✓ Last verified: March 24, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Harvard and Cornell-educated, UCLA-trained concierge psychiatrist offering intranasal ketamine therapy alongside comprehensive psychiatric care. Specializes in hard-to-treat cases and serves a diverse patient population including LGBTQ+ and creative professionals.
| Google Reviews | 5.0 stars |
| Location | Los Angeles, CA (Los Feliz) |
| Address | 4620 Hollywood Blvd, Los Angeles, CA 90027 |
| Phone | 323-546-4605 |
| Website | kylepsmithmd.com |
| Treatments | Intranasal Ketamine, Psychiatric Medication Management, Psychotherapy |
| Conditions | Treatment-Resistant Depression, Anxiety, PTSD, ADHD, Bipolar Disorder, BPD, Addiction |
| Cost | Concierge pricing; free 15-min consultation |
| Insurance | Contact for details |
| KAP Available? | Contact clinic – psychotherapy offered alongside ketamine |
| Clinical Lead | Dr. Kyle P. Smith, MD – Harvard/Cornell/UCLA-Trained Psychiatrist |
HealingMaps Take: Dr. Kyle P. Smith brings elite academic credentials — Harvard, Cornell, and UCLA — to a personalized concierge psychiatry practice in Los Feliz. His intranasal ketamine protocol focuses on the FDA-approved pathway, and his broad specialization across depression, anxiety, PTSD, ADHD, bipolar, BPD, and addiction means he can address complex, co-occurring conditions that other providers may struggle with. Dr. Smith is especially welcoming to LGBTQ+ patients, people of color, creatives, and first-time psychiatric patients. Note that availability is limited — he accepts new patients on a very selective basis — so the free 15-minute consultation is the best way to start.
Market Position: Kyle P Smith MD is a Spravato-certified clinic in the Angeles metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.
Industry pricing reference. Kyle P Smith MD’s posted price: Concierge pricing; free 15-min consultation. Contact the clinic for any package or sliding-scale options. The calculator above shows metro-level cost estimates across protocols.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | — |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
This 4-question summary is matched to the protocols and conditions Kyle P Smith MD treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Yes — Kyle P Smith MD offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.
Kyle P Smith MD treats depression via Spravato (FDA-approved for TRD). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Kyle P Smith MD treats PTSD. Spravato can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Yes — Kyle P Smith MD treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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