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HealingMaps Take: Pearl District longevity and peptide clinic led by Chris Kleronomos, FNP-BC (functional/integrative and anti-aging medicine), with an unusually deep named peptide menu — BPC-157, TB-500, CJC-1295/Ipamorelin, GHRP-6, Sermorelin, Tesamorelin, GHK-Cu, KPV, Epitalon, Semax, Selank — plus recovery, anti-aging, and cognitive blends.. Chris Kleronomos leads the clinical team and protocols are tailored to each patient’s goals after consultation.
Upgrade PDX offers 11 specific peptide compounds (BPC-157, TB-500, CJC-1295, Ipamorelin, Sermorelin, Tesamorelin, and 5 more), placing it the deepest disclosed menu of any of the 10+ Oregon peptide clinics in our directory. The named clinical lead is a Nurse Practitioner or Physician Assistant rather than an MD/DO.
✓ Edited by Angelica Bottaro for HealingMaps Editorial Staff
| Location | Portland, Oregon |
| Address | 1210 NW Johnson St, Portland, OR 97209 |
| Phone | (971) 299-8350 |
| Website | upgradepdx.com |
| Treatments | BPC-157, TB-500, CJC-1295, Ipamorelin, GHRP-6, Sermorelin, Tesamorelin, GHK-Cu, KPV, MGF, Epitalon, Semax, Selank |
| Conditions Treated | Recovery, injury & tendon repair, anti-aging/longevity, growth-hormone optimization, cognitive support, performance |
| Administration | Subcutaneous injection |
| Cost | N/A |
| Insurance | N/A |
| Clinical Lead | Chris Kleronomos, FNP-BC — Family Nurse Practitioner & Medical Director (DAOM, A4M) |
Who Will Prescribe Your Peptides?
Your prescribing provider, Chris Kleronomos, FNP-BC, is verified in the federal CMS National Plan & Provider Enumeration System (NPPES) under NPI 1144540436, with a primary specialty of Nurse Practitioner, Family and a primary practice address in Portland, OR. CMS records show this NPI has been active since 2010. NPPES record verified 2026-06-29.
What this means for you: In the US, any actively state-licensed physician can legally prescribe compounded peptides — board certification in a specific specialty isn’t required for peptide prescriptions.
💊 Try Peptide Therapy Online
Embody connects you with licensed providers for personalized peptide protocols — no in-person visit required. GLP-1, BPC-157, Sermorelin, and more.
Get Started with Embody →Typical Peptide Therapy Cost in the U.S.
National peptide therapy pricing — based on 487 verified peptide clinics in our directory (April 2026 data). Adjust the calculator below to model your own protocol.
How Much Will Peptide Therapy Cost?
Estimate your monthly and program cost based on HealingMaps proprietary clinic pricing data across 487 verified peptide clinics.
Ongoing monthly
$200–$500
Range: $99–$600/mo
First month (incl. consult + labs)
$550
Range: $449–$950
Estimated program total
$1,550
Range: $944–$3,950
First-month setup varies. Some clinics bundle it; others bill consult + labs separately. Ask this clinic for exact pricing.
Select a peptide program to see pricing context.
Is Upgrade PDX the right fit for you?
✓ Choose Upgrade PDX if:
- You’re in or willing to travel to Portland — peptide therapy generally requires in-person consultation and ongoing follow-ups.
- You want a broad compound menu — this listing names 11 specific peptides, among the deepest in the market.
- You want one of the most comprehensive peptide menus in the metro — this listing ranks #1 out of 13 we’ve reviewed locally.
✗ Look elsewhere if:
- You need to start treatment within the same week. Most peptide programs require baseline labs (1-3 days) plus pharmacy fulfillment (a few more days) before your first dose — plan on 1-3 weeks from consult call to first injection.
- You’re shopping primarily on price and need per-compound rates published up front. Most clinics share specific pricing only on the consult call. Use our cost calculator above for ballpark estimates and confirm specifics with the clinic.
- You specifically want a physician-led practice — the named clinical lead here is a Nurse Practitioner or Physician Assistant.
