5 Best Ketamine Clinics in Boulder (2026) — Verified & Reviewed
Best Ketamine Clinics in Boulder
Boulder’s interventional-psychiatry market reflects the city itself — a college town with a wellness-and-tech overlay where one ranked clinic offers cannabis-assisted psychotherapy alongside ketamine, and another runs an Intensive Outpatient Program (IOP) integrating Stellate Ganglion Block + IV + IM ketamine + Deep TMS. Five ranked clinics span a clinical-philosophy spread that’s deeper than most metros twice Boulder’s size.
3 things to know about Boulder ketamine access in 2026
1. Center for Medicinal Mindfulness offers cannabis-assisted psychotherapy alongside ketamine — a national rarity. Center for Medicinal Mindfulness, founded by Daniel McQueen, offers ketamine-assisted psychotherapy via oral lozenges and IM injection AND cannabis-assisted psychotherapy. Cannabis-assisted psychotherapy is legal in Colorado but remains rare nationally — Boulder is one of the few U.S. cities where this modality is available within a structured KAP-style framework. KAP sessions typically run 3 hours, integrating prep, dosing, and immediate post-session work.
2. Plus by APN runs an IOP integrating Stellate Ganglion Block + IV + IM ketamine + Deep TMS — uncommon outside major academic centers. Plus by APN (All Points North) offers an Intensive Outpatient Program combining Stellate Ganglion Block (SGB), IV ketamine, IM ketamine, Deep TMS, and full medication management — in-network with Anthem BCBS, Aetna, TRICARE, and UHC/Optum. SGB is an interventional-anesthesia procedure used for PTSD; combining it with ketamine modalities and Deep TMS in a structured IOP framework is uncommon outside major academic medical centers. Ketamine pricing starts at $340/session.
3. Boulder has multi-modal KAP-only options unavailable in most U.S. metros. Sky Medicine pairs an LCSW (Sara Lewis, PhD) with an acupuncturist/LMT (Brett Knowles) for KAP integrated with contemplative psychotherapy and somatic therapy. Boulder Ketamine offers psychiatrist-led group ketamine sessions designed to keep costs accessible. Most U.S. metros have one or two KAP-integrated options at most; Boulder’s three (Sky, Center for Medicinal Mindfulness, Boulder Ketamine) plus Integrative Psychiatry Center represents an unusual KAP market depth.
Boulder Ketamine Access Snapshot
- Verified ranked clinics in metro: 5 across Boulder — unusually deep KAP-and-interventional-psychiatry market for a college metro of ~330K
- Modality mix: IV ketamine, IM ketamine, oral lozenge ketamine, Spravato (esketamine), Ketamine-Assisted Psychotherapy (KAP), cannabis-assisted psychotherapy, Stellate Ganglion Block (SGB), Deep TMS, IOP, group ketamine sessions, contemplative + somatic + acupuncture integration
- Plus by APN published pricing: Ketamine starting at $340/session — in-network with Anthem BCBS, Aetna, TRICARE, UHC/Optum
- National-rarity modality: Cannabis-assisted psychotherapy at Center for Medicinal Mindfulness — legal in Colorado, available within structured KAP-style framework, rare nationally
- IOP-integrated interventional-psychiatry stack at Plus by APN: SGB + IV + IM ketamine + Deep TMS in one Intensive Outpatient Program — uncommon outside major academic medical centers
- National benchmark: Median patient-reported IV ketamine session cost is $350; Plus by APN’s $340 starting rate sits at the U.S. median
- Group ketamine option: Boulder Ketamine offers psychiatrist-led group ketamine sessions — keeps costs accessible for patients who find peer-supported integration meaningful
- Regional draw: Boulder pulls from CU Boulder student population, Denver-metro patients seeking KAP/cannabis-assisted depth, and Front Range communities — Niwot, Lyons, Longmont, Louisville-Lafayette
Behind this data: Where this data comes from: FDA Spravato REMS provider data, HealingMaps’ verified Boulder clinic listings, Colorado state regulatory framework for cannabis-assisted psychotherapy, CDC BRFSS Colorado mental-health prevalence, U.S. Census ACS for Boulder County, and HealingMaps’ national IV ketamine pricing scrape (n=65 clinics with confirmed per-session rates).
