FREE Private Self Assessment
Kentukiana Integrative Medicine Logo.

Testimonials from Kentuckiana Integrative Medicine Patients

“Ketamine Therapy saved me after years of depression and not getting help from countless antidepressants. Now I am finally happy and have found a great IT job.”

K. Perkins

Ketamine Therapy is truly a lifesaver. I was suicidal. Marriage in trouble. Now I am pleased with life, marriage and work and just finished nursing medical school.

Sarah F.
FREE Private Self Assessment

Kentuckiana Integrative Medicine, with a main clinic in Jeffersonville, Indiana, provides ketamine infusion therapy to the Indiana and Kentucky regions. Recent research at leading universities shows ketamine to be a powerful medicine. It has changed how people with resistant pain and mental health conditions approach healing and growth. As a result, the staff at the Kentuckiana clinic offers this treatment for those suffering from conditions ranging from depression and bipolar disorder to CRPS and fibromyalgia.

Ketamine infusion therapy has benefits for a wide variety of sufferers. Those seeking this powerful treatment suffer from conditions called “refractory”, or “resistant”. Such conditions have not responded positively to mainstream treatments and therapies. Of those who undergo this treatment, 70-80 percent report significant positive results.

Kentuckiana Ketamine Institute is one the most experienced Ketamine Treatment centers in Kentuckiana and the country. There is no other anti-suicidal and antidepressant therapy that is as fast, accessible and as effective as Ketamine Therapy. Many patients see improvement even after the first treatment. Six treatments within 2-3 weeks are required for best results and occasionally “booster” treatments. Over seven years ago, Kentuckiana introduced Ketamine to the community for mental health challenges such as Treatment Resistant Depression, Postpartum Depression, Reactive Depression, Bipolar Disorder, PTSD, OCD, Severe Anxiety and Pain Issues [Fibromyalgia, Neuropathy, Migraines Multiple Sclerosis] with tremendous success.

A Recognized Leader

Dr. Rafael F. Cruz, M.D. runs Kentuckiana Integrative Medicine. A recognized leader in integrative practices, Dr. Cruz combines cutting-edge research with non-mainstream practices. The resulting combination leads to a personally-tailored treatment plan for every visitor to the clinic. In fact, the holistic practice of Dr. Cruz is reflected in the compassionate and understanding staff at Kentuckiana. Sufferers will find a welcome and comfortable environment in which to heal.

Dr. Cruz has over 25 years of clinical experience in Emergency Medicine, Anesthesia and Integrative Medicine and is extremely experienced in the safe use of Ketamine therapy. Over 30 years ago, he personally experienced the devastating effects of depression so he can relate well to his patients. Kentuckiana Integrative Medicine treats individuals with listed conditions as young as 12 years old, something few clinics are available to do.

Mainstream treatment is successful for a wide range of pain and mental health conditions. With this in mind, for conditions that continue to resist oral medications and physical therapies, ketamine infusion offers a fast and effective avenue. The experts at Kentuckiana Integrative Medicine will guide you with expertise and gentleness into a new lease on life.

You will be treated with the compassion and respect you deserve in a clean private room with a spa like environment including Lazy boy chair with heat, massage, blanket and more. You will learn lifelong techniques and strategies that will dramatically enhance your potential for success. Experience the difference at Kentuckiana Ketamine Institute, where your improvement is the clinic’s most important mission.

Offered Treatments

Kentuckiana Integrative Medicine primarily utilizes IV Intravenous and IM Intramuscular Ketamine therapy. However, Nasal Spravato Ketamine is offered for adults with Medicare or commercial insurance when coverage is available. Nasal Spravato Ketamine is only approved for treatment resistant depression in patients who have tried and failed to improve with at least 2-3 anti-depressants or ECT or TCM therapies.

Kentuckiana Integrative Medicine currently cannot accept Medicaid insurances.

  • IV Ketamine Infusion Therapy
  • Spravato ketamine nasal spray

Ketamine therapy can help patients with a variety of conditions:

  • Neuropathic Pain
    • Trigeminal Neuralgia
    • CRPS (Complex Regional Pain Syndrome)
    • RSD (Reflex Sympathetic Dystrophy)
    • Phantom Limb pain
    • Diabetic pain
    • Post-herpetic Neuralgia
  • Chronic back and neck pain
  • Fibromyalgia
  • Debilitating Musculoskeletal and Joint Pain
  • Migraines
  • PTSD (Post Traumatic Stress Disorder)
  • OCD (Obsessive Compulsive Disorder)
  • Suicidal Thinking
  • Treatment Resistant Depression
  • Bipolar Disorder
  • Reactive Depression
  • Postpartum Depression
  • Addictions
  • Severe Anxiety

Cost of Treatment

  • Consult – $300
  • Treatment – $2,500-$6,000 for seven treatments of Ketamine

The higher costs listed are if other services are desired such as IV Vitamin therapy which is indicated when there is a history of severe fatigue, fibromyalgia, recurrent infections, etc.

Your Treatment: What to Expect

An initial assessment is necessary to rule out potential contraindications. Patients undergo a series of infusions over 1-2 weeks. Although a psychedelic compound, ketamine is infused in small enough amounts that side effects are subtle, and often quite pleasurable. First infusions at Kentuckiana Integrative Medicine are at a lower dose. Upon establishing tolerance to the medication, subsequent infusions are stronger and longer.

FREE Private Self Assessment

Ketamine is an effective medicine for most who come to it. However, approximately 20 percent of patients do not respond positively to the medication. Positive results cannot be guaranteed.

Also read: What is Ketamine Used For: From Mental Health Issues to Chronic Pain

Who is this treatment for?

Ketamine therapy is not the first stop on the road to treating pain and mental health issues. Those who come to Kentuckiana Integrative Medicine will have tried other medications and therapies first. Once a condition is considered to be “resistant”, clinical trials with ketamine infusion show a 70-80 percent success rate. Kentuckiana Integrative Medicine can offer hope, healing, and growth.

More Information


Review (1)

5.0 out of 5.0
Service 5.0
Value for Money 5.0
Location 5.0
Cleanliness 5.0
  • Karen A Sherlock
    August 26, 2022 at 10:00 pm

    Excellent Facility with knowledgeable and compassionate team that are dedicated to helping patients with pain and mental health challenges. Ketamine genuinely save my life bringing back joy and function. I cannot thank you enough.
    Karen Louisville, KY

    Helpful Review

Add Review

Leave a Reply

Your email address will not be published. Required fields are marked *

Value for Money

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

FREE Private Self Assessment
Healing Maps Editorial Staff

Healing Maps Editorial Staff

View all posts by Healing Maps Editorial Staff

The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

Explore Psychedelic Therapy Regions