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✓ Last verified: February 22, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Indianapolis’s dedicated ketamine practice — customized infusions for depression, anxiety, PTSD, and OCD. Hundreds of patients helped since founding in December 2021.

Review Scores: Yelp rated (Dec 2025) · Consistently positive patient feedback

Location: Indianapolis, IN (Castleton area)

Address: 6801 Lake Plaza Dr, Suite B-209, Indianapolis, IN 46220

Phone: (463) 466-7437

Website: hoosierketamine.com

Treatments: IV Ketamine Infusions, Vitamin Infusions

Conditions Treated: Depression, Anxiety, PTSD, OCD, Suicidal Ideation

Cost: Contact for pricing

Insurance: Contact for details

KAP Available?: No

Clinical Lead: Experienced ketamine therapy team

HealingMaps Take: Hoosier Ketamine & Wellness has helped hundreds of patients since launching in December 2021. Their Castleton-area location is centrally positioned in Indianapolis, and their team customizes each infusion to the patient’s specific needs. Patients consistently praise the compassionate care and knowledgeable staff. For more options, see our guide to finding the best ketamine therapy clinics.

Market Position: Hoosier Ketamine & Wellness is an IV-ketamine-focused clinic in the Indianapolis metro — the most common cash-pay protocol in the HealingMaps verified directory.

Is Hoosier Ketamine & Wellness Right for You?

✓ Choose Hoosier Ketamine & Wellness if:

  • You want supervised IV ketamine with real-time medical monitoring
  • You’re treating co-occurring depression and PTSD

✗ Look elsewhere if:

  • You need Spravato (FDA-approved esketamine) covered by your insurance
  • You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy
  • You’re seeking ketamine for chronic pain (this clinic focuses on mental health)

Hoosier Ketamine & Wellness Ketamine Cost Calculator

How Much Will Ketamine Therapy Cost?

Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$525–$900
Range: $450–$1,500/session
Estimated total program
$3,150–$5,400
Range: $2,700–$9,000/6-session series
Your estimate vs. national patient-reported median Based on national tracking, adjusted for Manhattan, NY market
Select a treatment type to see pricing context.

Ketamine Protocols Compared — What’s Offered at Hoosier Ketamine & Wellness

Industry pricing reference. Hoosier Ketamine & Wellness has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

ProtocolTypical Industry CostOffered Here
IV Ketamine$350–$650/session✓ Yes
Spravato (esketamine)$0–$250 copay (insured)
IM Ketamine$250–$400/injection
KAP (with therapist)$400–$1,200/session
At-home troches$150–$300/month

What to Expect at Your First Hoosier Ketamine & Wellness Appointment

  1. Initial intake call — Brief medical history review, depression and anxiety screening, and medical clearance for IV ketamine. Call (463) 466-7437 to schedule.
  2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Hoosier Ketamine & Wellness clinical team.
  3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 6801 Lake Plaza Dr, Suite B-209, Indianapolis, IN 46220. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
  4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your Hoosier Ketamine & Wellness Consult Call

  • How long has the Hoosier Ketamine & Wellness clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
  • Does Hoosier Ketamine & Wellness provide a superbill for out-of-network insurance reimbursement, and what’s a typical 6-session total cost including any follow-up?
  • Have you handled Anthem BCBS Indiana, UnitedHealthcare, or Indiana University Health Plans Spravato authorizations, and how long is your typical PA timeline?
  • What does Hoosier Ketamine & Wellness recommend for patients who don’t respond to the standard 6-session acute series?

Indianapolis Ketamine Market Snapshot

Sources: CDC PLACES 2023 (Marion County, IN, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.

  • Adult depression in Marion County, IN: 25.5%
  • Frequent mental distress (14+ days per month): 17.8%
  • Adults lacking health insurance: 10.7%
  • Marion County population: 971,737 · median household income $59,504
  • Recent Indianapolis-area inquiries to HealingMaps: A growing stream of Indiana residents have recently contacted us seeking ketamine care

Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.

From the 2026 Ketamine Industry Report

Oral and sublingual ketamine maintenance typically runs $150 per month — the lowest ongoing cost of any protocol and a common long-term strategy for patients managing treatment-resistant depression. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.

Patient Questions about Hoosier Ketamine & Wellness

This 3-question summary is matched to the protocols and conditions Hoosier Ketamine & Wellness treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Is Hoosier Ketamine & Wellness suited for treatment-resistant depression?

Hoosier Ketamine & Wellness treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Hoosier Ketamine & Wellness treat PTSD?

Yes — Hoosier Ketamine & Wellness treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Hoosier Ketamine & Wellness help with anxiety disorders?

Yes — Hoosier Ketamine & Wellness treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

Learn more about this treatment:

See also: — our ketamine therapy resources.

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Healing Maps Editorial Staff

Healing Maps Editorial Staff

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The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

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