✓ Edited by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Harvard Medical School affiliate · Belmont-campus academic psychiatric hospital ketamine program housed in the ECT/TMS suite of the de Marneffe Building. One of the few Boston-area ketamine clinics with full academic medical center backing.
| Location | Belmont, Massachusetts |
| Address | 115 Mill Street, Belmont, MA 02478 |
| Phone | (617) 855-2364 |
| Website | mcleanhospital.org |
| Treatments | IV Ketamine + Spravato (Esketamine) — academic medical center program |
| Conditions | Major depressive disorder, treatment-resistant depression, bipolar depression — adults |
| Cost | N/A (contact for pricing) |
| Insurance | Spravato typically insurance-billed; IV ketamine self-pay (FSA/HSA eligible) |
| KAP Available | No |
| Clinical Lead | McLean Hospital Ketamine Service psychiatry team (Harvard Medical School affiliate) |
HealingMaps Take: McLean Hospital is one of the world’s leading psychiatric hospitals — a Harvard Medical School affiliate that pairs the ketamine service with the broader ECT/TMS interventional psychiatry stack and full inpatient psychiatric care. For Boston-area patients with severe treatment-resistant depression who want academic-medical-center clinical depth (rather than a standalone infusion clinic), McLean is the natural choice. The Belmont main campus location is accessible from Cambridge, Watertown, Waltham, and the western Boston suburbs.
Market Position: McLean Hospital Ketamine Service is the Harvard Medical School-affiliated academic-medical-center option for Boston-area ketamine — distinct from the independent infusion clinics that dominate the rest of the Boston market. Treatment fits within McLean’s broader psychiatric continuum (outpatient + inpatient + ECT + TMS).
Industry pricing reference. McLean Hospital has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
Sources: CDC PLACES 2025 release (Middlesex County (Boston metro), model-based crude prevalence among adults) · HealingMaps proprietary patient inquiry data.
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, analyzed 132 clinic websites, and collected 658 practitioner survey responses. County health figures are CDC PLACES model-based estimates, not clinic data.
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
McLean Hospital’s Ketamine Service operates from the main campus at 115 Mill Street in Belmont, Massachusetts, with the ketamine program housed in the ECT/TMS suite within the de Marneffe Building. McLean is a Harvard Medical School affiliate and one of the largest and most respected psychiatric hospitals in the United States.
The ketamine service is designed for adults with major depressive disorder, treatment-resistant depression, and bipolar depression. Treatment fits within McLean’s broader psychiatric continuum, which includes outpatient services, inpatient hospitalization, ECT (electroconvulsive therapy), and TMS (transcranial magnetic stimulation) — meaning patients can move between interventional protocols based on response and acuity.
Because of the academic medical center model, intake processes are more thorough than at standalone infusion clinics — psychiatric evaluation, treatment history review, and clinical eligibility screening are required before any ketamine dosing. For severe and complex cases this depth is the primary value; for patients seeking simpler outpatient access, the standalone Boston-area ketamine clinics in higher ranks of this list may be a better fit.
To begin intake at McLean’s Ketamine Service, call (617) 855-2364. The main hospital number is (617) 855-2000. Insurance coverage varies — confirm Spravato in-network status and IV ketamine self-pay rates during intake.
This 5-question summary is matched to the protocols and conditions McLean Hospital treats. Editorial responses are HealingMaps-authored.
McLean Hospital offers IV Ketamine + Spravato (Esketamine) — academic medical center program. Confirm specific dosing schedules during your consult.
Yes — McLean Hospital offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose.
McLean Hospital operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
McLean Hospital treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Yes — McLean Hospital treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in Massachusetts and across the United States.
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