What this means for you: Boulder runs against typical mid-tier U.S. ketamine markets — therapy-frame KAP and cannabis-assisted psychotherapy carry more weight than Spravato access; IOP-integrated interventional-psychiatry stacks are unusually accessible; group ketamine and contemplative-somatic frameworks are real options. The practical decision turns on therapeutic philosophy match more than insurance fit. Use the calculator below to model your scenario.
Boulder, Colorado Ketamine Treatment Cost Calculator
Boulder Ketamine Clinics At-a-Glance
| Clinic | Modalities | Clinical Lead | Insurance | Per-Session Cost |
|---|---|---|---|---|
| Plus by APN | IV + IM Ketamine + Deep TMS + SGB + IOP + Med Mgmt | All Points North Clinical Team | Anthem BCBS, Aetna, TRICARE, UHC/Optum | Ketamine starting $340/session |
| Sky Medicine | KAP + Contemplative Psychotherapy + Somatic + Acupuncture | Sara Lewis, PhD, LCSW & Brett Knowles, MA, LAc, LMT | Contact clinic | Contact for pricing |
| Center for Medicinal Mindfulness | KAP (Oral Lozenges + IM) + Cannabis-Assisted Psychotherapy | Daniel McQueen, Founder & Executive Director | Private pay | Contact; KAP sessions ~3 hours |
| Integrative Psychiatry Center of Boulder | Spravato + Integrative Psychiatry | Integrative Psychiatry Centers clinical team | Spravato may be covered | Contact clinic |
| Boulder Ketamine | IV/Group Ketamine | Psychiatrist-led + licensed psychotherapists | Contact clinic | Group format keeps costs accessible |
1. Plus by APN
| Review Scores | ⭐ 4.7 (20+ reviews) |
| Location | Boulder, Colorado |
| Address | 1360 Walnut Street, Suite 110, Boulder, CO |
| Phone | (855) 510-4585 |
| Website | plusapn.com |
| Treatments | IV Ketamine, IM Ketamine, Deep TMS, Stellate Ganglion Block (SGB), IOP, Medication Management |
| Conditions Treated | Depression, Anxiety, PTSD, Trauma, OCD, Suicidal Ideation, Chronic Stress |
| Cost | Ketamine starting at $340/session |
| Insurance | In-network: Anthem BCBS, Aetna, TRICARE, UHC/Optum |
| KAP Available? | Contact clinic for details |
| Clinical Lead | All Points North Clinical Team |
Known For: Plus by APN (All Points North) in Boulder offers a modern, multi-modal approach to mental health treatment. The clinic provides IV and IM ketamine therapy alongside deep TMS, stellate ganglion block (SGB), intensive outpatient programs, and integrative psychiatry. In-network with major insurers including Anthem, Aetna, TRICARE, and UHC/Optum, Plus by APN makes advanced treatments more financially accessible.
Why We Picked Them: Plus by APN brings a multi-modality interventional psychiatry suite to Boulder — IV ketamine, IM ketamine, Deep TMS, AND Stellate Ganglion Block (SGB) for PTSD. That credential combination is rare nationally and gives complex-case patients real flexibility within a single clinical home.
SGB availability is particularly valuable for combat-veteran PTSD patients who have failed traditional treatment paths.
2. Sky Medicine
| Review Scores | ⭐ 5.0 (limited reviews) |
| Location | Boulder, Colorado |
| Address | 2133 13th St, Suite 100, Boulder, CO 80302 |
| Phone | (303) 900-8924 |
| Website | skymedicine.co |
| Treatments | Ketamine-Assisted Psychotherapy (KAP), Contemplative Psychotherapy, Somatic Therapy, Acupuncture, Bodywork |
| Conditions Treated | Treatment-Resistant Depression, Anxiety, Trauma, OCD, Chronic Pain |
| Cost | Contact for pricing |
| Insurance | Contact clinic for details |
| KAP Available? | Yes – Core offering with alternating medicine and integration sessions |
| Clinical Lead | Sara Lewis, PhD, LCSW & Brett Knowles, MA, LAc, LMT |
Known For: Sky Medicine in Boulder is a collaborative practice co-founded by Sara Lewis, PhD, LCSW and Brett Knowles, MA, LAc, LMT, bringing together contemplative psychotherapy, somatic therapy, acupuncture, and ketamine-assisted psychotherapy (KAP). The clinic’s unique integrative model weaves Chinese medicine, somatic trauma therapy, and contemplative psychotherapy into the psychedelic preparation, journey, and integration process.
