Landmark Health Systems – Buffalo, New York Ketamine Clinics

✓ Last verified: February 24, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: The Buffalo psychiatrist who delivered Western New York’s first Spravato treatment — Dr. Jarod Masci’s Landmark Health Systems is a SPRAVATO REMS-certified center offering esketamine and TMS within a full outpatient psychiatric practice in Buffalo’s historic Allentown District.

💡 No clinic-specific pricing posted? See our ketamine therapy cost guide for typical pricing ranges by treatment type and insurance pathways.

HealingMaps Take: Landmark Health Systems holds a specific historical distinction in the Western New York psychiatric market: Dr. Jarod Masci administered the first Spravato treatment to a WNY patient, marking the region’s entry into FDA-approved esketamine therapy. That early-adopter status translates into nearly a decade of refined clinical protocols, insurance navigation expertise, and REMS compliance experience that newer Spravato providers cannot match. The 387 Franklin Street location in Buffalo’s historic Allentown District is walkable from downtown Buffalo and serves patients across the greater Buffalo metro including Amherst, Williamsville, Orchard Park, and West Seneca. Offering both Spravato AND Transcranial Magnetic Stimulation (TMS) provides modality flexibility — patients who don’t respond to one treatment can pivot to the other without switching clinics. The broader practice suite (psychiatry, medication management, counseling) means Spravato is delivered within a full mental health medical home rather than as a standalone service, which matters clinically because esketamine works best when combined with ongoing psychiatric care. Extended hours including Saturdays 9-3 accommodate working patients who can’t take time off during the week for twice-weekly induction sessions. For Buffalo patients with treatment-resistant depression who want the most experienced Spravato provider in Western New York, Landmark Health Systems is the clear clinical anchor.

Market Position: Landmark Health Systems is a Spravato-certified clinic in the Buffalo metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.

Landmark Health Systems Ketamine Cost Calculator

Ketamine Protocols Compared — What’s Offered at Landmark Health Systems

Industry pricing reference. Landmark Health Systems has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

What to Expect at Your First Landmark Health Systems Appointment

1. Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Call (716) 462-0284 to schedule.
2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Landmark Health Systems clinical team.
3. First treatment session — supervised Spravato (intranasal esketamine) in a private treatment room, lasting approximately 90 minutes (40-minute session + 60 minutes monitoring). Sessions are held at 387 Franklin Street, Buffalo, NY 14202. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your Spravato session.

What to Ask on Your Landmark Health Systems Consult Call

• How long has the Landmark Health Systems clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
• How long does Landmark Health Systems’s Spravato prior authorization typically take with my specific insurance plan, and what happens if it’s denied?
• Which New York commercial insurers (Aetna, UnitedHealthcare, Empire BCBS, Oxford, Healthfirst) have you successfully obtained Spravato prior authorization through?
• How is the two-hour REMS monitoring period structured — quiet recovery room, group setting, or staff observation?
• What does Landmark Health Systems recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about Landmark Health Systems

This 2-question summary is matched to the protocols and conditions Landmark Health Systems treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Does Landmark Health Systems offer Spravato (esketamine)?

Yes — Landmark Health Systems offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.

Is Landmark Health Systems suited for treatment-resistant depression?

Landmark Health Systems treats depression via Spravato (FDA-approved for TRD). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

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