✓ Last verified: February 14, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Mood Wellness Center takes a comprehensive approach to mental health in Annapolis, combining ketamine infusion therapy with psychiatric care and psychotherapy. The clinic focuses on treatment-resistant depression, anxiety, PTSD, and chronic pain, offering personalized protocols in a calming clinical environment.
| Review Scores | ⭐ 4.9 (40+ reviews) |
| Location | Annapolis, Maryland |
| Address | 927 West Street, Annapolis MD 21401 |
| Phone | (443) 940-6663 |
| Website | themoodcenter.com |
| Treatments | IV Ketamine Infusions, Psychiatric Evaluation, Psychotherapy, Medication Management |
| Conditions Treated | Treatment-Resistant Depression, Anxiety, PTSD, Chronic Pain, OCD, Bipolar Depression |
| Cost | $450–$550 per infusion (series packages available) |
| Insurance | Psychiatric services may be covered; ketamine infusions typically out-of-pocket |
| KAP Available? | Yes – Ketamine-Assisted Psychotherapy offered |
| Clinical Lead | Psychiatric team with MD oversight |
HealingMaps Take: Mood Wellness Center stands out in the Annapolis area for combining ketamine infusions with ongoing psychiatric care and psychotherapy under one roof. Their integrated model means patients aren’t just receiving infusions in isolation—they’re getting a full mental health support system. The clinic’s strong Google reviews and focus on treatment-resistant conditions make it a solid choice for patients in Maryland who haven’t found relief through conventional treatments.
Market Position: Mood Wellness Center treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.
Industry pricing reference. Mood Wellness Center has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | — |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | ✓ Yes |
| At-home troches | $150–$300/month | — |
This 4-question summary is matched to the protocols and conditions Mood Wellness Center treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Mood Wellness Center treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Mood Wellness Center treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — Mood Wellness Center treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Yes — Mood Wellness Center treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
TMS therapy is also available at this clinic, alongside ketamine and Spravato. Unlike cash-pay ketamine, TMS is covered by most major insurance plans for treatment-resistant depression. TMS is FDA-cleared for treatment-resistant depression (since 2008), OCD via Deep TMS, anxious depression, and adolescent MDD ages 15–21. Read our complete guide to TMS therapy for FDA-cleared conditions, device differences, insurance coverage by carrier, and what to expect at your first appointment. Browse verified TMS clinics in our directory.
View all REMS-certified Spravato clinics in Maryland and across the United States.
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