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✓ Last verified: March 23, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Columbia (Laurel St) IV ketamine clinic operating since 2014 — more than 1,300 patients treated and over 15,000 ketamine infusions administered, which the practice cites as the most experience of any center in the Southeast. Charleston sister location extends statewide coverage.
| Location | Columbia, South Carolina |
| Address | 2601 Laurel St, Suite 120, Columbia, SC 29204 |
| Phone | (803) 250-7171 |
| Website | columbiaketamineclinic.com |
| Treatments | IV Ketamine Infusion Therapy |
| Conditions | Treatment-resistant depression, anxiety, PTSD, mood disorders, chronic pain |
| Cost | N/A (contact for pricing) |
| Insurance | IV ketamine is self-pay; FSA/HSA typically eligible with letter of medical necessity |
| KAP Available | No |
| Clinical Lead | Columbia Ketamine Center clinical team |
HealingMaps Take: Columbia Ketamine Center’s volume credentials are extraordinary for the market — 15,000+ infusions since 2014 is more protocol experience than most multi-state chains accumulate. In a field where dosing refinement comes from reps, that depth matters for complex or treatment-resistant cases. The Charleston sister location makes this a two-city South Carolina institution.
Market Position: Columbia Ketamine Center occupies the established high-volume infusion slot in Columbia — the metro’s most experienced dedicated practice by a wide margin. Distinct from Future Psych Solutions’ psychiatry-led IV + Spravato model.
Is Columbia Ketamine Center Right for You?
✓ Choose Columbia Ketamine Center if:
- You want the deepest infusion experience in the Southeast (15,000+ infusions since 2014)
- You have a complex or treatment-resistant presentation where dose-titration experience matters
- You’re in Columbia, Forest Acres, Lexington SC, or the Midlands
- You want a dedicated IV-only practice
- You may also use their Charleston sister location
✗ Look elsewhere if:
- You need Spravato (insurance-billable) — Future Psych Solutions is adding it
- You’re seeking ketamine-assisted psychotherapy (KAP)
- You want a psychiatry-led practice with medication management
Columbia Ketamine Center Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$416–$714
Range: $357–$1,190/session
Estimated total program
$2,499–$4,283
Range: $2,142–$7,139/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at Columbia Ketamine Center
Industry pricing reference. Columbia Ketamine Center has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First Columbia Ketamine Center Appointment
- Initial intake call — Insurance verification, Spravato prior authorization workflow if applicable, and clinical eligibility check. Call (803) 250-7171 to schedule.
- Medical evaluation — psychiatric assessment, vitals check, and review of current medications and prior treatment history with the Columbia Ketamine Center clinical team.
- First treatment session — supervised ketamine session in a monitored treatment room at 2601 Laurel St, Suite 120, Columbia, SC 29204.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session.
What to Ask on Your Columbia Ketamine Center Consult Call
- How long has the Columbia Ketamine Center clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- Walk me through your Spravato prior authorization process vs. IV ketamine cash-pay workflow — which is the better fit for my insurance situation?
- What is your specific ketamine protocol (dose, sessions, monitoring), and how do you decide when to recommend booster sessions?
- How do you handle patients who don’t respond to the standard induction series?
Columbia Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Richland County (Columbia SC metro), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Richland County (Columbia SC metro): 16.7%
- Frequent mental distress (14+ days per month): 13.4%
- Adults lacking health insurance: 8.7%
- Richland County (Columbia SC metro) population: 829,470 · median household income $62,542
- Recent Columbia-area inquiries to HealingMaps: A growing stream of Columbia-area residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,800 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“Columbia Ketamine Center had seen cases like mine hundreds of times — after two failed attempts at newer clinics, their dose adjustments from a decade of experience finally got me to remission.”
About Columbia Ketamine Center
Columbia Ketamine Center operates from 2601 Laurel St, Suite 120 in Columbia, SC (29204) — accessible from Columbia, Forest Acres, Lexington, and the Midlands region. The practice has operated since 2014, making it one of the earliest dedicated ketamine clinics in the Southeast.
The volume numbers distinguish the practice: more than 1,300 patients treated and over 15,000 ketamine infusions administered — cited as the most experience of any ketamine center in the Southeast. In a field where dosing protocols are refined through repetition, that institutional experience is the practice’s core asset.
A sister location in Charleston (Charleston Ketamine Center) extends coverage across South Carolina’s two largest metros. The practice model is dedicated IV ketamine infusion — patients seeking Spravato or KAP will need to evaluate other Columbia providers.
Hours are Monday-Friday 10 AM – 5 PM (closed weekends). To schedule, call (803) 250-7171 or visit columbiaketamineclinic.com.
Patient Questions about Columbia Ketamine Center
This 5-question summary is matched to the protocols and conditions Columbia Ketamine Center treats. Editorial responses are HealingMaps-authored.
What ketamine protocols does Columbia Ketamine Center offer?
Columbia Ketamine Center offers IV Ketamine Infusion Therapy. Confirm specific dosing schedules during your consult.
Does Columbia Ketamine Center offer Spravato (esketamine)?
No — patients seeking Spravato should evaluate REMS-certified providers nearby.
Does Columbia Ketamine Center offer ketamine-assisted psychotherapy (KAP)?
Columbia Ketamine Center operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
Is Columbia Ketamine Center suited for treatment-resistant depression?
Columbia Ketamine Center treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Can Columbia Ketamine Center help with anxiety disorders?
Yes — Columbia Ketamine Center treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in South Carolina and across the United States.
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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