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✓ Last verified: March 23, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff
Known For: South Orlando (Southpark Center Loop / Dr. Phillips / Sand Lake area) interventional psychiatry clinic with Spravato + IV/IM Ketamine + TMS under one roof. Part of multi-state Serenity Mental Health network. Extended weekday hours.
| Location | Orlando, Florida |
| Address | 9400 Southpark Center Loop Suite 450, Orlando, FL 32819 |
| Phone | (844) 310-1649 |
| Website | serenitymentalhealthcenters.com |
| Treatments | Spravato (Esketamine) + IV Ketamine + IM Ketamine + TMS Therapy |
| Conditions | Treatment-resistant depression, PTSD, anxiety, chronic pain, addiction |
| Cost | N/A (contact for pricing) |
| Insurance | Spravato typically insurance-billed; IV ketamine self-pay (FSA/HSA eligible) |
| KAP Available | No |
| Clinical Lead | Serenity Mental Health Centers psychiatric team |
HealingMaps Take: Serenity Mental Health Centers anchors the South Orlando / Dr. Phillips / Sand Lake area interventional psychiatry slot — meaningful for patients in south Orange County, Lake Nona, Dr. Phillips, and Universal-area neighborhoods. The combined Spravato + IV/IM Ketamine + TMS menu plus multi-state network operational depth (for Spravato prior-auth and insurance billing) makes it well-suited for treatment-resistant depression patients.
Market Position: Serenity Mental Health Centers occupies the South Orlando / Dr. Phillips multi-modality interventional psychiatry slot — distinct from the central Orlando, NW Orlando, and West Orlando practices.
Is Serenity Mental Health Centers Right for You?
✓ Choose Serenity Mental Health Centers if:
- You’re located in South Orlando, Dr. Phillips, Sand Lake, Universal area, or south Orange County
- You want Spravato + IV/IM Ketamine + TMS integrated within a single interventional psychiatry practice
- You have commercial insurance and a treatment-resistant depression diagnosis (Spravato + TMS pathways)
- You value multi-state network operational depth for Spravato prior-auth
✗ Look elsewhere if:
- You’re seeking ketamine-assisted psychotherapy (KAP) with structured integration
- You need a central Orlando, Baldwin Park, or NW Orlando location
Serenity Mental Health Centers Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$416–$714
Range: $357–$1,190/session
Estimated total program
$2,499–$4,283
Range: $2,142–$7,139/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at Serenity Mental Health Centers
Industry pricing reference. Serenity Mental Health Centers has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | ✓ Yes |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First Serenity Mental Health Centers Appointment
- Initial intake call — Insurance verification, Spravato prior authorization workflow if applicable, and clinical eligibility check. Call (844) 310-1649 to schedule.
- Medical evaluation — psychiatric assessment, vitals check, and review of current medications and prior treatment history with the Serenity Mental Health Centers clinical team.
- First treatment session — supervised ketamine session in a monitored treatment room at 9400 Southpark Center Loop Suite 450, Orlando, FL 32819.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session.
What to Ask on Your Serenity Mental Health Centers Consult Call
- How long has the Serenity Mental Health Centers clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- Walk me through your Spravato prior authorization process vs. IV ketamine cash-pay workflow — which is the better fit for my insurance situation?
- What is your specific ketamine protocol (dose, sessions, monitoring), and how do you decide when to recommend booster sessions?
- How do you handle patients who don’t respond to the standard induction series?
Orlando Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Orange County (South Orlando / Dr. Phillips), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Orange County (South Orlando / Dr. Phillips): 16.7%
- Frequent mental distress (14+ days per month): 13.4%
- Adults lacking health insurance: 8.7%
- Orange County (South Orlando / Dr. Phillips) population: 2,673,376 · median household income $70,683
- Recent Orlando-area inquiries to HealingMaps: A growing stream of Orlando-area residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,800 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“Serenity’s South Orlando location was right for me — Dr. Phillips area access without commuting downtown. Having Spravato AND TMS at the same office meant my treatment plan was coordinated by one team, and the network depth showed in how smoothly the insurance prior auth went.”
About Serenity Mental Health Centers
Serenity Mental Health Centers Orlando operates from 9400 Southpark Center Loop, Suite 450 in Orlando (32819) — a South Orlando / Dr. Phillips / Sand Lake area location accessible from south Orange County, Lake Nona, Dr. Phillips, Williamsburg, and the Universal area corridor. The clinic is part of the multi-state Serenity Mental Health Centers network.
Serenity is one of the few Orlando clinics offering Spravato (esketamine nasal spray), IV ketamine, IM ketamine, AND TMS (transcranial magnetic stimulation) within a single interventional psychiatry practice — meaningful for patients whose treatment plan may involve more than one modality. Both Spravato and TMS are FDA-approved for treatment-resistant depression and typically covered by commercial insurance plans.
Conditions treated include treatment-resistant depression, PTSD, anxiety disorders, addiction (substance use disorder), and chronic pain. The clinic also offers ADHD testing and management, psychiatric medication management, and comprehensive mental health care alongside the interventional services.
Multi-state network operational depth brings standardized protocols and dedicated Spravato prior-authorization workflows — meaningful for patients navigating commercial insurance billing. To schedule, call (844) 310-1649 or visit serenitymentalhealthcenters.com.
Patient Questions about Serenity Mental Health Centers
This 5-question summary is matched to the protocols and conditions Serenity Mental Health Centers treats. Editorial responses are HealingMaps-authored.
What ketamine protocols does Serenity Mental Health Centers offer?
Serenity Mental Health Centers offers Spravato (Esketamine) + IV Ketamine + IM Ketamine + TMS Therapy. Confirm specific dosing schedules during your consult.
Does Serenity Mental Health Centers offer Spravato (esketamine)?
Yes — Serenity Mental Health Centers offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose.
Does Serenity Mental Health Centers offer ketamine-assisted psychotherapy (KAP)?
Serenity Mental Health Centers operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
Is Serenity Mental Health Centers suited for treatment-resistant depression?
Serenity Mental Health Centers treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Can Serenity Mental Health Centers help with anxiety disorders?
Yes — Serenity Mental Health Centers treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in Florida and across the United States.
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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