✓ Last verified: March 28, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Free initial consultation with a board-certified ER physician, offering both IV and IM ketamine with integrated psychotherapy support in the heart of Philadelphia’s Fishtown neighborhood.
$400–$450 per session; free initial consultation
Insurance
Private pay (contact clinic for details)
KAP Available?
Integration therapy provided with mental health provider after each session
Clinical Lead
Dr. Evan Husted, MD, MPH (Board-Certified Emergency Medicine)
HealingMaps Take: Mindstream Medicine brings ER-trained medical oversight to ketamine therapy, which means patients are in highly capable hands during treatment. The free initial consultation lowers the barrier to entry, and their protocol of 6 sessions over 3–6 weeks with integration therapy shows a commitment to lasting results rather than one-off infusions.
Market Position: Mindstream Medicine is an IV-ketamine-focused clinic in the Philadelphia metro — the most common cash-pay protocol in the HealingMaps verified directory.
Is Mindstream Medicine Right for You?
✓ Choose Mindstream Medicine if:
You want supervised IV ketamine with real-time medical monitoring
You prefer the shorter, lower-cost IM ketamine protocol
✗ Look elsewhere if:
You need Spravato (FDA-approved esketamine) covered by your insurance
You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy
You need insurance billing for treatment (this clinic is cash-pay)
Ketamine Protocols Compared — What’s Offered at Mindstream Medicine
Industry pricing reference. Mindstream Medicine’s posted price: $400–$450 per session; free initial consultation. Contact the clinic for any package or sliding-scale options. The calculator above shows metro-level cost estimates across protocols.
Protocol
Typical Industry Cost
Offered Here
IV Ketamine
$350–$650/session
✓ Yes
Spravato (esketamine)
$0–$250 copay (insured)
—
IM Ketamine
$250–$400/injection
✓ Yes
KAP (with therapist)
$400–$1,200/session
—
At-home troches
$150–$300/month
—
What to Expect at Your First Mindstream Medicine Appointment
Initial intake call — Brief medical history review, depression and anxiety screening, and medical clearance for IV ketamine. Call 267-383-7760 to schedule. Mindstream Medicine’s posted pricing: $400–$450 per session; free initial consultation.
Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Mindstream Medicine clinical team.
First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 2418 East York St, Philadelphia, PA 19125. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.
What to Ask on Your Mindstream Medicine Consult Call
How long has the Mindstream Medicine clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
Does Mindstream Medicine provide a superbill for out-of-network insurance reimbursement, and what’s a typical 6-session total cost including any follow-up?
How do you handle Highmark BCBS, Independence Blue Cross, and UPMC Spravato prior authorizations?
What does Mindstream Medicine recommend for patients who don’t respond to the standard 6-session acute series?
Philadelphia Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Pennsylvania, state-level prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
Adult depression in Pennsylvania: N/A
Frequent mental distress (14+ days per month): N/A
Adults lacking health insurance: N/A
Recent Philadelphia-area inquiries to HealingMaps: A growing stream of Pennsylvania residents have recently contacted us seeking ketamine care
Behind this data:HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,473 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
The U.S. ketamine therapy market is $3.4 billion today and projected to reach $6.9 billion by 2030 — more than doubling in a six-year window as access and awareness expand. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Questions about Mindstream Medicine
This 3-question summary is matched to the protocols and conditions Mindstream Medicine treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
What ketamine protocols does Mindstream Medicine offer?
Mindstream Medicine offers IV ketamine and IM ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.
Is Mindstream Medicine suited for treatment-resistant depression?
Mindstream Medicine treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Can Mindstream Medicine help with anxiety disorders?
Yes — Mindstream Medicine treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
Angelica Bottaro is a medical writer and researcher with a rich background in psychology and journalism. She holds a bachelor's degree in Psychology from Trent University and an Advanced Diploma in Journalism from Centennial College. Angelica has been a freelance writer since 2014, amassing bylines in various platforms like Very Well Health, The Good Men Project, MakeWell, and LymeTime among others. Although primarily a freelance writer, her educational background and career trajectory have positioned her as a voice in mental health discourse, highlighting systemic issues in mental health care through her writing.
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