✓ Last verified: February 14, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Advanced Pain Relief Institute in San Antonio provides IV ketamine infusion therapy within a specialized pain management practice. With locations across South Texas including Boerne and Beeville, the clinic serves the greater San Antonio metro and surrounding Hill Country communities with personalized ketamine protocols for chronic pain and mood disorders.
Google Reviews
⭐ Multi-location South TX
Location
San Antonio, Texas
Address
4100 E. Piedras Drive, #165, San Antonio, TX 78228
HealingMaps Take: Advanced Pain Relief Institute’s San Antonio location is the hub of their South Texas ketamine network. Their pain management specialization makes them especially well-suited for chronic pain patients, and the memorable domain (mypainsucks.com) reflects their patient-first philosophy. Also see their Boerne and Beeville locations on HealingMaps.
Market Position: Advanced Pain Relief Institute is an IV-ketamine-focused clinic in the Antonio metro — the most common cash-pay protocol in the HealingMaps verified directory.
Is Advanced Pain Relief Institute Right for You?
✓ Choose Advanced Pain Relief Institute if:
You want supervised IV ketamine with real-time medical monitoring
✗ Look elsewhere if:
You need Spravato (FDA-approved esketamine) covered by your insurance
You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy
Advanced Pain Relief Institute Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$471–$807
Range: $403–$1,344/session
Estimated total program
$2,823–$4,840
Range: $2,420–$8,066/6-session series
Your estimate vs. national patient-reported medianBased on national tracking, adjusted for San Antonio, TX market
Select a treatment type to see pricing context.
Get matched to verified clinics
A HealingMaps specialist will follow up within one business day with providers that match your estimate, protocol, and insurance situation.
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A HealingMaps specialist will reach out within one business day with clinic matches based on your estimate. In the meantime, review the verified providers below.
Ketamine Protocols Compared — What’s Offered at Advanced Pain Relief Institute
Industry pricing reference. Advanced Pain Relief Institute has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
Protocol
Typical Industry Cost
Offered Here
IV Ketamine
$350–$650/session
✓ Yes
Spravato (esketamine)
$0–$250 copay (insured)
—
IM Ketamine
$250–$400/injection
—
KAP (with therapist)
$400–$1,200/session
—
At-home troches
$150–$300/month
—
What to Expect at Your First Advanced Pain Relief Institute Appointment
Initial intake call — Brief medical history review, depression and anxiety screening, and medical clearance for IV ketamine. Call (210) 910-6653 to schedule.
Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Advanced Pain Relief Institute clinical team.
First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 4100 E. Piedras Drive, #165, San Antonio, TX 78228. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.
What to Ask on Your Advanced Pain Relief Institute Consult Call
How long has the Advanced Pain Relief Institute clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
Does Advanced Pain Relief Institute provide a superbill for out-of-network insurance reimbursement, and what’s a typical 6-session total cost including any follow-up?
Texas has limited insurance coverage for IV ketamine — what’s the typical out-of-pocket cost trajectory for cash-pay patients in your practice?
What does Advanced Pain Relief Institute recommend for patients who don’t respond to the standard 6-session acute series?
Patient Questions about Advanced Pain Relief Institute
This 2-question summary is matched to the protocols and conditions Advanced Pain Relief Institute treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Is Advanced Pain Relief Institute suited for treatment-resistant depression?
Advanced Pain Relief Institute treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Does Advanced Pain Relief Institute treat chronic pain conditions?
Yes — Advanced Pain Relief Institute treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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Deidre Cuellar
September 8, 2022 at 11:52 pmI’m interested
Helpful Review