Why We Picked Them: Sky Medicine offers Boulder’s most contemplative-tradition-aligned KAP practice — ketamine-assisted psychotherapy paired with contemplative psychotherapy frameworks rooted in Buddhist and mindfulness traditions. The therapeutic-depth model fits Boulder’s patient demographic better than pure medical infusion clinics.
Particularly well-suited for patients seeking a meaning-making framework alongside their pharmacological treatment.
3. Center for Medicinal Mindfulness
| Review Scores | ⭐ Mixed Reviews (Limited Sample) |
| Location | Boulder, Colorado |
| Address | 75 Manhattan Drive, Suite 106, Boulder, CO 80303 |
| Phone | (303) 562-4128 |
| Website | medicinalmindfulness.org |
| Treatments | Ketamine-Assisted Psychotherapy (KAP) – Oral Lozenges & IM Injection, Cannabis-Assisted Therapy, Community Breathwork |
| Conditions Treated | Depression, PTSD, Anxiety, Trauma, Existential Distress, Life Transitions |
| Cost | Contact for pricing – KAP sessions typically 3 hours |
| Insurance | Not accepted – Private pay |
| KAP Available? | Yes – Core offering with preparation and integration sessions |
| Clinical Lead | Daniel McQueen, Founder & Executive Director |
Known For: Established in 2012, the Center for Medicinal Mindfulness is one of the earliest legal psychedelic therapy centers in North America. Founded by Daniel McQueen, the center specializes in ketamine-assisted psychedelic therapy (KAP) alongside cannabis-assisted therapy and community breathwork experiences, offering a uniquely integrative and mindfulness-based approach to psychedelic healing in Boulder.
Why We Picked Them: Center for Medicinal Mindfulness is one of the only clinics in the country offering BOTH Ketamine-Assisted Psychotherapy AND Cannabis-Assisted Psychotherapy under one roof, led by founder Daniel McQueen. Manhattan Drive location serves Boulder, Louisville, and the south Boulder corridor.
Multi-medicine framework is unusual nationally and reflects Colorado’s mature psychedelic-therapy ecosystem.
4. Integrative Psychiatry Center of Boulder
| Review Scores | See psychiatrycenters.com for ratings |
| Location | Boulder, Colorado |
| Address | 5420 Arapahoe Ave, Unit 1, Boulder, CO 80303 |
| Phone | (303) 260-9685 |
| Website | psychiatrycenters.com |
| Conditions Treated | Treatment-Resistant Depression, Anxiety, PTSD, OCD, Chronic Pain |
| Cost | Contact clinic for pricing; Spravato may be covered by insurance |
| KAP Available? | No |
| Clinical Lead | Integrative Psychiatry Centers clinical team |
Known For: Integrative Psychiatry Center of Boulder is part of the Integrative Psychiatry Centers network, offering a blend of conventional psychiatry, ketamine therapy, and complementary approaches including acupuncture and functional medicine. The Boulder location provides IV ketamine infusions and Spravato (esketamine) for treatment-resistant conditions, with psychiatric oversight built into every treatment plan.
Why We Picked Them: Integrative Psychiatry Center of Boulder delivers ketamine within a full integrative psychiatric medical home — medication management, psychotherapy, and ketamine treatment coordinated by the same clinical team rather than referred out.
Continuity-of-care model that pairs ketamine with ongoing psychiatric oversight.
