✓ Last verified: April 17, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: HydraFuse is a health and wellness clinic offering ketamine infusion therapy alongside IV therapy, vitamin drips, and aesthetic services. Their Annapolis location features a multidisciplinary team including a board-certified family nurse practitioner with over a decade of experience and medical staff with expertise in psychology and addiction medicine. They aim to make ketamine therapy more affordable with competitive pricing and waived consultation fees.
| Google Reviews | ⭐ 5.0 on Yelp |
| Location | Annapolis, Maryland |
| Address | 49 Old Solomons Island Rd, Suite 104, Annapolis, MD 21401 |
| Phone | (443) 699-3265 |
| Website | hydrafuserx.com |
| Treatments | Ketamine Infusions, IV Therapy, Vitamin Drips, Aesthetics |
| Conditions Treated | Depression, Anxiety, PTSD, Migraines, Chronic Pain |
| Cost | Competitive pricing; free consultation |
| Insurance | Contact clinic for details |
| KAP Available | Not specified |
| Clinical Lead | Board-certified NP-led multidisciplinary team |
HealingMaps Take: HydraFuse’s Annapolis location stands out for its commitment to affordability—pricing on the lower end of the ketamine therapy spectrum with waived consultation fees. Their perfect 5-star Yelp rating and spa-like wellness environment make for a comfortable treatment experience. The multidisciplinary team with psychology and addiction medicine expertise adds clinical depth beyond a typical infusion-only clinic.
Market Position: HydraFuse treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.
Industry pricing reference. HydraFuse has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine Infusion | $350–$650/session | ✓ |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with integrated talk therapy) | $400–$1,200/session | — |
| At-home oral troches | $150–$300/month | — |
This 2-question summary is matched to the protocols and conditions HydraFuse treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Yes — HydraFuse treats chronic pain. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — HydraFuse treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
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