✓ Last verified: March 27, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Multi-specialty medical center offering both IV and intranasal ketamine for mood disorders and chronic pain in the South Loop
| Google Reviews | 35 reviews on Yelp |
| Location | South Loop, Chicago, Illinois |
| Address | 1921 S Michigan Ave, Chicago, IL 60616 |
| Phone | (312) 414-1088 |
| Website | loopmedicalcenter.com |
| Treatments | IV Ketamine Infusion, Intranasal Ketamine, Pain Management, Regenerative Medicine |
| Conditions | Depression, Bipolar Disorder, Anxiety, PTSD, OCD, Fibromyalgia, Addiction, Chronic Pain |
| Cost | Contact clinic for pricing |
| Insurance | Contact clinic |
| KAP Available | Contact clinic |
| Clinical Lead | Contact clinic |
HealingMaps Take: Loop Medical Center offers a broad approach to ketamine therapy with both IV and intranasal administration options, treating an extensive range of conditions from mood disorders to chronic pain and addiction. As a multi-specialty medical center, they can address ketamine therapy within the context of broader medical care. Their South Loop location on Michigan Avenue is centrally located and easily accessible. A second location in Streeterville provides additional convenience for North Side patients.
Market Position: Loop Medical Center is a Spravato-certified clinic in the Chicago metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.
Industry pricing reference. Loop Medical Center has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
This 6-question summary is matched to the protocols and conditions Loop Medical Center treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Loop Medical Center offers Spravato and IV ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.
Yes — Loop Medical Center offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.
Loop Medical Center treats depression via Spravato (FDA-approved for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Loop Medical Center treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — Loop Medical Center treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Yes — Loop Medical Center treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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