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Additional resource: The National Institute of Mental Health (NIMH) provides comprehensive information about depression treatment options.
Learn more about this treatment:
- Silo Pharma is Developing a Ketamine Implant for Pain Management
- Low-dose Ketamine Shows Promise for Pain Relief in ER Patients
Patient Questions about Optimum Wellness & TMS
This 2-question summary is matched to the protocols and conditions Optimum Wellness & TMS treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Does Optimum Wellness & TMS offer Spravato (esketamine)?
Yes — Optimum Wellness & TMS offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.
Is Optimum Wellness & TMS suited for treatment-resistant depression?
Optimum Wellness & TMS treats depression via Spravato (FDA-approved for TRD). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
View all REMS-certified Spravato clinics in OH and across the United States.
Learn more about this treatment:
- Insurance Coverage for Ketamine Therapy in 2026: What Patients and Providers Need to Know
- October 2025 Roundup: What Ketamine Treatment Costs Across the United States
✓ Last verified: February 19, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Downtown Columbus’s dedicated Spravato and TMS center, offering two of the most evidence-backed interventional treatments for treatment-resistant depression under one roof.
| Google Reviews | Google Reviews: Check Google for latest ratings |
| Location | Columbus, OH |
| Address | 500 E Main Street, Suites 110 & 130, Columbus, OH 43215 |
| Phone | (614) 933-4200 |
| Website | optimumwellnessandtms.com |
| Treatments | Spravato (esketamine, REMS-certified), TMS |
| Conditions | Treatment-resistant depression, OCD |
| Cost | Contact clinic |
| Insurance | Spravato typically covered by insurance (FDA-approved) |
| KAP Available? | No |
| Clinical Lead | Optimum Wellness clinical team |
HealingMaps Take: Optimum Wellness fills a clear gap in central Columbus by pairing Spravato—the only FDA-approved nasal esketamine—with transcranial magnetic stimulation. Because Spravato carries FDA approval for treatment-resistant depression, most commercial insurers and Medicare plans cover it, removing the out-of-pocket barrier that keeps many patients away from ketamine therapy. The clinic’s East Main Street location puts it within walking distance of downtown offices and public transit, making the required two-hour post-dose monitoring period easier to schedule around a workday.
Market Position: Optimum Wellness & TMS is a Spravato-certified clinic in the metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.
Is Optimum Wellness & TMS Right for You?
✓ Choose Optimum Wellness & TMS if:
- You have commercial insurance and a documented treatment-resistant depression diagnosis (Spravato pathway)
✗ Look elsewhere if:
- You’re seeking cash-pay IV ketamine instead of insurance-billed Spravato
- You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy
- You need same-week appointments — Spravato prior authorization typically takes 1–3 weeks
Optimum Wellness & TMS Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$525–$900
Range: $450–$1,500/session
Estimated total program
$3,150–$5,400
Range: $2,700–$9,000/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at Optimum Wellness & TMS
Industry pricing reference. Optimum Wellness & TMS has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | — |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First Optimum Wellness & TMS Appointment
- Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check.
- Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Optimum Wellness & TMS clinical team.
- First treatment session — supervised Spravato (intranasal esketamine) in a private treatment room, lasting approximately 90 minutes (40-minute session + 60 minutes monitoring). Sessions are held at 500 E Main Street, Suites 110 & 130, Columbus, OH 43215. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your Spravato session.
What to Ask on Your Optimum Wellness & TMS Consult Call
- How long has the Optimum Wellness & TMS clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- How long does Optimum Wellness & TMS’s Spravato prior authorization typically take with my specific insurance plan, and what happens if it’s denied?
- How is the two-hour REMS monitoring period structured — quiet recovery room, group setting, or staff observation?
- What does Optimum Wellness & TMS recommend for patients who don’t respond to the standard 6-session acute series?
Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Franklin County, , crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Franklin County, : 25.6%
- Frequent mental distress (14+ days per month): 18.1%
- Adults lacking health insurance: 8.3%
- Franklin County population: 1,318,149 · median household income $71,070
- Recent -area inquiries to HealingMaps: A growing stream of residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
Telehealth ketamine programs undercut in-clinic pricing by 40–60%, but 64.8% of surveyed patients still prefer supervised in-clinic treatment — a clear cost-vs-safety tradeoff patients should weigh before choosing an at-home program. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“I had tried multiple antidepressants over the years with no real improvement. After my first few Spravato sessions here, I felt a shift I hadn’t experienced in a decade.” — Patient via clinic feedback
About Optimum Wellness & TMS
Optimum Wellness & TMS operates from a purpose-built suite in downtown Columbus focused exclusively on interventional psychiatry. The practice administers Spravato under the FDA’s REMS certification program, meaning patients receive each dose on-site and are monitored for at least two hours before discharge. TMS is offered as a standalone treatment or in combination with Spravato for patients whose depression has not responded to oral medication. The clinical team coordinates with each patient’s referring psychiatrist or primary-care provider to track progress using standardized depression scales.
New to ketamine therapy? Read our comprehensive guide: What Is Ketamine Therapy?
What People Like
- Insurance-friendly Spravato pathway removes cost uncertainty
- central downtown location near public transit
- structured REMS monitoring provides built-in safety net
- TMS available as a complementary modality.
What People Don’t Like
- Does not offer IV ketamine or oral ketamine options
- limited to depression and OCD (not chronic pain)
- monitoring requirement means appointments run at least two hours.
Getting Started
Call (614) 933-4200 to schedule an initial evaluation. Your referring provider will need to document prior medication trials to confirm treatment-resistant depression, which is required for Spravato eligibility. The clinic’s intake coordinator can walk you through insurance pre-authorization.
Additional resource: The National Institute of Mental Health (NIMH) provides comprehensive information about depression treatment options.
Learn more about this treatment:
- Silo Pharma is Developing a Ketamine Implant for Pain Management
- Low-dose Ketamine Shows Promise for Pain Relief in ER Patients
Patient Questions about Optimum Wellness & TMS
This 2-question summary is matched to the protocols and conditions Optimum Wellness & TMS treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Does Optimum Wellness & TMS offer Spravato (esketamine)?
Yes — Optimum Wellness & TMS offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.
Is Optimum Wellness & TMS suited for treatment-resistant depression?
Optimum Wellness & TMS treats depression via Spravato (FDA-approved for TRD). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
View all REMS-certified Spravato clinics in OH and across the United States.
Learn more about this treatment:
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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