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✓ Last verified: January 20, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Serenity Mental Health in Cherry Creek, Colorado logo

Known For: Serenity Mental Health Centers’ Cherry Creek location brings comprehensive psychiatric care to Denver’s Cherry Creek neighborhood. The clinic offers ketamine infusion therapy for treatment-resistant depression alongside TMS therapy, medication management, and psychotherapy. With extended weekday and Saturday hours, the Cherry Creek office provides flexible scheduling for working professionals seeking mental health treatment.

Google Reviews⭐ 4.0 stars (546 reviews across locations)
LocationCherry Creek, Denver, Colorado
Address425 S Cherry St, Ste. 620, Denver, CO 80246
Phone(720) 306-9570
Websiteserenitymentalhealthcenters.com
TreatmentsKetamine Infusion Therapy, TMS Therapy, Medication Management, Psychotherapy, ADHD Testing
Conditions TreatedTreatment-Resistant Depression, Anxiety, PTSD, ADHD, OCD, Bipolar Disorder, Chronic Pain
CostKetamine is cash pay only – Payment plans available
InsuranceAccepted for psychiatry & therapy (Aetna, Cigna, and more) – Ketamine is cash pay
KAP AvailableKetamine infusions offered – Contact for KAP availability
Clinical LeadMulti-provider team including NPs and psychiatrists

HealingMaps Take: The Cherry Creek location offers the same comprehensive Serenity Mental Health platform in a convenient Denver neighborhood with Saturday availability — a real plus for busy schedules. The practice accepts a broad range of insurance plans for psychiatry and therapy services, though ketamine infusions remain cash pay. With 4 stars across 500+ reviews system-wide, patient feedback is generally positive, with appreciation for the collaborative care model. This location is well-suited for patients who want ketamine therapy integrated with ongoing psychiatric treatment rather than as a standalone service.

Market Position: Serenity Mental Health treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.

Is Serenity Mental Health Right for You?

✓ Choose Serenity Mental Health if:

  • You’re treating co-occurring depression and PTSD

✗ Look elsewhere if:

  • You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy
  • You need insurance billing for treatment (this clinic is cash-pay)

Serenity Mental Health Ketamine Cost Calculator

How Much Will Ketamine Therapy Cost?

Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$525–$900
Range: $450–$1,500/session
Estimated total program
$3,150–$5,400
Range: $2,700–$9,000/6-session series
Your estimate vs. national patient-reported median Based on national tracking, adjusted for Manhattan, NY market
Select a treatment type to see pricing context.

⚠ FDA-cleared indications for TMS therapy: treatment-resistant major depressive disorder (MDD), obsessive-compulsive disorder (OCD, Deep TMS only), anxious depression, short-term smoking cessation, and adolescent MDD (ages 15–21). Use of TMS for other conditions including PTSD, bipolar depression, fibromyalgia, and other indications is off-label — not currently FDA-cleared for those specific indications. Discuss your condition with the clinic to understand insurance coverage and clinical evidence.

Ketamine Protocols Compared — What’s Offered at Serenity Mental Health

Industry pricing reference. Serenity Mental Health has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

ProtocolTypical Industry CostOffered Here
IV Ketamine Infusion$350–$650/session
Spravato (esketamine)$0–$250 copay (insured)
TMS (transcranial magnetic stimulation)$200–$300/session, often insurance-covered
IM Ketamine$250–$400/injection
KAP (with integrated talk therapy)$400–$1,200/session
At-home oral troches$150–$300/month

What to Expect at Your First Serenity Mental Health Appointment

  1. Initial intake call — Medical history review and clinical eligibility check. Call (720) 306-9570 to schedule. Serenity Mental Health’s posted pricing: Ketamine is cash pay only – Payment plans available.
  2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Serenity Mental Health clinical team.
  3. First treatment session — supervised ketamine therapy session in a private treatment room, lasting approximately 60–90 minutes. Sessions are held at 425 S Cherry St, Ste. 620, Denver, CO 80246. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
  4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your ketamine session.

What to Ask on Your Serenity Mental Health Consult Call

  • How long has the Serenity Mental Health clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
  • What’s a typical 6-session total cost at Serenity Mental Health, and do you offer payment plans, HSA/FSA-eligible billing, or sliding-scale pricing?
  • Colorado’s Natural Medicine Health Act covers certain psychedelics — how does your ketamine practice integrate with broader psychedelic-therapy options patients may consider?
  • What does Serenity Mental Health recommend for patients who don’t respond to the standard 6-session acute series?

Creek Ketamine Market Snapshot

Sources: CDC PLACES 2023 (Denver County, CO, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.

  • Adult depression in Denver County, CO: 22.7%
  • Frequent mental distress (14+ days per month): 15.2%
  • Adults lacking health insurance: 12.1%
  • Denver County population: 710,800 · median household income $85,853
  • Recent Creek-area inquiries to HealingMaps: A growing stream of Colorado residents have recently contacted us seeking ketamine care

Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.

From the 2026 Ketamine Industry Report

Depression is the #1 condition cited in 20.9% of HealingMaps ketamine inquiries, followed by PTSD (13.5%) and anxiety (11.4%) — the three together account for nearly half of all patient demand. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.

Patient Questions about Serenity Mental Health

This 2-question summary is matched to the protocols and conditions Serenity Mental Health treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Does Serenity Mental Health treat chronic pain conditions?

Yes — Serenity Mental Health treats chronic pain. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does Serenity Mental Health treat PTSD?

Yes — Serenity Mental Health treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

This clinic also offers TMS therapy alongside ketamine. TMS sessions take 19 to 37 minutes (or 3 minutes for the iTBS protocol), with no anesthesia, sedation, or controlled-substance handling. This clinic uses BrainsWay Deep TMS, the only TMS device with standalone FDA clearance for OCD via the H7 coil. Read our complete guide to TMS therapy for FDA-cleared conditions, device differences, insurance coverage by carrier, and what to expect at your first appointment. Browse verified TMS clinics in our directory.

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  • Marjorie comer
    March 27, 2022 at 12:52 am

    Hi- wondering if you do Med mgmt? Thx

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Healing Maps Editorial Staff

Healing Maps Editorial Staff

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The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

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