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✓ Last verified: April 17, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Hydrafuse Annapolis in Annapolis, Maryland logo

Known For: HydraFuse is a health and wellness clinic offering ketamine infusion therapy alongside IV therapy, vitamin drips, and aesthetic services. Their Annapolis location features a multidisciplinary team including a board-certified family nurse practitioner with over a decade of experience and medical staff with expertise in psychology and addiction medicine. They aim to make ketamine therapy more affordable with competitive pricing and waived consultation fees.

Google Reviews⭐ 5.0 on Yelp
LocationAnnapolis, Maryland
Address49 Old Solomons Island Rd, Suite 104, Annapolis, MD 21401
Phone(443) 699-3265
Websitehydrafuserx.com
TreatmentsKetamine Infusions, IV Therapy, Vitamin Drips, Aesthetics
Conditions TreatedDepression, Anxiety, PTSD, Migraines, Chronic Pain
CostCompetitive pricing; free consultation
InsuranceContact clinic for details
KAP AvailableNot specified
Clinical LeadBoard-certified NP-led multidisciplinary team

HealingMaps Take: HydraFuse’s Annapolis location stands out for its commitment to affordability—pricing on the lower end of the ketamine therapy spectrum with waived consultation fees. Their perfect 5-star Yelp rating and spa-like wellness environment make for a comfortable treatment experience. The multidisciplinary team with psychology and addiction medicine expertise adds clinical depth beyond a typical infusion-only clinic.

Market Position: HydraFuse treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.

Is HydraFuse Right for You?

✓ Choose HydraFuse if:

  • You’re treating co-occurring depression and PTSD

✗ Look elsewhere if:

  • You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy

HydraFuse Ketamine Cost Calculator

How Much Will Ketamine Therapy Cost?

Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$460–$788
Range: $394–$1,314/session
Estimated total program
$2,759–$4,730
Range: $2,365–$7,883/6-session series
Your estimate vs. national patient-reported median Based on national tracking, adjusted for Baltimore, MD market
Select a treatment type to see pricing context.

Ketamine Protocols Compared — What’s Offered at HydraFuse

Industry pricing reference. HydraFuse has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

ProtocolTypical Industry CostOffered Here
IV Ketamine Infusion$350–$650/session
Spravato (esketamine)$0–$250 copay (insured)
IM Ketamine$250–$400/injection
KAP (with integrated talk therapy)$400–$1,200/session
At-home oral troches$150–$300/month

What to Expect at Your First HydraFuse Appointment

  1. Initial intake call — Medical history review and clinical eligibility check. Call (443) 699-3265 to schedule. HydraFuse’s posted pricing: Competitive pricing; free consultation.
  2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the HydraFuse clinical team.
  3. First treatment session — supervised ketamine therapy session in a private treatment room, lasting approximately 60–90 minutes. Sessions are held at 49 Old Solomons Island Rd, Suite 104, Annapolis, MD 21401. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
  4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your ketamine session.

What to Ask on Your HydraFuse Consult Call

  • How long has the HydraFuse clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
  • What’s a typical 6-session total cost at HydraFuse, and do you offer payment plans, HSA/FSA-eligible billing, or sliding-scale pricing?
  • Have you obtained Spravato authorization through CareFirst BCBS, Aetna, or Kaiser Permanente Mid-Atlantic — and what’s the typical timeline?
  • What does HydraFuse recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about HydraFuse

This 2-question summary is matched to the protocols and conditions HydraFuse treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Does HydraFuse treat chronic pain conditions?

Yes — HydraFuse treats chronic pain. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does HydraFuse treat PTSD?

Yes — HydraFuse treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

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Healing Maps Editorial Staff

Healing Maps Editorial Staff

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The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

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