✓ Last verified: January 20, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Serenity Mental Health Centers’ Cherry Creek location brings comprehensive psychiatric care to Denver’s Cherry Creek neighborhood. The clinic offers ketamine infusion therapy for treatment-resistant depression alongside TMS therapy, medication management, and psychotherapy. With extended weekday and Saturday hours, the Cherry Creek office provides flexible scheduling for working professionals seeking mental health treatment.
| Google Reviews | ⭐ 4.0 stars (546 reviews across locations) |
| Location | Cherry Creek, Denver, Colorado |
| Address | 425 S Cherry St, Ste. 620, Denver, CO 80246 |
| Phone | (720) 306-9570 |
| Website | serenitymentalhealthcenters.com |
| Treatments | Ketamine Infusion Therapy, TMS Therapy, Medication Management, Psychotherapy, ADHD Testing |
| Conditions Treated | Treatment-Resistant Depression, Anxiety, PTSD, ADHD, OCD, Bipolar Disorder, Chronic Pain |
| Cost | Ketamine is cash pay only – Payment plans available |
| Insurance | Accepted for psychiatry & therapy (Aetna, Cigna, and more) – Ketamine is cash pay |
| KAP Available | Ketamine infusions offered – Contact for KAP availability |
| Clinical Lead | Multi-provider team including NPs and psychiatrists |
HealingMaps Take: The Cherry Creek location offers the same comprehensive Serenity Mental Health platform in a convenient Denver neighborhood with Saturday availability — a real plus for busy schedules. The practice accepts a broad range of insurance plans for psychiatry and therapy services, though ketamine infusions remain cash pay. With 4 stars across 500+ reviews system-wide, patient feedback is generally positive, with appreciation for the collaborative care model. This location is well-suited for patients who want ketamine therapy integrated with ongoing psychiatric treatment rather than as a standalone service.
Market Position: Serenity Mental Health treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.
⚠ FDA-cleared indications for TMS therapy: treatment-resistant major depressive disorder (MDD), obsessive-compulsive disorder (OCD, Deep TMS only), anxious depression, short-term smoking cessation, and adolescent MDD (ages 15–21). Use of TMS for other conditions including PTSD, bipolar depression, fibromyalgia, and other indications is off-label — not currently FDA-cleared for those specific indications. Discuss your condition with the clinic to understand insurance coverage and clinical evidence.
Industry pricing reference. Serenity Mental Health has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine Infusion | $350–$650/session | ✓ |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| TMS (transcranial magnetic stimulation) | $200–$300/session, often insurance-covered | ✓ |
| IM Ketamine | $250–$400/injection | — |
| KAP (with integrated talk therapy) | $400–$1,200/session | ✓ |
| At-home oral troches | $150–$300/month | — |
Sources: CDC PLACES 2023 (Denver County, CO, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
Depression is the #1 condition cited in 20.9% of HealingMaps ketamine inquiries, followed by PTSD (13.5%) and anxiety (11.4%) — the three together account for nearly half of all patient demand. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
This 2-question summary is matched to the protocols and conditions Serenity Mental Health treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Yes — Serenity Mental Health treats chronic pain. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — Serenity Mental Health treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
This clinic also offers TMS therapy alongside ketamine. TMS sessions take 19 to 37 minutes (or 3 minutes for the iTBS protocol), with no anesthesia, sedation, or controlled-substance handling. This clinic uses BrainsWay Deep TMS, the only TMS device with standalone FDA clearance for OCD via the H7 coil. Read our complete guide to TMS therapy for FDA-cleared conditions, device differences, insurance coverage by carrier, and what to expect at your first appointment. Browse verified TMS clinics in our directory.
Marjorie comer
March 27, 2022 at 12:52 amHi- wondering if you do Med mgmt? Thx
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