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✓ Last verified: March 19, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Newport Beach ketamine practice founded by Dr. Dina Seif, who brings 15+ years of emergency medicine ketamine experience. Known for its spa-like treatment environment and complimentary consultations with the doctor.

Review Scores4.9 stars, 15+ Yelp reviews; patients praise Dr. Seif’s warmth and spa-like environment
LocationNewport Beach, CA
Address4030 Birch St, Suite 106, Newport Beach, CA 92660
Phone(949) 478-4874
Websiteocketaminetherapy.com
TreatmentsIV Ketamine Infusion, IM Ketamine, TMS Therapy
Conditions TreatedTreatment-Resistant Depression, Anxiety, PTSD, PMDD, OCD, Chronic Pain
CostContact for pricing; free complimentary consultation with Dr. Seif
InsuranceSelf-pay; superbill provided for out-of-network reimbursement
Clinical LeadDr. Dina Seif, MD — Board-Certified Emergency Medicine, 15+ years ketamine experience

💡 No clinic-specific pricing posted? See our ketamine therapy cost guide for typical pricing ranges by treatment type and insurance pathways.

HealingMaps Take: OC Ketamine Therapy represents the physician-led boutique model done right. Dr. Dina Seif is board-certified in emergency medicine — meaning she has administered ketamine thousands of times in high-acuity settings before ever opening a clinic. That depth of hands-on experience with the medication is rare among ketamine clinic founders, many of whom come from psychiatry or anesthesiology backgrounds with less direct ketamine exposure. The Newport Beach location on Birch Street has been designed with patient comfort in mind — multiple reviewers compare it to a wellness spa rather than a medical clinic. The complimentary consultation with Dr. Seif herself (not a scheduler or intake coordinator) is a meaningful differentiator. This is a doctor who wants to evaluate every patient personally before treatment. The PMDD treatment offering is notably uncommon in the ketamine space and signals clinical sophistication.

Market Position: OC Ketamine Therapy is an IV-ketamine-focused clinic in the Beach metro — the most common cash-pay protocol in the HealingMaps verified directory.

Is OC Ketamine Therapy Right for You?

✓ Choose OC Ketamine Therapy if:

  • You want supervised IV ketamine with real-time medical monitoring
  • You prefer the shorter, lower-cost IM ketamine protocol
  • You’re treating co-occurring depression and PTSD

✗ Look elsewhere if:

  • You need Spravato (FDA-approved esketamine) covered by your insurance
  • You want ketamine-assisted psychotherapy (KAP) with integrated talk therapy

OC Ketamine Therapy Ketamine Cost Calculator

How Much Will Ketamine Therapy Cost?

Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$473–$810
Range: $405–$1,350/session
Estimated total program
$2,835–$4,860
Range: $2,430–$8,100/6-session series
Your estimate vs. national patient-reported median Based on national tracking, adjusted for Orange County, CA market
Select a treatment type to see pricing context.

Ketamine Protocols Compared — What’s Offered at OC Ketamine Therapy

Industry pricing reference. OC Ketamine Therapy has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

ProtocolTypical Industry CostOffered Here
IV Ketamine$350–$650/session✓ Yes
Spravato (esketamine)$0–$250 copay (insured)
IM Ketamine$250–$400/injection✓ Yes
KAP (with therapist)$400–$1,200/session
At-home troches$150–$300/month

What to Expect at Your First OC Ketamine Therapy Appointment

  1. Initial intake call — Brief medical history review, depression and anxiety screening, and medical clearance for IV ketamine. Call (949) 478-4874 to schedule.
  2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the OC Ketamine Therapy clinical team.
  3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 4030 Birch St, Suite 106, Newport Beach, CA 92660. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
  4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your OC Ketamine Therapy Consult Call

  • How long has the OC Ketamine Therapy clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
  • Does OC Ketamine Therapy provide a superbill for out-of-network insurance reimbursement, and what’s a typical 6-session total cost including any follow-up?
  • California’s psychedelic-therapy regulatory landscape is evolving — do you stay current with state Department of Public Health and Medical Board guidance on ketamine prescribing?
  • What does OC Ketamine Therapy recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about OC Ketamine Therapy

This 5-question summary is matched to the protocols and conditions OC Ketamine Therapy treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

What ketamine protocols does OC Ketamine Therapy offer?

OC Ketamine Therapy offers IV ketamine and IM ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.

Is OC Ketamine Therapy suited for treatment-resistant depression?

OC Ketamine Therapy treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does OC Ketamine Therapy treat chronic pain conditions?

Yes — OC Ketamine Therapy treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does OC Ketamine Therapy treat PTSD?

Yes — OC Ketamine Therapy treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can OC Ketamine Therapy help with anxiety disorders?

Yes — OC Ketamine Therapy treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

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Healing Maps Editorial Staff

Healing Maps Editorial Staff

View all posts by Healing Maps Editorial Staff

The Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.

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