Tri-MED – Sherman, Texas Ketamine Clinics

✓ Last verified: February 22, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Tri-MED’s Sherman location extends their ketamine infusion therapy to the Texoma region near the Oklahoma border. Part of the Tri-MED network with a Frisco office, this location serves Sherman, Denison, and surrounding communities with IV ketamine for depression, anxiety, PTSD, and chronic pain.

HealingMaps Take: Tri-MED’s Sherman location is essential for the Texoma region, where ketamine providers are nonexistent without driving to DFW. Serves both Texas and southern Oklahoma patients near the border.

Market Position: Tri-MED is an IV-ketamine-focused clinic in the Sherman metro — the most common cash-pay protocol in the HealingMaps verified directory.

Tri-MED Ketamine Cost Calculator

Ketamine Protocols Compared — What’s Offered at Tri

Industry pricing reference. Tri has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

What to Expect at Your First Tri Appointment

1. Initial intake call — Brief medical history review, depression and anxiety screening, and medical clearance for IV ketamine. Call (903) 221-8020 to schedule.
2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Tri clinical team.
3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 1601 North Travis Street, Sherman, TX 75092. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your Tri Consult Call

• How long has the Tri clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
• Does Tri provide a superbill for out-of-network insurance reimbursement, and what’s a typical 6-session total cost including any follow-up?
• Texas has limited insurance coverage for IV ketamine — what’s the typical out-of-pocket cost trajectory for cash-pay patients in your practice?
• What does Tri recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about Tri-MED

This 4-question summary is matched to the protocols and conditions Tri-MED treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Is Tri-MED suited for treatment-resistant depression?

Tri-MED treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Tri-MED treat chronic pain conditions?

Yes — Tri-MED treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does Tri-MED treat PTSD?

Yes — Tri-MED treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Tri-MED help with anxiety disorders?

Yes — Tri-MED treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

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