- You want a clinic that publicly states its 503A or 503B compounding pharmacy — this listing doesn’t disclose sourcing.
What to Expect at Your First Upgrade PDX Appointment
- Initial consultation / intake — typically 30–60 minutes reviewing medical history, goals, current medications, and prior labs.
- Baseline lab work — most clinics require labs before prescribing growth-hormone secretagogues (CJC-1295/Ipamorelin, Sermorelin) and GLP-1s (semaglutide, tirzepatide), since those compounds modulate endocrine and metabolic pathways. Tissue-repair peptides (BPC-157, TB-500), sexual-wellness peptides (PT-141), and topical compounds are sometimes prescribed without labs. This listing doesn’t explicitly state lab requirements, so confirm on your consult call which panels they require for your specific protocol. Even when labs aren’t strictly required, they’re a smart personal baseline. See our guide to peptide therapy lab work for what to ask about.
- Protocol design — this listing publishes a deep menu (11 compounds, including BPC-157, TB-500, CJC-1295, Ipamorelin, and others). Your provider narrows the protocol based on your goals, labs, and any contraindications.
- Prescription written + sent to compounding pharmacy — The clinic doesn’t publicly state its 503A or 503B sourcing, so confirm fulfillment timing on your consult call (in-state-only vs. nationwide; compounded-after-Rx vs. pre-batched).
- Self-administration training — for injectable peptides, the clinic walks you through subcutaneous injection technique, needle handling, refrigeration, and rotation sites.
- Follow-up — typically a 4–6 week check-in to assess response, side effects, and whether dose or compound needs adjustment.
Most Upgrade PDX patients report the consult-to-first-injection window runs 1–3 weeks depending on lab turnaround and pharmacy fulfillment.
What to Ask on Your Upgrade PDX Consult Call
The questions below are pulled from the gaps in this specific listing — areas the clinic doesn’t publicly answer that you should clarify before booking. Each one is designed to get you a useful answer in 30 seconds or less.
- “Of these 11 compounds, which do most patients with my goals end up on?” A deep menu can mean either deep expertise or unfocused offerings — ask which compounds the clinic actually has the most experience with.
- “Is your compounding pharmacy 503A or 503B, and which specific pharmacy do you use?” The class affects whether your prescription is custom-compounded (503A) or pre-batched (503B), and whether they can ship across state lines.
- “Who is the supervising physician for the named NP/PA, and how often do they review my protocol?” NPs and PAs prescribe under collaborative agreements with state-specific scope-of-practice rules — know who’s behind the prescription.
- “Which lab panels do you require for the protocol you’d recommend for me?” Clinics typically require baseline labs for hormone-modulating compounds (semaglutide, tirzepatide, growth-hormone secretagogues) and may skip them for some tissue-repair or topical compounds. Knowing your clinic’s specific lab requirements helps you compare to peers — and even when not required, baseline labs are smart personal protection.
- “What’s the total first-month cost — consult fee, labs, and initial prescription combined?” First-month all-in is usually 1.5–2× the recurring monthly cost. Ask for an itemized breakdown.
- “Is follow-up telehealth-friendly, or are in-person visits required at every milestone?” The listing doesn’t mention telehealth — important to know if you travel or move.
- “From my consult to my first injection, how long is the typical timeline?” Lab turnaround + pharmacy fulfillment usually means 1–3 weeks. Confirms expectations.
About Upgrade PDX
Upgrade PDX operates in Portland, Oregon and offers peptide therapy. The clinic’s peptide menu includes bpc-157, tb-500, cjc-1295 and related compounds, administered via subcutaneous injection.
For a closer look at how these compounds work, read our deep dives on the CJC-1295 and Ipamorelin growth-hormone peptide stack and BPC-157, the body protection compound for tissue recovery.
What People Like
Clinician-led (FNP-BC, functional-medicine credentialed); unusually deep, published peptide menu; recovery + longevity + cognitive focus; Pearl District location
What People Don’t Like
Compounded peptides are cash-pay; broad longevity menu alongside the peptide program
Getting Started at Upgrade PDX
Call (971) 299-8350 or visit upgradepdx.com to schedule a peptide consultation with Chris Kleronomos, FNP-BC in Portland.
