6 Best Ketamine Clinics in Indianapolis (2026) — Verified & Reviewed
Best Ketamine Clinics in Indianapolis
Indianapolis sits at the I-65/I-70/I-69 ‘Crossroads of America’ — a metro of roughly 2.1 million drawing patients from across central Indiana, with six ranked clinics covering IV ketamine, Spravato, TMS, KAP, and an MD-and-Psychiatric-NP couple-led practice that quietly offers veteran and first-responder discounts. The pricing transparency at one clinic — separate published rates for mood vs. chronic-pain protocols — is the cleanest two-tier indication-split pricing we’ve seen in the Midwest.
3 things to know about Indianapolis ketamine access in 2026
1. Klarity Ketamine Clinic puts IV + Spravato + TMS + Psychiatry + Therapy under one multidisciplinary mental-health team. Klarity Ketamine Clinic offers the full interventional-psychiatry stack — IV ketamine, Spravato (esketamine), TMS, plus integrated psychiatry and therapy — under a multidisciplinary mental-health team. Most ranked Best-Of clinics in the Midwest offer one or two modalities; having all four FDA-approved or mainstream interventional pathways plus integrated therapy under one roof is uncommon outside major academic medical centers.
2. Complete Ketamine Solutions publishes the cleanest two-tier mood-vs-pain pricing in our Midwest coverage. Complete Ketamine Solutions publishes $2,400 for a mood ketamine series and $3,000 for a chronic-pain protocol — split by indication, with financing available. Two-tier published pricing by indication (mood vs. pain) is rare nationally; most clinics either don’t publish prices or publish a single rate. For patients with co-occurring depression and chronic pain trying to model their actual cost up front, this transparency is genuinely useful.
3. AlphaOmega Wellness is led by a husband-and-wife MD + Psychiatric NP team — and quietly offers veteran and first-responder discounts. Dr. Dee Bonney, MD and Megan Bonney, Psychiatric NP run AlphaOmega Wellness as a couple-led clinical practice — combining MD authority with PMHNP psychiatric prescribing depth in close clinical partnership. The practice also offers veteran and first-responder discounts, a meaningful detail in a state with significant military and emergency-services populations.
Indianapolis Ketamine Access Snapshot
- Verified ranked clinics in metro: 6 across Indianapolis — solid modality breadth for the Crossroads of America
- Spravato REMS-certified providers in metro: 1 verified Spravato provider in the ranked list (Klarity Ketamine Clinic — full IV+Spravato+TMS stack)
- Modality mix: IV ketamine infusions, Spravato (esketamine), TMS, ketamine-assisted psychotherapy (KAP), psychiatric medication management, talk therapy, IV vitamin therapy
- Complete Ketamine Solutions published pricing: Mood series $2,400; Pain series $3,000 — cleanest two-tier indication-split pricing in our Midwest coverage
- AlphaOmega Wellness: veteran and first-responder discounts — couple-led MD + Psychiatric NP practice (Dr. Dee Bonney + Megan Bonney)
- National benchmark: Median patient-reported IV ketamine session cost is $350; Indianapolis pricing falls within the U.S. range
- KAP-dedicated practice: Red Maple Wellness focuses on KAP with licensed therapists — therapy-frame integration option in the ranked list
- Regional draw: Indianapolis pulls from across central Indiana — Carmel, Fishers, Greenwood, Bloomington, Lafayette, Anderson — and as far as Terre Haute and Muncie when modality depth is the priority
Behind this data: How we built this: HealingMaps’ verified Indianapolis clinic listings (cross-referenced with clinic-published pricing pages), FDA Spravato REMS provider data, CDC BRFSS Indiana mental-health prevalence, U.S. Census ACS for Marion County, and HealingMaps’ national IV ketamine pricing scrape (n=65 clinics with confirmed per-session rates).
What this means for you: Indianapolis offers Midwest patients real modality breadth — full IV+Spravato+TMS at Klarity, transparent indication-split pain/mood pricing at Complete, couple-led MD+PMHNP at AlphaOmega, and KAP at Red Maple. The practical decision usually turns on (1) modality preference, (2) co-occurring condition (mood vs. pain), and (3) whether you qualify for veteran/first-responder discounts at AlphaOmega. Use the calculator below to model your scenario.
Indianapolis, Indiana Ketamine Treatment Cost Calculator
How Much Will Ketamine Therapy Cost?
