Optimal Medical Group – Fresno, California Ketamine Clinics

✓ Last verified: March 23, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Physician-owned Fresno ketamine clinic led by Dr. Juan Chavez and Dr. Lucia Mireles-Chavez — bringing two MDs into every treatment decision in a Central Valley market historically starved for physician-led interventional psychiatry.

HealingMaps Take: Optimal Medical Group fills a critical gap in the Fresno market. As one of the few physician-owned ketamine clinics in the Central Valley — with TWO MDs (Dr. Juan Chavez and Dr. Lucia Mireles-Chavez) directly involved in patient care — the practice brings a level of clinical rigor that nurse-led or PA-led infusion clinics simply cannot match. Having two physicians means coverage during vacations, real peer consultation on complex cases, and the ability to handle unexpected clinical situations without transferring to emergency care. The standard six-infusion protocol over two weeks (three infusions per week) follows current ketamine evidence; 30-45 minute sessions are efficient for working patients. Treating depression, anxiety, trauma, and chronic pain within an integrative medical home means patients can access coordinated care — ketamine alongside broader wellness therapies — rather than shuttling between specialists. The Fresno Milburn Avenue location in northwest Fresno is accessible from the 99 and 41 freeways and serves patients across the Central Valley from Madera to Visalia. For Central Valley patients who want MD-grade clinical oversight for ketamine treatment without traveling to the Bay Area or Los Angeles, Optimal Medical Group is the most physician-dense option in the market.

Market Position: Optimal Medical Group is an IV-ketamine-focused clinic in the Fresno metro — the most common cash-pay protocol in the HealingMaps verified directory.

Optimal Medical Group Ketamine Cost Calculator

Ketamine Protocols Compared — What’s Offered at Optimal Medical Group

Industry pricing reference. Optimal Medical Group has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

What to Expect at Your First Optimal Medical Group Appointment

1. Initial intake call — Brief medical history review, depression and anxiety screening, and medical clearance for IV ketamine. Call (559) 840-0066 to schedule.
2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Optimal Medical Group clinical team.
3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 7206 N Milburn Avenue, #106, Fresno, CA 93722. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your Optimal Medical Group Consult Call

• How long has the Optimal Medical Group clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
• Does Optimal Medical Group provide a superbill for out-of-network insurance reimbursement, and what’s a typical 6-session total cost including any follow-up?
• California’s psychedelic-therapy regulatory landscape is evolving — do you stay current with state Department of Public Health and Medical Board guidance on ketamine prescribing?
• What does Optimal Medical Group recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about Optimal Medical Group

This 4-question summary is matched to the protocols and conditions Optimal Medical Group treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Is Optimal Medical Group suited for treatment-resistant depression?

Optimal Medical Group treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Optimal Medical Group treat chronic pain conditions?

Yes — Optimal Medical Group treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does Optimal Medical Group treat PTSD?

Yes — Optimal Medical Group treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Optimal Medical Group help with anxiety disorders?

Yes — Optimal Medical Group treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

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