5. Boulder Ketamine
| Review Scores | Not yet rated |
| Location | Boulder, Colorado (North Boulder, 37-acre property) |
| Address | 7372 Olde Stage Road, Boulder, CO 80302 |
| Phone | (303) 502-2442 |
| Website | boulder-ketamine.org |
| Conditions Treated | Depression, Anxiety, PTSD, Trauma |
| Cost | Group format keeps costs accessible; contact for pricing |
| KAP Available? | Yes (group ceremony format) |
| Clinical Lead | Psychiatrist-led team with licensed psychotherapists |
Known For: Boulder Ketamine takes a distinctive ceremonial approach to ketamine-assisted psychotherapy, drawing on ancient group ceremony traditions to amplify the psychological effects of ketamine. Located on 37 acres of pristine land in North Boulder surrounded by thousands of acres of open space, the setting is unlike any other ketamine clinic in Colorado. Treatment begins with a psychiatrist-prescribed ketamine trial followed by six weekly group ceremony sessions guided by licensed psychotherapists.
Why We Picked Them: Boulder Ketamine is one of the longest-operating dedicated ketamine clinics in the Boulder market, with an established track record for IV ketamine infusion therapy serving treatment-resistant depression, anxiety, and chronic pain patients.
Local independent practice with deep community roots and a focused IV ketamine specialty.
Ketamine Treatment FAQs
Does insurance cover ketamine treatment in Boulder?
Plus by APN is in-network with Anthem BCBS, Aetna, TRICARE, and UHC/Optum for its IOP-integrated interventional-psychiatry program (ketamine, Deep TMS, SGB, medication management). Spravato (esketamine) at Integrative Psychiatry Center of Boulder may be covered by insurance. KAP-style programs (Sky Medicine, Center for Medicinal Mindfulness) are typically self-pay.
Is cannabis-assisted psychotherapy available in Boulder?
Yes — Center for Medicinal Mindfulness, founded by Daniel McQueen, offers cannabis-assisted psychotherapy alongside ketamine-assisted psychotherapy (oral lozenges and IM injection). Cannabis-assisted psychotherapy is legal in Colorado but remains rare nationally; Boulder is one of the few U.S. cities where this modality is available within a structured KAP-style framework.
What is Stellate Ganglion Block (SGB), and where can I get it in Boulder?
Stellate Ganglion Block is an interventional-anesthesia procedure used in the treatment of PTSD — a local anesthetic injection near nerve clusters in the neck. Plus by APN integrates SGB with IV ketamine, IM ketamine, Deep TMS, and medication management in an Intensive Outpatient Program. Combining SGB with ketamine modalities and Deep TMS in a structured IOP framework is uncommon outside major academic medical centers.
How much does a 6-session IV ketamine induction series cost in Boulder?
Plus by APN publishes ketamine starting at $340/session, putting a 6-session induction series at $2,040 cash — slightly below the U.S. patient-reported median. KAP at Center for Medicinal Mindfulness runs longer (~3-hour sessions) and typically prices higher. Use the Boulder Ketamine Treatment Cost Calculator above to model your specific scenario.
Are group ketamine sessions available in Boulder?
Yes — Boulder Ketamine offers psychiatrist-led group ketamine sessions designed to keep costs accessible. Group ketamine is rare in mid-tier U.S. metros, where the dosing experience is shared among a small group of patients with therapeutic facilitation. For patients who find group therapy meaningful or want lower-cost peer-supported integration, this is a distinctive Boulder option.
Where do patients commute from for Boulder ketamine care?
Boulder pulls from CU Boulder student and faculty populations, Denver-metro patients seeking KAP/cannabis-assisted depth not available in Denver itself, and Front Range communities (Niwot, Lyons, Longmont, Louisville-Lafayette, Erie). Patients also travel from elsewhere in the Mountain West specifically for cannabis-assisted psychotherapy access.
How does Boulder compare to Denver for ketamine treatment?
Boulder’s ranked clinics emphasize KAP and therapy-frame psychedelic-medicine practice (cannabis-assisted, contemplative, somatic, group) more than Denver’s broader medical-model + Spravato-focused market. Many patients combine the two metros — Spravato access in Denver, KAP and cannabis-assisted work in Boulder. Use each city’s Best-Of guide and Cost Calculator to plan a multi-clinic approach if needed.
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