✓ Last verified: March 19, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: Newport Beach ketamine practice founded by Dr. Dina Seif, who brings 15+ years of emergency medicine ketamine experience. Known for its spa-like treatment environment and complimentary consultations with the doctor.
| Review Scores | 4.9 stars, 15+ Yelp reviews; patients praise Dr. Seif’s warmth and spa-like environment |
| Location | Newport Beach, CA |
| Address | 4030 Birch St, Suite 106, Newport Beach, CA 92660 |
| Phone | (949) 478-4874 |
| Website | ocketaminetherapy.com |
| Treatments | IV Ketamine Infusion, IM Ketamine, TMS Therapy |
| Conditions Treated | Treatment-Resistant Depression, Anxiety, PTSD, PMDD, OCD, Chronic Pain |
| Cost | Contact for pricing; free complimentary consultation with Dr. Seif |
| Insurance | Self-pay; superbill provided for out-of-network reimbursement |
| Clinical Lead | Dr. Dina Seif, MD — Board-Certified Emergency Medicine, 15+ years ketamine experience |
💡 No clinic-specific pricing posted? See our ketamine therapy cost guide for typical pricing ranges by treatment type and insurance pathways.
HealingMaps Take: OC Ketamine Therapy represents the physician-led boutique model done right. Dr. Dina Seif is board-certified in emergency medicine — meaning she has administered ketamine thousands of times in high-acuity settings before ever opening a clinic. That depth of hands-on experience with the medication is rare among ketamine clinic founders, many of whom come from psychiatry or anesthesiology backgrounds with less direct ketamine exposure. The Newport Beach location on Birch Street has been designed with patient comfort in mind — multiple reviewers compare it to a wellness spa rather than a medical clinic. The complimentary consultation with Dr. Seif herself (not a scheduler or intake coordinator) is a meaningful differentiator. This is a doctor who wants to evaluate every patient personally before treatment. The PMDD treatment offering is notably uncommon in the ketamine space and signals clinical sophistication.
Market Position: OC Ketamine Therapy is an IV-ketamine-focused clinic in the Beach metro — the most common cash-pay protocol in the HealingMaps verified directory.
Industry pricing reference. OC Ketamine Therapy has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | ✓ Yes |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
This 5-question summary is matched to the protocols and conditions OC Ketamine Therapy treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
OC Ketamine Therapy offers IV ketamine and IM ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.
OC Ketamine Therapy treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — OC Ketamine Therapy treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — OC Ketamine Therapy treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
Yes — OC Ketamine Therapy treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.
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