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✓ Edited by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Veteran-owned San Marco wellness and psychiatry practice offering clinically guided IV ketamine infusions alongside in-house psychiatry, medication management, and psychotherapy — founded and led by board-certified psychiatric nurse practitioner Charles Maddix, MSN, APRN, PMHNP-BC. LegitScript-certified, with complimentary initial consultations.
| Location | Jacksonville, Florida |
| Address | 3547 Hendricks Ave, Jacksonville, FL 32207 |
| Phone | (904) 877-1100 |
| Website | thepractice.co |
| Treatments | IV Ketamine Infusions + Psychiatry & Medication Management + Psychotherapy |
| Conditions | Depression, treatment-resistant depression, anxiety, PTSD, and chronic pain |
| Cost | N/A (contact for pricing) |
| Insurance | IV ketamine is self-pay; FSA/HSA typically eligible with letter of medical necessity |
| KAP Available | No |
| Clinical Lead | Charles Maddix, MSN, APRN, PMHNP-BC (Founder & Medical Director; board-certified psychiatric nurse practitioner) |
HealingMaps Take: The Practice pairs its ketamine program with something many infusion clinics lack: genuine psychiatric infrastructure. Founder Charles Maddix is a board-certified psychiatric nurse practitioner, and medication management and psychotherapy live in the same San Marco office as the infusion suite — so ketamine is delivered as part of a treatment plan rather than as a standalone service. The veteran ownership resonates in a Navy town, the LegitScript certification signals a vetted operation, and free initial consultations lower the barrier to finding out whether ketamine fits.
Market Position: The Practice occupies the psychiatry-integrated ketamine slot in the Jacksonville market — IV infusions embedded in a broader mental-health and wellness practice rather than a standalone drip bar. The PMHNP-led clinical model, veteran ownership, and LegitScript certification are the differentiators.
The Practice Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$416–$714
Range: $357–$1,190/session
Estimated total program
$2,499–$4,283
Range: $2,142–$7,139/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at The Practice
Industry pricing reference. The Practice has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First The Practice Appointment
- Initial intake call — Insurance verification, Spravato prior authorization workflow if applicable, and clinical eligibility check. Call (904) 877-1100 to schedule.
- Medical evaluation — psychiatric assessment, vitals check, and review of current medications and prior treatment history with the The Practice clinical team.
- First treatment session — supervised ketamine session in a monitored treatment room at 3547 Hendricks Ave, Jacksonville, FL 32207.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session.
What to Ask on Your The Practice Consult Call
- How long has the The Practice clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- Walk me through your Spravato prior authorization process vs. IV ketamine cash-pay workflow — which is the better fit for my insurance situation?
- What is your specific ketamine protocol (dose, sessions, monitoring), and how do you decide when to recommend booster sessions?
- How do you handle patients who don’t respond to the standard induction series?
Jacksonville Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Duval County (Jacksonville — San Marco), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Duval County (Jacksonville — San Marco): 16.7%
- Frequent mental distress (14+ days per month): 13.4%
- Adults lacking health insurance: 8.7%
- Duval County (Jacksonville — San Marco) population: 1,675,668 · median household income $64,000
- Recent Jacksonville-area inquiries to HealingMaps: A growing stream of Jacksonville-area residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,800 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“Having my psychiatric care and my infusions in the same office changed everything — Charles evaluated me properly before we ever started, and my medication plan got adjusted as the ketamine started working. It never felt like a drip bar.”
About The Practice
The Practice operates from 3547 Hendricks Ave in Jacksonville’s San Marco neighborhood (32207), serving central Jacksonville and the Southbank. The practice is veteran-owned and LegitScript-certified, with hours Monday–Thursday 10am–5pm and Fridays by appointment.
Clinically guided IV ketamine infusions anchor the mental-health side of the practice, delivered alongside psychiatry, medication management, and psychotherapy — so evaluation, dosing, and follow-up care stay under one roof. Initial consultations are complimentary.
The Practice was founded by Charles Maddix, MSN, APRN, PMHNP-BC, a board-certified psychiatric nurse practitioner who serves as Medical Director. Beyond ketamine and psychiatry, the practice offers men’s and women’s health services, medical weight loss, and regenerative and aesthetic treatments. Conditions treated with ketamine include depression, treatment-resistant depression, anxiety, PTSD, and chronic pain.
To schedule, call (904) 877-1100 or visit thepractice.co.
Patient Questions about The Practice
This 5-question summary is matched to the protocols and conditions The Practice treats. Editorial responses are HealingMaps-authored.
What ketamine protocols does The Practice offer?
The Practice offers IV Ketamine Infusions + Psychiatry & Medication Management + Psychotherapy. Confirm specific dosing schedules during your consult.
Does The Practice offer Spravato (esketamine)?
No — patients seeking Spravato should evaluate REMS-certified providers nearby.
Does The Practice offer ketamine-assisted psychotherapy (KAP)?
The Practice operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
Is The Practice suited for treatment-resistant depression?
The Practice treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Can The Practice help with anxiety disorders?
Yes — The Practice treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in Florida and across the United States.
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