Explore more our guide to the best peptide clinics in Portland.
Frequently Asked Questions
What peptides does Upgrade PDX offer?
Based on this listing, Upgrade PDX names 11 specific peptide compounds: BPC-157, TB-500, CJC-1295, Ipamorelin, Sermorelin, Tesamorelin, and 5 more. The clinic may offer additional compounds not published on its public listing — confirm the full menu on a consult call.
Is the clinical lead at Upgrade PDX a verified physician?
Yes. Chris Kleronomos, FNP-BC is registered in the federal CMS National Plan & Provider Enumeration System (NPPES) under NPI 1144540436, with a primary specialty of Nurse Practitioner, Family and a primary practice address in Portland, OR. The NPI has been active since 2010.
Does Upgrade PDX offer telehealth or virtual visits?
Upgrade PDX doesn’t mention telehealth or virtual visits on its listing. Most peptide clinics require in-person evaluation for the initial consult; some offer virtual follow-ups once a patient is stable. If geography or travel matters to you, ask on the consult call whether they can prescribe and follow up virtually — and which states they’re licensed to do so in.
How does Upgrade PDX compare to other Oregon peptide clinics?
Among verified Oregon peptide clinics in the HealingMaps directory, Upgrade PDX ranks the deepest disclosed peptide menu of any Oregon clinic in the directory. Compound depth is one signal among several — provider credentials, pharmacy sourcing transparency, and lab requirements also matter when comparing.
Where is Upgrade PDX located?
Upgrade PDX is located in Portland, Oregon. The full street address, phone number, and hours are listed in the data card above.
What Oregon Peptide Patients Are Likely Asking
Themes drawn from HealingMaps editorial analysis of verified Oregon peptide clinics in our directory. Refreshed quarterly; percentages rounded to nearest 5%.
Which peptides do most Oregon clinics actually offer?
Across Oregon peptide clinics in our directory, BPC-157 appears in 100% of listings; Sermorelin in 85%; Semaglutide in 55%; Tirzepatide in 55%. Compounds appearing in fewer than 20% of Oregon listings — including Epitalon, KPV, MOTS-c — are less commonly disclosed; patients seeking those should specifically ask whether the clinic prescribes them.
How transparent are Oregon clinics about their compounding pharmacy?
15% of Oregon clinics in our directory openly state whether they use a 503A or 503B compounding pharmacy. The rest leave the class unstated. The distinction matters for patients — 503A pharmacies fill prescriptions individually after your provider writes them (typically a few-day wait, in-state shipping), while 503B outsourcing facilities pre-batch under direct FDA inspection (often supporting same-visit fulfillment and direct-to-home shipping). Worth asking specifically before you book.
Who’s actually prescribing peptides in Oregon?
45% of verified Oregon clinics name an MD or DO as clinical lead (this listing’s clinical lead is Nurse Practitioner, Family-trained). The remainder are NP/PA-led or don’t publicly name a specific prescribing clinician. Any state-licensed physician, NP, or PA can legitimately prescribe compounded peptides — but knowing your prescriber’s training and tenure helps you assess fit for your specific protocol.
How deep are Oregon peptide menus typically?
The median Oregon clinic in our directory publishes 7 specific peptide compounds on its listing. The deepest disclosed menu names 11; every clinic names at least one compound. A wide menu means more options at one clinic; a narrow menu can reflect specialization (e.g. weight-loss-only programs) or limited public disclosure (the clinic prescribes more than it advertises).
Pharmacy sourcing: This clinic doesn’t state its 503A or 503B compounding pharmacy partner. The class affects how your prescription is fulfilled — custom-compounded with in-state shipping (503A) versus pre-batched with broader shipping including direct-to-home delivery (503B) — so it’s worth asking before starting any compounded protocol.
How we vetted this clinic
We confirmed Upgrade PDX’s named prescriber in CMS NPPES records. 11 peptide compounds on the menu — BPC-157, TB-500, and CJC-1295 among them. The clinic doesn’t specify pharmacy class (503A vs 503B) publicly — a reasonable thing to ask about before you book. See our full vetting rubric →
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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