✓ Last verified: March 15, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: South Orange County’s premier ketamine and Spravato provider, operating for over a decade from its oceanside Laguna Beach location on Pacific Coast Highway. Known for physician-present ketamine administration and a decade-plus track record.
| Review Scores | 4.8 stars, 15+ Yelp reviews; patients praise professionalism and comfortable environment |
| Location | Laguna Beach, CA |
| Address | 31852 Coast Hwy, Suite 400, Laguna Beach, CA 92651 |
| Phone | (949) 392-0159 |
| Website | ketamineoc.com |
| Treatments | IV Ketamine Infusion, Spravato (Esketamine) |
| Conditions Treated | Treatment-Resistant Depression, Anxiety, PTSD, Trauma, Chronic Pain |
| Cost | Contact for pricing |
| Insurance | Spravato may be covered by insurance; IV ketamine self-pay |
| Clinical Lead | Board-certified anesthesiologists on staff |
💡 No clinic-specific pricing posted? See our ketamine therapy cost guide for typical pricing ranges by treatment type and insurance pathways.
HealingMaps Take: Ketamine Wellness Clinic of Orange County has been operating for over a decade — making it one of the longest-running ketamine practices in Southern California. That longevity matters in a field where many clinics open and close within a few years. The Laguna Beach location on Coast Highway serves South Orange County residents who would otherwise need to drive 30-45 minutes north to Newport Beach or Costa Mesa for ketamine treatment. The clinic maintains a physician-present policy during all ketamine infusions, which is the gold standard for safety but not universal in the industry. The dual offering of IV ketamine and Spravato gives patients flexibility — Spravato’s FDA approval means potential insurance coverage, which can make treatment accessible for patients who cannot afford out-of-pocket infusions. With board-certified anesthesiologists on staff, the medical oversight is strong.
Market Position: Ketamine Wellness Clinic of Orange County is a Spravato-certified clinic in the Beach metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.
Industry pricing reference. Ketamine Wellness Clinic of Orange County has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
This 6-question summary is matched to the protocols and conditions Ketamine Wellness Clinic of Orange County treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Ketamine Wellness Clinic of Orange County offers Spravato and IV ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.
Yes — Ketamine Wellness Clinic of Orange County offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.
Ketamine Wellness Clinic of Orange County treats depression via Spravato (FDA-approved for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Ketamine Wellness Clinic of Orange County treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — Ketamine Wellness Clinic of Orange County treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Yes — Ketamine Wellness Clinic of Orange County treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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