865 Wellness + Ketamine – Knoxville, Tennessee Ketamine Clinics

✓ Last verified: January 22, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Knoxville’s locally-owned ketamine clinic offering both IV ketamine and Spravato under one roof — distinguished by published pricing transparency and a non-corporate, community-oriented practice model.

HealingMaps Take: 865 Wellness + Ketamine occupies an important position in the Knoxville market as a locally-owned alternative to the larger multi-state chains (Revitalist) that dominate Tennessee ketamine treatment. Local ownership matters clinically because it often means consistency in clinicians, more personalized care, and pricing that reflects local market conditions rather than national corporate models. Their offering of both IV ketamine and Spravato means patients don’t need to choose a clinic based on which treatment they want — the clinic meets them wherever they are in their treatment journey. The published pricing transparency (rare in the Knoxville market) signals a practice confident in its clinical value and willing to compete on trust rather than opacity. The South Concord Street location on the west side of Knoxville near Bearden is convenient for patients from Cedar Bluff, Farragut, and the west Knoxville corridor. For Knoxville patients who want a locally-accountable ketamine clinic rather than a national chain, 865 Wellness is the clear choice.

Market Position: 865 Wellness + Ketamine is a Spravato-certified clinic in the Knoxville metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.

Ketamine Protocols Compared — What’s Offered at 865 Wellness + Ketamine

Industry pricing reference. 865 Wellness + Ketamine has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

What to Expect at Your First 865 Wellness + Ketamine Appointment

1. Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Call (865) 805-3118 to schedule.
2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the 865 Wellness + Ketamine clinical team.
3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 601 S Concord Street, Suite 100, Knoxville, TN 37919. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your 865 Wellness + Ketamine Consult Call

• How long has the 865 Wellness + Ketamine clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
• Walk me through 865 Wellness + Ketamine’s Spravato prior authorization process versus your IV ketamine cash-pay or superbill workflow — which is the better fit for my insurance situation?
• How do you handle BCBS Tennessee, Cigna, and Aetna Spravato authorizations — and what’s the typical PA approval timeline?
• What does 865 Wellness + Ketamine recommend for patients who don’t respond to the standard 6-session acute series?

Knoxville Ketamine Market Snapshot

Sources: CDC PLACES 2023 (Knox County, TN, crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.

• Adult depression in Knox County, TN: 30.7%
• Frequent mental distress (14+ days per month): 19.5%
• Adults lacking health insurance: 10.2%
• Knox County population: 481,406 · median household income $68,580
• Recent Knoxville-area inquiries to HealingMaps: A growing stream of Tennessee residents have recently contacted us seeking ketamine care

Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.

From the 2026 Ketamine Industry Report

Telehealth ketamine programs undercut in-clinic pricing by 40–60%, but 64.8% of surveyed patients still prefer supervised in-clinic treatment — a clear cost-vs-safety tradeoff patients should weigh before choosing an at-home program. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.

Patient Questions about 865 Wellness + Ketamine

This 6-question summary is matched to the protocols and conditions 865 Wellness + Ketamine treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

What ketamine protocols does 865 Wellness + Ketamine offer?

865 Wellness + Ketamine offers Spravato and IV ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.

Does 865 Wellness + Ketamine offer Spravato (esketamine)?

Yes — 865 Wellness + Ketamine offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.

Is 865 Wellness + Ketamine suited for treatment-resistant depression?

865 Wellness + Ketamine treats depression via Spravato (FDA-approved for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does 865 Wellness + Ketamine treat chronic pain conditions?

Yes — 865 Wellness + Ketamine treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does 865 Wellness + Ketamine treat PTSD?

Yes — 865 Wellness + Ketamine treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can 865 Wellness + Ketamine help with anxiety disorders?

Yes — 865 Wellness + Ketamine treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

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