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✓ Last verified: April 15, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: The first civilian TMS center in Hawaii, the first on Oahu to use pharmacogenomics, and a REMS-certified Spravato (esketamine) center — Hawaii’s most established interventional psychiatry practice.
| Review Scores | Pioneer in interventional psychiatry in Hawaii |
| Location | Honolulu, HI |
| Address | 1164 Bishop St, Suite 1611, Honolulu, HI 96813 |
| Phone | (808) 261-7792 |
| Website | apt-hi.com |
| Treatments | Spravato (Esketamine Nasal Spray, REMS-Certified), TMS/Theta Burst Stimulation, Psychiatry |
| Conditions Treated | Treatment-Resistant Depression, General Psychiatric Conditions |
| Cost | Contact clinic for pricing |
| Insurance | Accepts many insurance types (Spravato typically covered by insurance) |
| Clinical Lead | Psychiatric team (first civilian TMS center in Hawaii; first on Oahu to use pharmacogenomics) |
💡 No clinic-specific pricing posted? See our ketamine therapy cost guide for typical pricing ranges by treatment type and insurance pathways.
HealingMaps Take: Advanced Psychiatric Therapeutics (APT) is Hawaii’s interventional psychiatry pioneer. As the first civilian TMS center in the state and the first practice on Oahu to implement pharmacogenomic testing, APT has consistently been years ahead of the local market. Their REMS-certified Spravato program adds FDA-approved esketamine nasal spray to the arsenal, and because Spravato is typically covered by insurance, this is one of the few Hawaii practices where patients can access ketamine-class treatment without paying entirely out of pocket. The downtown Honolulu location at Bishop Street puts the clinic in the heart of the business district — convenient for working professionals who need lunchtime or after-work appointments. For patients who want the insurance coverage advantage of Spravato combined with the option to add TMS, APT offers the most established and insurance-friendly interventional psychiatry program in the state.
Market Position: Advanced Psychiatric Therapeutics is a Spravato-certified clinic in the Honolulu metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.
Is Advanced Psychiatric Therapeutics Right for You?
✓ Choose Advanced Psychiatric Therapeutics if:
- You have commercial insurance and a documented treatment-resistant depression diagnosis (Spravato pathway)
✗ Look elsewhere if:
- You’re seeking cash-pay IV ketamine instead of insurance-billed Spravato
- You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy
- You need same-week appointments — Spravato prior authorization typically takes 1–3 weeks
Advanced Psychiatric Therapeutics Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$525–$900
Range: $450–$1,500/session
Estimated total program
$3,150–$5,400
Range: $2,700–$9,000/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at Advanced Psychiatric Therapeutics
Industry pricing reference. Advanced Psychiatric Therapeutics has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | — |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First Advanced Psychiatric Therapeutics Appointment
- Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Call (808) 261-7792 to schedule.
- Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Advanced Psychiatric Therapeutics clinical team.
- First treatment session — supervised Spravato (intranasal esketamine) in a private treatment room, lasting approximately 90 minutes (40-minute session + 60 minutes monitoring). Sessions are held at 1164 Bishop St, Suite 1611, Honolulu, HI 96813. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your Spravato session.
What to Ask on Your Advanced Psychiatric Therapeutics Consult Call
- How long has the Advanced Psychiatric Therapeutics clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- How long does Advanced Psychiatric Therapeutics’s Spravato prior authorization typically take with my specific insurance plan, and what happens if it’s denied?
- How is the two-hour REMS monitoring period structured — quiet recovery room, group setting, or staff observation?
- What does Advanced Psychiatric Therapeutics recommend for patients who don’t respond to the standard 6-session acute series?
Honolulu Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Honolulu County, HI, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Honolulu County, HI: 15.1%
- Frequent mental distress (14+ days per month): 15.3%
- Adults lacking health insurance: 5.2%
- Honolulu County population: 1,010,100 · median household income $99,816
- Recent Honolulu-area inquiries to HealingMaps: A growing stream of Hawaii residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
58.1% of patients say telehealth increases access to ketamine therapy — even among those skeptical of at-home protocols, virtual consultation consistently ranks as a net positive. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Questions about Advanced Psychiatric Therapeutics
This 2-question summary is matched to the protocols and conditions Advanced Psychiatric Therapeutics treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Does Advanced Psychiatric Therapeutics offer Spravato (esketamine)?
Yes — Advanced Psychiatric Therapeutics offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.
Is Advanced Psychiatric Therapeutics suited for treatment-resistant depression?
Advanced Psychiatric Therapeutics treats depression via Spravato (FDA-approved for TRD). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
View all REMS-certified Spravato clinics in Hawaii and across the United States.
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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