✓ Last verified: March 9, 2026 — Edited & verified by Angelica Bottaro for HealingMaps Editorial Staff

Known For: One of the Tampa Bay area’s most experienced ketamine clinics with over 7,000 infusions performed, led by Dr. Ashraf Hanna — a pioneer in IV ketamine for chronic pain.
| Google Reviews | 3.5/5 (231 reviews) |
| Location | Clearwater, FL |
| Address | 3280 McMullen Booth Rd., Suite 240, Clearwater, FL 33761 |
| Phone | (727) 797-7463 |
| Website | floridaspineinstitute.com |
| Treatments | IV Ketamine Infusion, Low-Dose Ketamine, Intranasal Ketamine |
| Conditions | CRPS/RSD, Fibromyalgia, Neuropathy, Depression, PTSD, OCD |
| Cost | N/A |
| Insurance | Contact clinic for details |
| KAP Available? | No — pain-focused infusion program |
| Clinical Lead | Dr. Ashraf Hanna |
HealingMaps Take: Florida Spine Institute stands out for sheer volume — over 7,000 ketamine infusions performed under Dr. Hanna’s direction. This is primarily a chronic pain clinic, so patients seeking ketamine for depression or anxiety will find the approach more medically focused than psychotherapy-integrated.
Market Position: Florida Spine Institute is a Spravato-certified clinic in the Clearwater metro. Spravato (esketamine) is the FDA-approved ketamine treatment that most commercial insurance plans cover after prior authorization — unlike cash-pay IV ketamine.
Industry pricing reference. Florida Spine Institute’s posted price: N/A. Contact the clinic for any package or sliding-scale options. The calculator above shows metro-level cost estimates across protocols.
| Protocol | Typical Industry Cost | Offered Here |
|---|---|---|
| IV Ketamine | $350–$650/session | ✓ Yes |
| Spravato (esketamine) | $0–$250 copay (insured) | ✓ Yes |
| IM Ketamine | $250–$400/injection | — |
| KAP (with therapist) | $400–$1,200/session | — |
| At-home troches | $150–$300/month | — |
This 5-question summary is matched to the protocols and conditions Florida Spine Institute treats. Editorial responses are HealingMaps-authored, grounded in our 2026 Ketamine Clinic Intelligence Report.
Florida Spine Institute offers Spravato and IV ketamine — a 2-protocol practice. Patients can switch between or combine modalities without changing providers. Confirm specific dosing schedules and which protocols are recommended for your condition during your consult.
Yes — Florida Spine Institute offers Spravato, which means they’re FDA REMS-certified and maintain the required two-hour in-office monitoring window after each dose. Spravato is the primary insurance-covered ketamine option for treatment-resistant depression. Worth confirming the prior-authorization timeline before booking your first session.
Florida Spine Institute treats depression via Spravato (FDA-approved for TRD), and IV ketamine (off-label, evidence-based). The Spravato pathway is the most likely to obtain commercial insurance coverage. TRD is typically defined as two or more prior antidepressant trials without sufficient response — patients meeting that bar are best candidates here.
Yes — Florida Spine Institute treats chronic pain. They use IV ketamine for pain, which typically means longer infusion times and higher cumulative doses than mental-health protocols. Common indications include complex regional pain syndrome (CRPS), fibromyalgia, and certain neuropathic pain syndromes. Pain pricing varies significantly by structure: per-infusion vs. multi-day inpatient packages — verify how this clinic structures their billing.
Yes — Florida Spine Institute treats PTSD. Both Spravato and IV ketamine can be used for trauma. Ketamine for trauma differs from depression treatment: dosing is often lower per session, and pairing the protocol with trauma-focused therapy between sessions is common. A reasonable consult question: whether PTSD patients here typically use ketamine alone or alongside an outside therapist.
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