on two or more antidepressant trials — is the most common qualifier for ketamine therapy and the FDA-approved indication for Spravato. Patients meeting that bar are typical candidates at ketamine clinics like Florida Regional Pain Management. If insurance coverage matters, ask whether they offer Spravato (insurance-covered for TRD) versus IV ketamine (typically self-pay).
Most ketamine clinics treat PTSD and anxiety alongside depression — these three conditions account for ~46% of HealingMaps patient inquiries. Some clinics also treat chronic pain (CRPS, fibromyalgia, neuropathic pain), though pain protocols differ from mental-health protocols (longer infusion times, higher doses). Ask Florida Regional Pain Management which specific conditions they treat most often and how their protocols differ by indication.
Compare ketamine clinics in Jacksonville, Florida on three axes: (1) protocol mix — multi-protocol clinics offer flexibility; (2) clinical lead — psychiatrist-led clinics typically include KAP integration, anesthesiologist-led clinics typically focus on infusion; (3) insurance posture — Spravato-certified providers can run insurance coverage; cash-only IV clinics cannot. Florida Regional Pain Management’s positioning on these axes determines whether it’s the right fit for your specific diagnosis and budget.
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