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✓ Last verified: March 23, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Colorado Springs (E Woodmen Rd, Powers corridor) location of the multi-state Serenity Mental Health Centers network. IV ketamine + Spravato + TMS + psychiatric care. Standardized chain protocols across AZ/UT/CO/TX/FL/NV locations.
| Location | Colorado Springs, Colorado |
| Address | 6071 East Woodmen Road, Suite 200, Colorado Springs, CO 80923 |
| Phone | (719) 212-4401 |
| Website | serenitymentalhealthcenters.com |
| Treatments | IV Ketamine + Spravato (Esketamine) + TMS + Psychiatric Care |
| Conditions | Depression, anxiety, ADHD, bipolar disorder, OCD, PTSD |
| Cost | N/A (contact for pricing) |
| Insurance | Spravato typically insurance-billed; IV ketamine self-pay (FSA/HSA eligible) |
| KAP Available | No |
| Clinical Lead | Serenity Mental Health Centers clinical team (multi-state psychiatry network — Dr. Matthew Mills, DO among Colorado providers) |
HealingMaps Take: Serenity brings its multi-state network depth to northeast Colorado Springs — meaningful for Powers-corridor and Briargate patients who want the standardized protocols, insurance workflows, and TMS + ketamine + Spravato stack the chain runs across its AZ/UT/CO/TX/FL/NV footprint. The network model means prior-auth and Spravato REMS workflows are well-oiled.
Market Position: Serenity occupies the national-network slot in Colorado Springs — distinct from local independents (Colorado Ketamine, Springs Ketamine Infusions) and regional Southern Colorado TMS. Network-scale insurance workflow depth is their differentiator; local-roots patients may prefer the independents.
Is Serenity Mental Health Right for You?
✓ Choose Serenity Mental Health if:
- You want a national network’s standardized protocols and insurance workflow depth
- You’re in northeast Colorado Springs (Powers corridor, Briargate, Falcon)
- You want IV ketamine, Spravato, AND TMS under one roof
- Insurance-billable Spravato is your preferred entry modality
- You’ve had good experiences with Serenity locations in other states
✗ Look elsewhere if:
- You prefer a locally-owned independent practice
- You’re seeking ketamine-assisted psychotherapy (KAP)
- You’re on the west side (Sinton Rd / Southern Colorado TMS is closer)
Serenity Mental Health Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$416–$714
Range: $357–$1,190/session
Estimated total program
$2,499–$4,283
Range: $2,142–$7,139/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at Serenity Mental Health
Industry pricing reference. Serenity Mental Health has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First Serenity Mental Health Appointment
- Initial intake call — Insurance verification, Spravato prior authorization workflow if applicable, and clinical eligibility check. Call (719) 212-4401 to schedule.
- Medical evaluation — psychiatric assessment, vitals check, and review of current medications and prior treatment history with the Serenity Mental Health clinical team.
- First treatment session — supervised ketamine session in a monitored treatment room at 6071 East Woodmen Road, Suite 200, Colorado Springs, CO 80923.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session.
What to Ask on Your Serenity Mental Health Consult Call
- How long has the Serenity Mental Health clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- Walk me through your Spravato prior authorization process vs. IV ketamine cash-pay workflow — which is the better fit for my insurance situation?
- What is your specific ketamine protocol (dose, sessions, monitoring), and how do you decide when to recommend booster sessions?
- How do you handle patients who don’t respond to the standard induction series?
Colorado Springs Ketamine Market Snapshot
Sources: CDC PLACES 2023 (El Paso County (Colorado Springs metro NE), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in El Paso County (Colorado Springs metro NE): 16.7%
- Frequent mental distress (14+ days per month): 13.4%
- Adults lacking health insurance: 8.7%
- El Paso County (Colorado Springs metro NE) population: 740,567 · median household income $74,754
- Recent Colorado Springs-area inquiries to HealingMaps: A growing stream of Colorado Springs-area residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,800 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“Serenity’s insurance team got my Spravato prior auth approved in nine days — my previous independent clinic had been stuck on it for two months. The network machinery actually matters.”
About Serenity Mental Health
Serenity Mental Health Centers’ Colorado Springs office operates from 6071 East Woodmen Road, Suite 200 (80923) — northeast Colorado Springs location on the Powers corridor, accessible from Briargate, Falcon, and northern El Paso County. The practice is part of the multi-state Serenity network spanning Arizona, Utah, Colorado, Texas, Florida, and Nevada.
The modality stack covers IV ketamine, Spravato (esketamine) under FDA REMS certification, TMS therapy, and comprehensive psychiatric care. The network model means standardized treatment protocols and well-established insurance prior-authorization workflows — often the practical difference between starting Spravato in two weeks versus two months.
Conditions treated include depression, anxiety, ADHD, bipolar disorder, OCD, and PTSD. Dr. Matthew Mills, DO is among the Colorado provider team.
To schedule, call (719) 212-4401 or visit serenitymentalhealthcenters.com.
Patient Questions about Serenity Mental Health
This 5-question summary is matched to the protocols and conditions Serenity Mental Health treats. Editorial responses are HealingMaps-authored.
What ketamine protocols does Serenity Mental Health offer?
Serenity Mental Health offers IV Ketamine + Spravato (Esketamine) + TMS + Psychiatric Care. Confirm specific dosing schedules during your consult.
Does Serenity Mental Health offer Spravato (esketamine)?
Yes — Serenity Mental Health offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose.
Does Serenity Mental Health offer ketamine-assisted psychotherapy (KAP)?
Serenity Mental Health operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
Is Serenity Mental Health suited for treatment-resistant depression?
Serenity Mental Health treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Can Serenity Mental Health help with anxiety disorders?
Yes — Serenity Mental Health treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in Colorado and across the United States.
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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