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✓ Last verified: February 24, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Southern Maine’s most comprehensive interventional psychiatry suite — IV ketamine, Spravato, and TMS — led by a co-founding team of a psychiatrist, CRNA, and psychiatric NP.

Review ScoresContact clinic for reviews
LocationYork, ME
Address4 Market Place Dr, Suite 1-2, York, ME 03909
Phone(207) 630-2922
Websiteriseimh.com
TreatmentsIV Ketamine Infusions, Spravato (Esketamine), TMS, Psychiatric Medication Management, Psychotherapy, Group Therapy
Conditions TreatedDepression, Anxiety, PTSD, OCD, Treatment-Resistant Depression
Cost$800 per IV ketamine infusion
InsuranceSpravato and TMS may be covered by insurance; IV ketamine is self-pay
Clinical LeadDr. Amanda Sedgewick (Psychiatrist), Julie Kelbert, CRNA, and Alison Tetrault, PMHNP — Co-Founders

HealingMaps Take: R.I.S.E. Integrated Mental Health is the most complete interventional psychiatry practice in southern Maine. Co-founded by Dr. Amanda Sedgewick (psychiatrist), Julie Kelbert (CRNA), and Alison Tetrault (PMHNP), the practice offers the full trifecta of IV ketamine, Spravato, and TMS under one roof — a combination that is exceptionally rare outside of academic medical centers. The York location at 4 Market Place Dr serves the entire southern Maine and Seacoast NH corridor, from Kittery to Kennebunkport. At $800 per IV ketamine infusion, pricing is transparent and competitive for the New England market. The co-founding team structure is notable: a psychiatrist for diagnostic oversight, a CRNA for safe infusion administration, and a psychiatric NP for ongoing medication management. This multi-disciplinary model means patients receive care from specialists at every stage of treatment. The addition of group therapy programming further distinguishes RISE from standalone infusion clinics.

Market Position: R.I.S.E. Integrated Mental Health is a Spravato-certified clinic in the York metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.

Is R.I.S.E. Integrated Mental Health Right for You?

✓ Choose R.I.S.E. Integrated Mental Health if:

  • You have commercial insurance and a documented treatment-resistant depression diagnosis (Spravato pathway)
  • You want supervised IV ketamine with real-time medical monitoring
  • You want academic-medical-center protocols and clinical-trial-grade oversight
  • You’re treating co-occurring depression and PTSD

✗ Look elsewhere if:

  • You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy
  • You need same-week appointments — Spravato prior authorization typically takes 1–3 weeks
  • You’re seeking ketamine for chronic pain (this clinic focuses on mental health)

Ketamine Protocols Compared — What’s Offered at R.I.S.E. Integrated Mental Health

Industry pricing reference. R.I.S.E. Integrated Mental Health’s posted price: $800 per IV ketamine infusion. Contact the clinic for any package or sliding-scale options. The calculator above shows metro-level cost estimates across protocols.

ProtocolTypical Industry CostOffered Here
IV Ketamine$350–$650/session✓ Yes
Spravato (esketamine)$0–$250 copay (insured)✓ Yes
IM Ketamine$250–$400/injection—
KAP (with therapist)$400–$1,200/session—
At-home troches$150–$300/month—

What to Expect at Your First R.I.S.E. Integrated Mental Health Appointment

  1. Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Call (207) 630-2922 to schedule. R.I.S.E. Integrated Mental Health’s posted pricing: $800 per IV ketamine infusion.
  2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the R.I.S.E. Integrated Mental Health clinical team.
  3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 4 Market Place Dr, Suite 1-2, York, ME 03909. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
  4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your R.I.S.E. Integrated Mental Health Consult Call

  • How long has the R.I.S.E. Integrated Mental Health clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
  • Walk me through R.I.S.E. Integrated Mental Health’s Spravato prior authorization process versus your IV ketamine cash-pay or superbill workflow — which is the better fit for my insurance situation?
  • Does R.I.S.E. Integrated Mental Health require a referral from a current treating psychiatrist, and how do you handle outside-prescriber medication-management coordination?
  • What does R.I.S.E. Integrated Mental Health recommend for patients who don’t respond to the standard 6-session acute series?

York Ketamine Market Snapshot

Sources: CDC PLACES 2023 (York County, ME, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.

  • Adult depression in York County, ME: 25.4%
  • Frequent mental distress (14+ days per month): 18.7%
  • Adults lacking health insurance: 7.3%
  • York County population: 212,691 · median household income $79,743
  • Recent York-area inquiries to HealingMaps: A growing stream of Maine residents have recently contacted us seeking ketamine care

Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.

From the 2026 Ketamine Industry Report

23.8% of ketamine inquiries to HealingMaps arrive between midnight and 6 AM — a late-night pattern that underscores how often treatment-resistant depression symptoms peak when clinics are closed. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.

Patient Questions about R.I.S.E. Integrated Mental Health

This 5-question summary is matched to the protocols and conditions R.I.S.E. Integrated Mental Health treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

What ketamine protocols does R.I.S.E. Integrated Mental Health offer?

R.I.S.E. Integrated Mental Health offers Spravato and IV ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.

Does R.I.S.E. Integrated Mental Health offer Spravato (esketamine)?

Yes — R.I.S.E. Integrated Mental Health offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.

Is R.I.S.E. Integrated Mental Health suited for treatment-resistant depression?

R.I.S.E. Integrated Mental Health treats depression via Spravato (FDA-approved for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does R.I.S.E. Integrated Mental Health treat PTSD?

Yes — R.I.S.E. Integrated Mental Health treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can R.I.S.E. Integrated Mental Health help with anxiety disorders?

Yes — R.I.S.E. Integrated Mental Health treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

View all REMS-certified Spravato clinics in Maine and across the United States.

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Healing Maps Editorial Staff

Healing Maps Editorial Staff

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The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

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