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✓ Edited by Angelica Bottaro for HealingMaps Editorial Staff
Known For: The Metro East’s interventional psychiatry anchor — a 12-provider practice established in 2004 running Spravato, IV ketamine, TMS including the SWIFT accelerated protocol, and neurofeedback, minutes from Edwardsville and Collinsville under founder Sanjay K. Nigam, MD.
| Location | Maryville, Illinois |
| Address | 6805 State Route 162, Maryville, IL 62062 |
| Phone | (618) 288-5019 |
| Website | sia-llc.net |
| Treatments | Spravato (Esketamine, REMS-certified) + IV Ketamine + TMS Therapy (including SWIFT accelerated protocol) + Neurofeedback |
| Conditions | Treatment-resistant depression, major depressive disorder, anxiety, and PTSD |
| Cost | N/A (contact for pricing) |
| Insurance | Spravato typically insurance-billed; IV ketamine self-pay (FSA/HSA eligible) |
| KAP Available | No |
| Clinical Lead | Sanjay K. Nigam, MD (Founder and President, board-certified psychiatrist; Anna Zarlingo, FNP leads the Spravato and ketamine clinic; 12-provider practice) |
HealingMaps Take: Southern Illinois Associates is the answer for the Illinois side of the St. Louis metro: the only verified practice in the Metro East running the full interventional stack — insurance-billed Spravato, IV ketamine for patients who need the infusion route, TMS with an accelerated SWIFT option, and neurofeedback — inside a 12-provider psychiatric group that has operated since 2004. Anna Zarlingo, FNP runs the day-to-day Spravato and ketamine clinic with founder Sanjay Nigam, MD directing. A walk-in clinic and two-decade local history make it the region’s most established door.
Market Position: SIA holds the full-stack interventional slot in the Metro East market — the only verified Spravato-plus-IV-ketamine-plus-TMS practice between the Mississippi River and Edwardsville, differentiated by its 12-provider depth and 2004-founding tenure.
Is SIA Right for You?
✓ Choose SIA if:
- You’re in Edwardsville, Collinsville, Glen Carbon, Troy, or anywhere in the Metro East
- You want insurance-billed Spravato without crossing the river
- You may want IV ketamine or TMS — all options run in one practice
- The SWIFT accelerated TMS protocol interests you
- A large, established group practice with walk-in access matters to you
✗ Look elsewhere if:
- You’re seeking formal ketamine-assisted psychotherapy sessions
- You want at-home or oral ketamine
- You’re on the Missouri side and west county is closer — see the St. Louis Spravato providers
SIA Ketamine Cost Calculator
How Much Will Ketamine Therapy Cost?
Estimate your out-of-pocket range based on patient-reported pricing and HealingMaps proprietary clinic data.
Estimated per session
$416–$714
Range: $357–$1,190/session
Estimated total program
$2,499–$4,283
Range: $2,142–$7,139/6-session series
Select a treatment type to see pricing context.
Ketamine Protocols Compared — What’s Offered at SIA
Industry pricing reference. SIA has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
What to Expect at Your First SIA Appointment
- Initial intake call — Insurance verification, Spravato prior authorization workflow if applicable, and clinical eligibility check. Call (618) 288-5019 to schedule.
- Medical evaluation — psychiatric assessment, vitals check, and review of current medications and prior treatment history with the SIA clinical team.
- First treatment session — supervised ketamine session in a monitored treatment room at 6805 State Route 162, Maryville, IL 62062.
- Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session.
What to Ask on Your SIA Consult Call
- How long has the SIA clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
- Walk me through your Spravato prior authorization process vs. IV ketamine cash-pay workflow — which is the better fit for my insurance situation?
- What is your specific ketamine protocol (dose, sessions, monitoring), and how do you decide when to recommend booster sessions?
- How do you handle patients who don’t respond to the standard induction series?
Maryville Ketamine Market Snapshot
Sources: CDC PLACES 2023 (Madison County (Maryville — Metro East, serving Edwardsville and Collinsville), crude prevalence) · U.S. Census ACS 5 Year · HealingMaps proprietary patient inquiry data.
- Adult depression in Madison County (Maryville — Metro East, serving Edwardsville and Collinsville): 16.7%
- Frequent mental distress (14+ days per month): 13.4%
- Adults lacking health insurance: 8.7%
- Madison County (Maryville — Metro East, serving Edwardsville and Collinsville) population: 2,820,000 · median household income $70,000
- Recent Maryville-area inquiries to HealingMaps: A growing stream of Maryville-area residents have recently contacted us seeking ketamine care
Behind this data: HealingMaps has analyzed 23,496 patient inquiries (Oct 2022 – Mar 2026), mapped 1,800 verified clinics across 3,142 counties, scraped 132 clinic pricing pages, and collected 658 practitioner survey responses. This snapshot reflects our multi-source methodology.
From the 2026 Ketamine Industry Report
44.9% of patients cite access as the #1 barrier to treatment — the largest single obstacle to ketamine therapy in the HealingMaps corpus, outranking cost, stigma, and side-effect concerns. Source: HealingMaps 2026 Ketamine Clinic Intelligence Report — drawn from 23,496 patient inquiries and 132 clinic website analyses.
Patient Review
“Living in Edwardsville, everything I found was across the river until SIA. They ran my Spravato approval, and when we later added a short TMS course it was the accelerated version — three weeks instead of six. Twenty years in the area shows in how smoothly the place runs.”
About SIA
Southern Illinois Associates operates at 6805 State Route 162 in Maryville, Illinois (62062), about five miles from Collinsville and eight from Edwardsville, explicitly serving the Metro East side of the St. Louis metro. Founded in 2004 by board-certified psychiatrist Sanjay K. Nigam, MD, the practice now spans 12 providers, with Anna Zarlingo, FNP leading day-to-day operations of the Spravato and ketamine clinic. Hours run Monday through Friday 8:00am to 5:00pm, with a walk-in clinic from 8:00am to 4:00pm.
The interventional lineup is the region’s broadest: Spravato (esketamine) administered under the FDA REMS protocol, IV ketamine infusions, TMS therapy including the SWIFT accelerated protocol, and neurofeedback — all alongside full psychiatric care.
Spravato and TMS are typically insurance-billable for qualifying diagnoses; IV ketamine is generally self-pay. Conditions treated include treatment-resistant depression, major depressive disorder, anxiety, and PTSD.
To schedule, call (618) 288-5019 or visit sia-llc.net.
Patient Questions about SIA
This 5-question summary is matched to the protocols and conditions SIA treats. Editorial responses are HealingMaps-authored.
What ketamine protocols does SIA offer?
SIA offers Spravato (Esketamine, REMS-certified) + IV Ketamine + TMS Therapy (including SWIFT accelerated protocol) + Neurofeedback. Confirm specific dosing schedules during your consult.
Does SIA offer Spravato (esketamine)?
Yes — SIA offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose.
Does SIA offer ketamine-assisted psychotherapy (KAP)?
SIA operates a medical-model program. Patients seeking explicit KAP with a licensed integration therapist should evaluate practices that pair the dosing experience with structured therapy.
Is SIA suited for treatment-resistant depression?
SIA treats treatment-resistant depression. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates.
Can SIA help with anxiety disorders?
Yes — SIA treats anxiety disorders. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines.
View all REMS-certified Spravato clinics in Illinois and across the United States.
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Healing Maps Editorial Staff
View all posts by Healing Maps Editorial StaffThe Healing Maps Editorial Team has decades of experience across all facets of the psychedelic industry. From assessing studies and clinic research, to working with clinician's and clinics, we help provide data-backed information to psychedelic-curious individuals across the globe.
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