Tidewater Health & Ketamine Center – Mount Pleasant, South Carolina Ketamine Clinics

1435 Stuart Engals Blvd, Suite 101, Mount Pleasant, SC 29464

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✓ Last verified: February 2, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Charleston’s only ketamine clinic that also specializes in opioid addiction treatment — offering IV ketamine infusions alongside Medication-Assisted Treatment (MAT) and Suboxone for a patient population where depression and substance use often coexist.

Review Scores	Positive reviews; patients praise the dual focus on mood disorders and addiction treatment
Location	Mount Pleasant, SC
Address	1435 Stuart Engals Blvd, Suite 101, Mount Pleasant, SC 29464
Phone	(843) 800-5686
Website	tidewaterhealth.org
Treatments	IV Ketamine Infusion, Medication-Assisted Treatment (MAT) for Opioid Use Disorder, Suboxone
Conditions Treated	Treatment-Resistant Depression, Anxiety, PTSD, Chronic Pain, Opioid Use Disorder
Cost	Contact for pricing
Insurance	Contact for insurance details
Clinical Lead	Medical team specializing in ketamine infusion and addiction medicine

💡 No clinic-specific pricing posted? See our ketamine therapy cost guide for typical pricing ranges by treatment type and insurance pathways.

HealingMaps Take: Tidewater Health & Ketamine Center occupies a unique niche in the Charleston market by combining ketamine infusion therapy with addiction medicine. This dual focus is clinically significant: treatment-resistant depression and opioid use disorder frequently co-occur, and patients struggling with both conditions have historically fallen through the cracks — ketamine clinics would not treat active substance use, and addiction clinics did not offer ketamine. Tidewater bridges that gap. The Stuart Engals Boulevard location in Mount Pleasant provides a medical office setting that is accessible from both sides of the Cooper River. The Suboxone/MAT program means patients can receive their opioid addiction treatment and their depression treatment at the same practice, reducing the logistical burden that causes so many dual-diagnosis patients to drop out of care. For patients in the Charleston metro who are dealing with treatment-resistant depression alongside opioid use disorder — or for those whose chronic pain led them down both the depression and the opioid path — Tidewater offers an integrated model that understands the intersection.

Market Position: Tidewater Health & Ketamine Center is an IV-ketamine-focused clinic in the Pleasant metro — the most common cash-pay protocol in the HealingMaps verified directory.

Is Tidewater Health & Ketamine Center Right for You?

✓ Choose Tidewater Health & Ketamine Center if:

You want supervised IV ketamine with real-time medical monitoring
You’re treating co-occurring depression and PTSD

✗ Look elsewhere if:

You need Spravato (FDA-approved esketamine) covered by your insurance
You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy

Tidewater Health & Ketamine Center Ketamine Cost Calculator

How Much Will Ketamine Therapy Cost?

Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.

Treatment type

Sessions planned

Insurance

Estimated per session

$525–$900

Range: $450–$1,500/session

Estimated total program

$3,150–$5,400

Range: $2,700–$9,000/6-session series

Your estimate vs. national patient-reported median Based on national tracking, adjusted for Manhattan, NY market

Select a treatment type to see pricing context.

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Ketamine Protocols Compared — What’s Offered at Tidewater Health & Ketamine Center

Industry pricing reference. Tidewater Health & Ketamine Center has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

Protocol	Typical Industry Cost	Offered Here
IV Ketamine	$350–$650/session	✓ Yes
Spravato (esketamine)	$0–$250 copay (insured)	—
IM Ketamine	$250–$400/injection	—
KAP (with therapist)	$400–$1,200/session	—
At-home troches	$150–$300/month	—

What to Expect at Your First Tidewater Health & Ketamine Center Appointment

Initial intake call — Brief medical history review, depression and anxiety screening, and medical clearance for IV ketamine. Call (843) 800-5686 to schedule.
Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Tidewater Health & Ketamine Center clinical team.
First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 1435 Stuart Engals Blvd, Suite 101, Mount Pleasant, SC 29464. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your Tidewater Health & Ketamine Center Consult Call

How long has the Tidewater Health & Ketamine Center clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
Does Tidewater Health & Ketamine Center provide a superbill for out-of-network insurance reimbursement, and what’s a typical 6-session total cost including any follow-up?
What does Tidewater Health & Ketamine Center recommend for patients who don’t respond to the standard 6-session acute series?

Pleasant Ketamine Market Snapshot

Sources: CDC PLACES 2023 (Charleston County, SC, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.

Adult depression in Charleston County, SC: 21.8%
Frequent mental distress (14+ days per month): 15.1%
Adults lacking health insurance: 9.5%
Charleston County population: 409,840 · median household income $78,795
Recent Pleasant-area inquiries to HealingMaps: A growing stream of South Carolina residents have recently contacted us seeking ketamine care

Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.

13.5% of ketamine inquiries specifically cite PTSD — second only to depression as a driver of patient demand in the HealingMaps corpus. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.

Patient Questions about Tidewater Health & Ketamine Center

This 4-question summary is matched to the protocols and conditions Tidewater Health & Ketamine Center treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Is Tidewater Health & Ketamine Center suited for treatment-resistant depression?

Tidewater Health & Ketamine Center treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Tidewater Health & Ketamine Center treat chronic pain conditions?

Yes — Tidewater Health & Ketamine Center treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does Tidewater Health & Ketamine Center treat PTSD?

Yes — Tidewater Health & Ketamine Center treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Tidewater Health & Ketamine Center help with anxiety disorders?

Yes — Tidewater Health & Ketamine Center treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

Learn more about the evidence behind ketamine for depression at the National Institute of Mental Health.

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Healing Maps Editorial Staff

View all posts by Healing Maps Editorial Staff

The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

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Tidewater Health & Ketamine Center – Mount Pleasant, South Carolina Ketamine Clinics