✓ Last verified: February 7, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: The Costello Clinic in Highland Village offers ketamine infusion therapy in the Denton County area between Dallas and Denton. The clinic provides personalized ketamine protocols for depression, anxiety, PTSD, and chronic pain, serving Lewisville, Flower Mound, Highland Village, and surrounding communities.
| Google Reviews | ⭐ Denton County / Highland Village |
| Location | Highland Village, Texas |
| Address | 2820 Village Pkwy, Suite 620, Highland Village, TX 75077 |
| Phone | (972) 317-2082 |
| Website | costelloclinic.com |
| Treatments | Ketamine Infusions |
| Conditions Treated | Depression, Anxiety, PTSD, Chronic Pain |
| Cost | Contact clinic for pricing |
| Insurance | Contact clinic for details |
| KAP Available | Not specified |
| Clinical Lead | Contact clinic |
HealingMaps Take: The Costello Clinic gives Denton County residents a local ketamine option in Highland Village. Convenient for the I-35E corridor between Dallas and Denton.
Market Position: The Costello Clinic treats both depression and PTSD — the two most common ketamine therapy indications, accounting for 34% of HealingMaps patient inquiries.
⚠ FDA-cleared indications for TMS therapy: treatment-resistant major depressive disorder (MDD), obsessive-compulsive disorder (OCD, Deep TMS only), anxious depression, short-term smoking cessation, and adolescent MDD (ages 15–21). Use of TMS for other conditions including PTSD, bipolar depression, fibromyalgia, and other indications is off-label — not currently FDA-cleared for those specific indications. Discuss your condition with the clinic to understand insurance coverage and clinical evidence.
Industry pricing reference. The Costello Clinic has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine Infusion | $350–$650/session | ✓ |
| Spravato (esketamine) | $0–$250 copay (insured) | — |
| IM Ketamine | $250–$400/injection | — |
| KAP (with integrated talk therapy) | $400–$1,200/session | — |
| At-home oral troches | $150–$300/month | — |
This 2-question summary is matched to the protocols and conditions The Costello Clinic treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Yes — The Costello Clinic treats chronic pain. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — The Costello Clinic treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
This clinic also offers TMS therapy alongside ketamine. TMS sessions take 19 to 37 minutes (or 3 minutes for the iTBS protocol), with no anesthesia, sedation, or controlled-substance handling. This clinic uses BrainsWay Deep TMS, the only TMS device with standalone FDA clearance for OCD via the H7 coil. Read our complete guide to TMS therapy for FDA-cleared conditions, device differences, insurance coverage by carrier, and what to expect at your first appointment. Browse verified TMS clinics in our directory.
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