Bespoke Treatment – IOP, Ketamine & TMS Therapy – Los Angeles, California Ketamine Clinics, Spravato Clinics, TMS Therapy Clinics

✓ Last verified: April 17, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Comprehensive mental health center combining ketamine therapy, TMS, Spravato, and intensive outpatient programming (IOP) with insurance acceptance. Multiple LA-area locations including Santa Monica and Las Vegas.

HealingMaps Take: Bespoke Treatment is one of the most comprehensive mental health practices in LA, offering ketamine therapy within a full continuum of care that includes TMS, Spravato, IOP/PHP programming, and traditional psychiatry. Their insurance acceptance for many services makes them one of the more accessible options in the LA market. The Downtown location is convenient for central LA, and additional locations expand reach across the Westside. With a 4.8-star Google rating and a multi-modal approach, Bespoke is ideal for patients who need more than just ketamine — they can step up or down between treatment levels as needed.

Market Position: Bespoke Treatment is a Spravato-certified clinic in the Angeles metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.

Bespoke Treatment Ketamine Cost Calculator

Ketamine Protocols Compared — What’s Offered at Bespoke Treatment

Industry pricing reference. Bespoke Treatment has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

What to Expect at Your First Bespoke Treatment Appointment

1. Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Call 833-248-7221 to schedule.
2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Bespoke Treatment clinical team.
3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 250 1st St, Suite 300, Los Angeles, CA 90012. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your Bespoke Treatment Consult Call

• How long has the Bespoke Treatment clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
• Walk me through Bespoke Treatment’s Spravato prior authorization process versus your IV ketamine cash-pay or superbill workflow — which is the better fit for my insurance situation?
• California’s psychedelic-therapy regulatory landscape is evolving — do you stay current with state Department of Public Health and Medical Board guidance on ketamine prescribing?
• What does Bespoke Treatment recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about Bespoke Treatment

This 5-question summary is matched to the protocols and conditions Bespoke Treatment treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

What ketamine protocols does Bespoke Treatment offer?

Bespoke Treatment offers Spravato and IV ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.

Does Bespoke Treatment offer Spravato (esketamine)?

Yes — Bespoke Treatment offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.

Is Bespoke Treatment suited for treatment-resistant depression?

Bespoke Treatment treats depression via Spravato (FDA-approved for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Bespoke Treatment treat PTSD?

Yes — Bespoke Treatment treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Bespoke Treatment help with anxiety disorders?

Yes — Bespoke Treatment treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

View all REMS-certified Spravato clinics in California and across the United States.

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