✓ Last verified: March 23, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Harvard Medical School affiliate · Belmont-campus academic psychiatric hospital ketamine program housed in the ECT/TMS suite of the de Marneffe Building. One of the few Boston-area ketamine clinics with full academic medical center backing.
| Location | Belmont, Massachusetts |
| Address | 115 Mill Street, Belmont, MA 02478 |
| Phone | (617) 855-2364 |
| Website | mcleanhospital.org |
| Treatments | IV Ketamine + Spravato (Esketamine) — academic medical center program |
| Conditions | Major depressive disorder, treatment-resistant depression, bipolar depression — adults |
| Cost | N/A (contact for pricing) |
| Insurance | Spravato typically insurance-billed; IV ketamine self-pay (FSA/HSA eligible) |
| KAP Available | No |
| Clinical Lead | McLean Hospital Ketamine Service psychiatry team (Harvard Medical School affiliate) |
HealingMaps Take: McLean Hospital is one of the world’s leading psychiatric hospitals — a Harvard Medical School affiliate that pairs the ketamine service with the broader ECT/TMS interventional psychiatry stack and full inpatient psychiatric care. For Boston-area patients with severe treatment-resistant depression who want academic-medical-center clinical depth (rather than a standalone infusion clinic), McLean is the natural choice. The Belmont main campus location is accessible from Cambridge, Watertown, Waltham, and the western Boston suburbs.
Market Position: McLean Hospital Ketamine Service is the Harvard Medical School-affiliated academic-medical-center option for Boston-area ketamine — distinct from the independent infusion clinics that dominate the rest of the Boston market. Treatment fits within McLean’s broader psychiatric continuum (outpatient + inpatient + ECT + TMS).
Industry pricing reference. McLean Hospital has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
Sources: CDC PLACES 2023 (Middlesex County (Boston metro), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
“McLean’s name carried weight with my insurance company and with the providers I’d been working with — the academic-medical-center framing meant my psychiatrist trusted the protocol. The Belmont campus felt clinical and supervised in a way that helped, not hindered.”
McLean Hospital’s Ketamine Service operates from the main campus at 115 Mill Street in Belmont, Massachusetts, with the ketamine program housed in the ECT/TMS suite within the de Marneffe Building. McLean is a Harvard Medical School affiliate and one of the largest and most respected psychiatric hospitals in the United States.
The ketamine service is designed for adults with major depressive disorder, treatment-resistant depression, and bipolar depression. Treatment fits within McLean’s broader psychiatric continuum, which includes outpatient services, inpatient hospitalization, ECT (electroconvulsive therapy), and TMS (transcranial magnetic stimulation) — meaning patients can move between interventional protocols based on response and acuity.
Because of the academic medical center model, intake processes are more thorough than at standalone infusion clinics — psychiatric evaluation, treatment history review, and clinical eligibility screening are required before any ketamine dosing. For severe and complex cases this depth is the primary value; for patients seeking simpler outpatient access, the standalone Boston-area ketamine clinics in higher ranks of this list may be a better fit.
To begin intake at McLean’s Ketamine Service, call (617) 855-2364. The main hospital number is (617) 855-2000. Insurance coverage varies — confirm Spravato in-network status and IV ketamine self-pay rates during intake.
This 5-question summary is matched to the protocols and conditions McLean Hospital treats. Editorial responses are HealingMaps-authored.
McLean Hospital offers IV Ketamine + Spravato (Esketamine) — academic medical center program. Confirm specific dosing schedules during your consult.
Yes — McLean Hospital offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose.
McLean Hospital operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
McLean Hospital treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Yes — McLean Hospital treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in Massachusetts and across the United States.
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