✓ Last verified: January 22, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Greenbrook TMS Mission Valley is centrally located in San Diego’s Mission Valley neighborhood on Frazee Road, offering insurance-covered Spravato (esketamine nasal spray) and NeuroStar TMS therapy. This location serves patients from central San Diego, Mission Hills, Hillcrest, North Park, and Kensington with FDA-approved treatments for treatment-resistant depression and MDD with suicidal ideation. As one of two Greenbrook locations in the San Diego metro, it provides a convenient central option for patients seeking insurance-covered ketamine-based treatment.
Treatment-Resistant Depression, MDD with Suicidal Ideation
Cost
Covered by most major insurance plans
Insurance
Most major insurance accepted for both Spravato and TMS
KAP Available
No — Spravato administered under medical supervision (not KAP)
Clinical Lead
Greenbrook TMS Clinical Team
HealingMaps Take: Mission Valley’s central location makes this Greenbrook office one of the most accessible in San Diego, with easy freeway access from nearly any part of the city. For patients who need insurance-covered Spravato treatment, having two San Diego Greenbrook locations (this one and Shoreham) means more scheduling flexibility and shorter wait times. The Mission Valley office is ideal for patients in the urban core of San Diego who want to combine treatment visits with other errands in this commercial hub.
Market Position: Greenbrook TMS (Mission Valley) is a Spravato-certified clinic in the Diego metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.
Is Greenbrook TMS (Mission Valley) Right for You?
✓ Choose Greenbrook TMS (Mission Valley) if:
You have commercial insurance and a documented treatment-resistant depression diagnosis (Spravato pathway)
✗ Look elsewhere if:
You’re seeking cash-pay IV ketamine instead of insurance-billed Spravato
You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy
You need same-week appointments — Spravato prior authorization typically takes 1–3 weeks
⚠ FDA-cleared indications for TMS therapy: treatment-resistant major depressive disorder (MDD), obsessive-compulsive disorder (OCD, Deep TMS only), anxious depression, short-term smoking cessation, and adolescent MDD (ages 15–21). Use of TMS for other conditions including PTSD, bipolar depression, fibromyalgia, and other indications is off-label — not currently FDA-cleared for those specific indications. Discuss your condition with the clinic to understand insurance coverage and clinical evidence.
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$525–$900
Range: $450–$1,500/session
Estimated total program
$3,150–$5,400
Range: $2,700–$9,000/6-session series
Your estimate vs. national patient-reported medianBased on national tracking, adjusted for San Diego, CA market
Select a treatment type to see pricing context.
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A HealingMaps specialist will follow up within one business day with providers that match your estimate, protocol, and insurance situation.
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Industry pricing reference. Greenbrook TMS (Mission Valley)’s posted price: Covered by most major insurance plans. Contact the clinic for any package or sliding-scale options. The calculator above shows metro-level cost estimates across protocols.
Protocol
Typical Industry Cost
Offered Here
IV Ketamine
$350–$650/session
—
Spravato (esketamine)
$0–$250 copay (insured)
✓ Yes
IM Ketamine
$250–$400/injection
—
KAP (with therapist)
$400–$1,200/session
—
At-home troches
$150–$300/month
—
What to Expect at Your First Greenbrook TMS (Mission Valley) Appointment
Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Call (855) 940-4867 or visit greenbrooktms.com to schedule. Greenbrook TMS (Mission Valley)’s posted pricing: Covered by most major insurance plans.
Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Greenbrook TMS (Mission Valley) clinical team.
First treatment session — supervised Spravato (intranasal esketamine) in a private treatment room, lasting approximately 90 minutes (40-minute session + 60 minutes monitoring). Sessions are held at 1450 Frazee Road, Suite 210, San Diego, CA 92108. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your Spravato session.
What to Ask on Your Greenbrook TMS (Mission Valley) Consult Call
How long has the Greenbrook TMS (Mission Valley) clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
How long does Greenbrook TMS (Mission Valley)’s Spravato prior authorization typically take with my specific insurance plan, and what happens if it’s denied?
California’s psychedelic-therapy regulatory landscape is evolving — do you stay current with state Department of Public Health and Medical Board guidance on ketamine prescribing?
What does Greenbrook TMS (Mission Valley) recommend for patients who don’t respond to the standard 6-session acute series?
Patient Questions about Greenbrook TMS (Mission Valley)
This 2-question summary is matched to the protocols and conditions Greenbrook TMS (Mission Valley) treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Does Greenbrook TMS (Mission Valley) offer Spravato (esketamine)?
Yes — Greenbrook TMS (Mission Valley) offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.
Is Greenbrook TMS (Mission Valley) suited for treatment-resistant depression?
Greenbrook TMS (Mission Valley) treats depression via Spravato (FDA-cleared for TRD). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
TMS therapy is also available at this clinic, alongside ketamine and Spravato. Unlike cash-pay ketamine, TMS is covered by most major insurance plans for treatment-resistant depression. TMS is FDA-cleared for treatment-resistant depression (since 2008), OCD via Deep TMS, anxious depression, and adolescent MDD ages 15–21. This clinic uses BrainsWay Deep TMS, the only TMS device with standalone FDA clearance for OCD via the H7 coil. Read our complete guide to TMS therapy for FDA-cleared conditions, device differences, insurance coverage by carrier, and what to expect at your first appointment. Browse verified TMS clinics in our directory.
The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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