Spruce Mental Health – Jackson, Wyoming Ketamine Clinics

Known For: Integrative psychiatric clinic offering KAP (ketamine-assisted psychotherapy) in Jackson Hole. Therapy-focused ketamine practice with psychedelic integration services.

HealingMaps Take: Spruce Mental Health represents a fundamentally different approach to ketamine treatment in Wyoming. While most ketamine clinics in the region focus on IV infusions — a medical procedure administered in a clinical setting — Spruce offers ketamine-assisted psychotherapy (KAP), where ketamine is used as a tool to deepen and accelerate therapeutic work. This is not an infusion clinic; it is a psychiatric practice that integrates ketamine into a broader psychotherapeutic framework. The distinction matters enormously for patients whose conditions — trauma, PTSD, alcohol use disorder — are best treated through a combination of pharmacological and psychological intervention. The addition of psychedelic integration services signals a practice that is philosophically aligned with the emerging psychedelic therapy movement, not just offering ketamine as an off-label antidepressant. Located in Jackson Hole, Spruce serves a community that values holistic, integrative health approaches. The fee-for-service model and explicit non-acceptance of insurance reflect the premium, boutique nature of the practice. For patients who want therapy-embedded ketamine treatment rather than a standalone infusion, Spruce Mental Health is the only option in Wyoming.

Patient Review

“Spruce’s approach was completely different from what I expected. The ketamine was part of a therapeutic process, not just an IV drip. The integration work before and after each session made all the difference in my healing.”

About Spruce Mental Health

Spruce Mental Health is an integrative psychiatric practice located at 580 E Broadway Ave in Jackson, Wyoming. The clinic offers ketamine-assisted psychotherapy (KAP), psychedelic integration, psychiatry, psychotherapy, and medication management. The practice treats depression, anxiety, PTSD, trauma, and alcohol use disorder through a multi-provider psychiatric team. Spruce operates on a fee-for-service model and does not accept insurance, Medicare, or Medicaid. The practice is distinct from IV infusion clinics, focusing instead on therapy-embedded ketamine treatment within a broader psychiatric care model.

For more on how ketamine therapy works, see our complete guide to ketamine therapy.

What People Like

The only KAP (ketamine-assisted psychotherapy) provider in Wyoming — a fundamentally different and often more therapeutically effective approach than infusion-only clinics. Psychedelic integration services reflect cutting-edge treatment philosophy. Full psychiatric services (psychiatry, psychotherapy, medication management) are available alongside KAP. The Jackson Hole location serves a community that values holistic health. Multi-provider team reduces single-provider bottleneck risks.

What People Don’t Like

Insurance is not accepted — no insurance, Medicare, or Medicaid — making treatment entirely out-of-pocket. IV ketamine infusions are not offered for patients who prefer the medical model. Specific pricing is not published online. Jackson is geographically isolated — patients from other parts of Wyoming face long drives. The fee-for-service model in a high-cost-of-living area may result in premium pricing.

Getting Started at Spruce Mental Health

Visit sprucejh.com to inquire about scheduling. The clinic is at 580 E Broadway Ave, Jackson, WY 83001. Note that insurance is not accepted — all services are fee-for-service. Ask about the KAP protocol and what to expect during your initial consultation.

Learn more about the evidence behind ketamine for depression at the National Institute of Mental Health.

Learn more about this treatment:

• IV Ketamine vs Spravato: A Provider’s Guide to Both Treatment Paths
• IV Ketamine Shows Superior Results Over Nasal Esketamine for Treatment Resistant Depression

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