Zephyr Medical – Brooklyn, New York Ketamine Clinics, Spravato Clinics

✓ Last verified: March 29, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: One of Brooklyn’s largest IV ketamine centers, combining mental health and pain management under board-certified specialists.

💡 No clinic-specific pricing posted? See our ketamine therapy cost guide for typical pricing ranges by treatment type and insurance pathways.

HealingMaps Take: Zephyr Medical has established itself as one of the largest IV ketamine centers in Brooklyn, offering a broad infusion menu that includes ketamine, Spravato, NAD+, and pain-specific protocols. Led by board-certified pain management specialists Dr. Benjamin Portal and Dr. Asher Goldstein, the clinic bridges the gap between mental health and chronic pain treatment — making it an especially strong choice for patients dealing with both.

Market Position: Zephyr Medical is a Spravato-certified clinic in the Brooklyn metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.

Zephyr Medical Ketamine Cost Calculator

Ketamine Protocols Compared — What’s Offered at Zephyr Medical

Industry pricing reference. Zephyr Medical has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

What to Expect at Your First Zephyr Medical Appointment

1. Initial intake call — Insurance verification, prior authorization workflow (Spravato requires documentation of failure on at least two antidepressant trials), and clinical eligibility check. Call (646) 727-9977 to schedule.
2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Zephyr Medical clinical team.
3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 111 Livingston St, Suite 1901, Brooklyn, NY 11201. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your Zephyr Medical Consult Call

• How long has the Zephyr Medical clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
• Walk me through Zephyr Medical’s Spravato prior authorization process versus your IV ketamine cash-pay or superbill workflow — which is the better fit for my insurance situation?
• Which New York commercial insurers (Aetna, UnitedHealthcare, Empire BCBS, Oxford, Healthfirst) have you successfully obtained Spravato prior authorization through?
• What does Zephyr Medical recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about Zephyr Medical

This 6-question summary is matched to the protocols and conditions Zephyr Medical treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

What ketamine protocols does Zephyr Medical offer?

Zephyr Medical offers Spravato and IV ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.

Does Zephyr Medical offer Spravato (esketamine)?

Yes — Zephyr Medical offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.

Is Zephyr Medical suited for treatment-resistant depression?

Zephyr Medical treats depression via Spravato (FDA-approved for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Zephyr Medical treat chronic pain conditions?

Yes — Zephyr Medical treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does Zephyr Medical treat PTSD?

Yes — Zephyr Medical treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Zephyr Medical help with anxiety disorders?

Yes — Zephyr Medical treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

View all REMS-certified Spravato clinics in New York and across the United States.

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