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✓ Last verified: January 27, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Mindful Health Solutions Union Square in San Francisco, California logo

Known For: Centrally located Union Square clinic offering insurance-covered Spravato and cutting-edge MindfulONE single-day TMS from a national depression care leader

Google Reviews4.5 ★
LocationSan Francisco, CA (Union Square)
AddressSan Francisco (Union Square area)
PhoneContact via website
Websitemindfulhealthsolutions.com
TreatmentsSpravato (Esketamine), TMS, MindfulONE TMS, Psychiatric Care
ConditionsTreatment-Resistant Depression, Anxiety, Mood Disorders
CostSpravato & TMS typically covered by insurance
InsuranceMost major insurance accepted
KAP AvailableNo (medically supervised Spravato)
Clinical LeadMindful Health Solutions Psychiatry Team

HealingMaps Take: This Union Square location of Mindful Health Solutions offers the same high-caliber, insurance-covered Spravato treatment as their UCSF clinic, with the added convenience of a central downtown San Francisco location. As the second-largest Spravato administrator nationally, MHS brings significant clinical experience to each treatment. Ideal for patients who want proven, FDA-approved esketamine treatment with insurance coverage in a professional psychiatric setting.

Market Position: Mindful Health Solutions (Union Square) is a Spravato-certified clinic in the Francisco metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.

Is Mindful Health Solutions (Union Square) Right for You?

✓ Choose Mindful Health Solutions (Union Square) if:

  • You have commercial insurance and a documented treatment-resistant depression diagnosis (Spravato pathway)

✗ Look elsewhere if:

  • You’re seeking cash-pay IV ketamine instead of insurance-billed Spravato
  • You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy
  • You need same-week appointments — Spravato prior authorization typically takes 1–3 weeks

⚠ FDA-cleared indications for TMS therapy: treatment-resistant major depressive disorder (MDD), obsessive-compulsive disorder (OCD, Deep TMS only), anxious depression, short-term smoking cessation, and adolescent MDD (ages 15–21). Use of TMS for other conditions including PTSD, bipolar depression, fibromyalgia, and other indications is off-label — not currently FDA-cleared for those specific indications. Discuss your condition with the clinic to understand insurance coverage and clinical evidence.

Mindful Health Solutions (Union Square) Ketamine Cost Calculator

How Much Will Ketamine Therapy Cost?

Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$525–$900
Range: $450–$1,500/session
Estimated total program
$3,150–$5,400
Range: $2,700–$9,000/6-session series
Your estimate vs. national patient-reported median Based on national tracking, adjusted for San Francisco, CA market
Select a treatment type to see pricing context.

Ketamine Protocols Compared — What’s Offered at Mindful Health Solutions (Union Square)

Industry pricing reference. Mindful Health Solutions (Union Square)’s posted price: Spravato & TMS typically covered by insurance. Contact the clinic for any package or sliding-scale options. The calculator above shows metro-level cost estimates across protocols.

ProtocolTypical Industry CostOffered Here
IV Ketamine$350–$650/session
Spravato (esketamine)$0–$250 copay (insured)✓ Yes
IM Ketamine$250–$400/injection
KAP (with therapist)$400–$1,200/session
At-home troches$150–$300/month

What to Expect at Your First Mindful Health Solutions (Union Square) Appointment

  1. Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Schedule via mindfulhealthsolutions.com. Mindful Health Solutions (Union Square)’s posted pricing: Spravato & TMS typically covered by insurance.
  2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Mindful Health Solutions (Union Square) clinical team.
  3. First treatment session — supervised Spravato (intranasal esketamine) in a private treatment room, lasting approximately 90 minutes (40-minute session + 60 minutes monitoring). Sessions are held at San Francisco (Union Square area). You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
  4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your Spravato session.

What to Ask on Your Mindful Health Solutions (Union Square) Consult Call

  • How long has the Mindful Health Solutions (Union Square) clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
  • How long does Mindful Health Solutions (Union Square)’s Spravato prior authorization typically take with my specific insurance plan, and what happens if it’s denied?
  • California’s psychedelic-therapy regulatory landscape is evolving — do you stay current with state Department of Public Health and Medical Board guidance on ketamine prescribing?
  • What does Mindful Health Solutions (Union Square) recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about Mindful Health Solutions (Union Square)

This 3-question summary is matched to the protocols and conditions Mindful Health Solutions (Union Square) treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Does Mindful Health Solutions (Union Square) offer Spravato (esketamine)?

Yes — Mindful Health Solutions (Union Square) offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.

Is Mindful Health Solutions (Union Square) suited for treatment-resistant depression?

Mindful Health Solutions (Union Square) treats depression via Spravato (FDA-approved for TRD). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Can Mindful Health Solutions (Union Square) help with anxiety disorders?

Yes — Mindful Health Solutions (Union Square) treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

This clinic offers TMS therapy as a third FDA-cleared treatment option (alongside ketamine and Spravato) for patients with treatment-resistant depression. Patients drive themselves to and from sessions, return to work the same day, and need no chaperone or recovery period. This clinic uses BrainsWay Deep TMS, the only TMS device with standalone FDA clearance for OCD via the H7 coil. Read our complete guide to TMS therapy for FDA-cleared conditions, device differences, insurance coverage by carrier, and what to expect at your first appointment. Browse verified TMS clinics in our directory.

View all REMS-certified Spravato clinics in California and across the United States.

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Healing Maps Editorial Staff

Healing Maps Editorial Staff

View all posts by Healing Maps Editorial Staff

The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

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