Breakthru Clinic – Tampa, Florida Ketamine Clinics

✓ Last verified: April 24, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: Breakthru Clinic (TampaPainMD) is led by Dr. Kalava, a double board-certified, Mayo Clinic fellowship-trained anesthesiologist and pain physician. The clinic claims to be the first in the world to offer IV ketamine bolus treatment for depression, anxiety, and PTSD, and is Florida’s first acute pain clinic. They also offer nitrous oxide therapy and IV lidocaine infusions for chronic pain and fibromyalgia.

HealingMaps Take: Breakthru Clinic stands out for its pioneering IV ketamine bolus protocol and Dr. Kalava’s exceptional credentials — Mayo Clinic training and double board certification in anesthesiology and pain medicine. The clinic’s multimodal approach (ketamine, nitrous oxide, lidocaine, laser therapy) gives patients multiple pathways to relief. Patients consistently praise the clean, relaxing environment and minimal wait times.

Market Position: Breakthru Clinic is an IV-ketamine-focused clinic in the Tampa metro — the most common cash-pay protocol in the HealingMaps verified directory.

Breakthru Clinic Ketamine Cost Calculator

Ketamine Protocols Compared — What’s Offered at Breakthru Clinic

Industry pricing reference. Breakthru Clinic has not published specific per-session pricing — contact the clinic directly for a quote. The calculator above shows typical metro-level cost estimates across protocols, not this clinic’s specific prices.

What to Expect at Your First Breakthru Clinic Appointment

1. Initial intake call — Brief medical history review, depression and anxiety screening, and medical clearance for IV ketamine. Call (813) 533-6259 to schedule.
2. Medical evaluation — in-person or telehealth psychiatric assessment, vitals check, and review of current medications with the Breakthru Clinic clinical team.
3. First treatment session — supervised IV ketamine infusion in a private treatment room, lasting approximately 60–90 minutes (40-minute infusion + recovery). Sessions are held at 375 S 12th St, Tampa, FL 33602. You’ll have a comfortable chair or recliner, dim lighting, and direct medical monitoring throughout.
4. Recovery and follow-up — observation period after dosing, mood check-in with the clinical team, and scheduling your next session. Arrange for a ride home; do not drive for 24 hours after your IV session.

What to Ask on Your Breakthru Clinic Consult Call

• How long has the Breakthru Clinic clinical team been delivering ketamine therapy, and what specialty training do your providers hold?
• Does Breakthru Clinic provide a superbill for out-of-network insurance reimbursement, and what’s a typical 6-session total cost including any follow-up?
• Are you set up for both commercial insurance Spravato pathways and cash-pay IV ketamine, or primarily one?
• What does Breakthru Clinic recommend for patients who don’t respond to the standard 6-session acute series?

Patient Questions about Breakthru Clinic

This 4-question summary is matched to the protocols and conditions Breakthru Clinic treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.

Is Breakthru Clinic suited for treatment-resistant depression?

Breakthru Clinic treats depression via IV ketamine (off-label, evidence-based). Insurance coverage is rare for IV/KAP — most patients pay out of pocket. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.

Does Breakthru Clinic treat chronic pain conditions?

Yes — Breakthru Clinic treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.

Does Breakthru Clinic treat PTSD?

Yes — Breakthru Clinic treats PTSD. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.

Can Breakthru Clinic help with anxiety disorders?

Yes — Breakthru Clinic treats anxiety, including generalized anxiety, social anxiety, and panic disorder. The evidence base for ketamine in anxiety is less robust than for depression, but it can be a meaningful option for patients who haven’t responded to SSRIs or benzodiazepines. Worth asking which of their protocols they typically recommend for anxiety-primary patients.

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