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✓ Last verified: March 23, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Rochester (Monroe Ave / Pittsford border) IV ketamine clinic — the first clinic to offer ketamine infusions in upstate New York. Dedicated infusion practice for complicated psychiatric disorders and chronic pain.
| Location | Rochester, New York |
| Address | 3300 Monroe Ave, Suite 345, Rochester, NY 14618 |
| Phone | (585) 673-2319 |
| Website | upstateketaminecenter.com |
| Treatments | IV Ketamine Infusion Therapy |
| Conditions | Treatment-resistant depression, complicated psychiatric disorders, chronic pain |
| Cost | N/A (contact for pricing) |
| Insurance | IV ketamine is self-pay; FSA/HSA typically eligible with letter of medical necessity |
| KAP Available | No |
| Clinical Lead | Upstate Ketamine Center clinical team |
HealingMaps Take: Upstate Ketamine Center’s ‘first in upstate New York’ credential carries real weight — practice depth and protocol experience accumulate, and Rochester patients comparing newer entrants should weigh that history. The dedicated IV-only model (no medspa services, no TMS distractions) drives infusion expertise. For a metro of 750K+ with no dedicated ketamine listing on HealingMaps until now, this is the anchor.
Market Position: Upstate Ketamine Center occupies the established dedicated-infusion slot in Rochester — the metro’s pioneering ketamine practice. Distinct from wellness/TRT practices (What the Wellness IV, Rochester TRT, Vitalize Medical) that offer IV services within broader menus.
Is Upstate Ketamine Center Right for You?
✓ Choose Upstate Ketamine Center if:
- You value the ‘first ketamine clinic in upstate NY’ practice depth
- You want a dedicated IV-ketamine-only practice (no medspa, no diversions)
- You have a complicated psychiatric presentation or chronic pain alongside depression
- You’re in Rochester, Pittsford, Brighton, Fairport, or Monroe County
- You’re self-pay or FSA/HSA-funded and want straightforward billing
✗ Look elsewhere if:
- You need Spravato (insurance-billable) — not offered here
- You’re seeking ketamine-assisted psychotherapy (KAP)
- You want IM or at-home options
Upstate Ketamine Center Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$416–$714
Range: $357–$1,190/session
Estimated total program
$2,499–$4,283
Range: $2,142–$7,139/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at Upstate Ketamine Center
Industry pricing reference. Upstate Ketamine Center has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First Upstate Ketamine Center Appointment
- Initial intake call — Insurance verification, Spravato prior authorization workflow if applicable, and clinical eligibility check. Call (585) 673-2319 to schedule.
- Medical evaluation — psychiatric assessment, vitals check, and review of current medications and prior treatment history with the Upstate Ketamine Center clinical team.
- First treatment session — supervised ketamine session in a monitored treatment room at 3300 Monroe Ave, Suite 345, Rochester, NY 14618.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session.
What to Ask on Your Upstate Ketamine Center Consult Call
- How long has the Upstate Ketamine Center clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- Walk me through your Spravato prior authorization process vs. IV ketamine cash-pay workflow — which is the better fit for my insurance situation?
- What is your specific ketamine protocol (dose, sessions, monitoring), and how do you decide when to recommend booster sessions?
- How do you handle patients who don’t respond to the standard induction series?
Rochester Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Monroe County (Rochester metro), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Monroe County (Rochester metro): 16.7%
- Frequent mental distress (14+ days per month): 13.4%
- Adults lacking health insurance: 8.7%
- Monroe County (Rochester metro) population: 752,035 · median household income $70,785
- Recent Rochester-area inquiries to HealingMaps: A growing stream of Rochester-area residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,800 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“Upstate Ketamine was doing infusions years before anyone else in Rochester — that experience showed in how they handled my dose titration when the standard protocol wasn’t working.”
About Upstate Ketamine Center
Upstate Ketamine Center operates from 3300 Monroe Ave, Suite 345 in Rochester (14618) — Monroe Avenue location near the Pittsford border, accessible from Rochester, Brighton, Pittsford, Fairport, and Monroe County. The practice was the first clinic to offer ketamine infusions in upstate New York.
The practice is a dedicated IV ketamine infusion center — no medspa services, no TMS, no broader wellness menu. That single focus concentrates protocol experience: IV ketamine for complicated psychiatric disorders and chronic pain, with relief potentially experienced within hours of infusion.
Rochester patients seeking Spravato (insurance-billable esketamine) or KAP will need to look at other providers; Upstate Ketamine Center’s value proposition is depth in the off-label IV pathway specifically.
To schedule, call (585) 673-2319 or visit upstateketaminecenter.com.
Patient Questions about Upstate Ketamine Center
This 5-question summary is matched to the protocols and conditions Upstate Ketamine Center treats. Editorial responses are HealingMaps-authored.
What ketamine protocols does Upstate Ketamine Center offer?
Upstate Ketamine Center offers IV Ketamine Infusion Therapy. Confirm specific dosing schedules during your consult.
Does Upstate Ketamine Center offer Spravato (esketamine)?
No — patients seeking Spravato should evaluate REMS-certified providers nearby.
Does Upstate Ketamine Center offer ketamine-assisted psychotherapy (KAP)?
Upstate Ketamine Center operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
Is Upstate Ketamine Center suited for treatment-resistant depression?
Upstate Ketamine Center treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Can Upstate Ketamine Center help with anxiety disorders?
Yes — Upstate Ketamine Center treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in New York and across the United States.
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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