✓ Last verified: March 17, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Boutique medical spa led by Dr. Steven Motarjeme with 25+ years in medicine, offering personalized ketamine infusion therapy on Lake Shore Drive
| Google Reviews | Positively reviewed |
| Location | Chicago, Illinois (Streeterville) |
| Address | 680 N Lake Shore Dr, Suite 1430, Chicago, IL 60611 |
| Phone | (312) 820-8921 |
| Website | medmancave.com |
| Treatments | Ketamine Infusion Therapy |
| Conditions | Depression, Anxiety, Mood Disorders |
| Cost | Competitively priced — contact clinic |
| Insurance | Contact clinic |
| KAP Available | Contact clinic |
| Clinical Lead | Dr. Steven Motarjeme (“Dr. M”), Loyola Stritch School of Medicine |
HealingMaps Take: Medical Man Cave Chicago offers a personalized, boutique ketamine experience under Dr. Steven Motarjeme, a Loyola Stritch School of Medicine graduate with over 25 years in medicine. Reviews consistently praise the individualized attention and comfortable atmosphere. Their Lake Shore Drive location provides a premium setting, and Saturday morning hours add flexibility for working professionals. Part of a multi-city practice also operating in Austin, Denver, and San Diego.
Market Position: Medical Man Cave is a verified ketamine provider in the Chicago metro on HealingMaps — one of 1,473 clinics we have mapped and tracked across 3,142 U.S. counties.
Industry pricing reference. Medical Man Cave has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine Infusion | $350–$650/session | ✓ |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with integrated talk therapy) | $400–$1,200/session | — |
| At-home oral troches | $150–$300/month | — |
This 4-question summary covers the most common patient questions for ketamine clinics in Chicago, Illinois. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Medical Man Cave offers verified ketamine therapy services in Chicago. Specific protocols can include IV ketamine infusion, IM ketamine injection, oral troches, ketamine-assisted psychotherapy (KAP), or Spravato (FDA-approved esketamine) — verify the specific protocol mix with the clinic during your consult call. Multi-protocol practices typically offer more flexibility for matching the modality to your diagnosis and insurance coverage.
Treatment-resistant depression (TRD) — typically defined as failure on two or more antidepressant trials — is the most common qualifier for ketamine therapy and the FDA-approved indication for Spravato. Patients meeting that bar are typical candidates at ketamine clinics like Medical Man Cave. If insurance coverage matters, ask whether they offer Spravato (insurance-covered for TRD) versus IV ketamine (typically self-pay).
Most ketamine clinics treat PTSD and anxiety alongside depression — these three conditions account for ~46% of HealingMaps patient inquiries. Some clinics also treat chronic pain (CRPS, fibromyalgia, neuropathic pain), though pain protocols differ from mental-health protocols (longer infusion times, higher doses). Ask Medical Man Cave which specific conditions they treat most often and how their protocols differ by indication.
Compare ketamine clinics in Chicago, Illinois on three axes: (1) protocol mix — multi-protocol clinics offer flexibility; (2) clinical lead — psychiatrist-led clinics typically include KAP integration, anesthesiologist-led clinics typically focus on infusion; (3) insurance posture — Spravato-certified providers can run insurance coverage; cash-only IV clinics cannot. Medical Man Cave’s positioning on these axes determines whether it’s the right fit for your specific diagnosis and budget.
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