Indianapolis Ketamine Clinics At-a-Glance
| Clinic | Modalities | Clinical Lead | Insurance | Per-Session Cost |
|---|---|---|---|---|
| Klarity Ketamine Clinic | IV + Spravato + TMS + Psychiatry + Therapy | Multidisciplinary mental health team | Contact for details | Contact for pricing |
| AlphaOmega Wellness | IV Ketamine Infusions | Dr. Dee Bonney, MD; Megan Bonney, PMHNP (couple-led) | Contact for details | Veteran/first-responder discounts available |
| Hoosier Ketamine & Wellness | IV Ketamine + Vitamin Infusions | Experienced ketamine therapy providers | Contact for details | Contact for pricing |
| Complete Ketamine Solutions | IV Ketamine Infusions | Multidisciplinary medical team | Financing available | Mood: $2,400 · Pain: $3,000 |
| Axon Health Associates | Ketamine Therapy | Mental health specialists | Contact for details | Contact for pricing |
| Red Maple Wellness | Ketamine-Assisted Psychotherapy (KAP) | Licensed KAP therapists | Contact for details | Contact for pricing |
1. Klarity Ketamine Clinic
| Review Scores | Yelp rated (Feb 2026) · 2 locations |
| Location | Castleton & Greenwood, IN |
| Address | 8123 Castleton Rd, Indianapolis, IN (Castleton) |
| Phone | Contact via website |
| Website | getklarity.com |
| Treatments | IV Ketamine, Spravato, TMS, Psychiatry, Therapy |
| Conditions Treated | Depression, Anxiety, PTSD |
| Cost | Contact for pricing |
| Insurance | Contact for details |
| KAP Available? | No (psychiatry and therapy available separately) |
| Clinical Team | Multidisciplinary mental health team |
Known For: Indianapolis’s most comprehensive mental health practice offering ketamine, Spravato, TMS, psychiatry, and therapy across two convenient locations in Castleton and Greenwood.
Why We Picked Them: Klarity offers the broadest range of mental health services of any Indianapolis ketamine provider. Having IV ketamine, Spravato, TMS, psychiatry, and therapy all under one roof means the team can create multi-modal treatment plans. Two locations cover both north and south Indianapolis.
Extended hours (Mon-Fri 8am-6:30pm Castleton) provide scheduling flexibility.
“Klarity’s combination of ketamine, TMS, and psychiatric care gave my treatment team the flexibility to find the right combination for me.”
2. AlphaOmega Wellness
| Review Scores | 1,000+ infusions · 70% success rate |
| Location | Greenwood, IN |
| Phone | (317) 300-4091 |
| Website | alphaomegawellness.com |
| Treatments | IV Ketamine Infusions |
| Conditions Treated | Treatment-Resistant Depression, Anxiety, PTSD |
| Cost | Contact for pricing; veteran/first responder discounts |
| Insurance | Contact for details |
| KAP Available? | No |
| Clinical Lead | Dr. Dee Bonney, MD & Megan Bonney, Psychiatric NP |
| Consultation | Free consultation available |
Known For: Physician-led practice founded by Dr. Dee Bonney and Psychiatric NP Megan Bonney — 1,000+ infusions, 70% success rate, and special pricing for veterans and first responders.
Why We Picked Them: The husband-and-wife physician team brings both medical and psychiatric expertise. Their 70% success rate across 1,000+ infusions demonstrates consistent outcomes, and veteran/first responder discounts reflect a commitment to those who serve.
Private infusion suites in Greenwood provide a comfortable experience.
“Dr. Dee and Megan are incredible. The treatment was transformative — it restored clarity and emotional well-being that I thought was gone forever.”
3. Hoosier Ketamine & Wellness
| Review Scores | Yelp rated · Hundreds of patients helped since 2021 |
| Location | Indianapolis, IN (Castleton area) |
| Address | 6801 Lake Plaza Dr, Suite B-209, Indianapolis, IN 46220 |
| Phone | (463) 466-7437 |
| Website | hoosierketamine.com |
| Treatments | IV Ketamine Infusions, Vitamin Infusions |
| Conditions Treated | Depression, Anxiety, PTSD, OCD, Suicidal Ideation |
| Cost | Contact for pricing |
| Insurance | Contact for details |
| KAP Available? | No |
| Clinical Team | Experienced ketamine therapy providers |
Known For: Indianapolis’s dedicated ketamine practice with customized infusions — hundreds of patients helped since founding in December 2021.
Why We Picked Them: Hoosier Ketamine focuses exclusively on ketamine therapy, customizing each infusion to the patient’s specific needs. Their Castleton location is centrally positioned, and the team’s compassionate care earns consistently positive reviews.
Their focus on suicidal ideation alongside standard mood disorders shows a willingness to treat the most acute cases.
“Hoosier Ketamine helped me break free from years of treatment-resistant depression. The team is caring, compassionate, and truly knowledgeable.”
4. Complete Ketamine Solutions
| Review Scores | 6,000+ infusions nationally · Transparent pricing |
| Location | Indianapolis, IN |
| Website | completeketaminesolutions.com |
| Treatments | IV Ketamine Infusions |
| Conditions Treated | Depression, Anxiety, PTSD, Chronic Pain, OCD, Bipolar Disorder |
| Cost | Mood series: $2,400 · Pain series: $3,000 |
| Insurance | Contact for details; financing available |
| KAP Available? | No |
| Phone | Contact via website |
| Clinical Team | Multidisciplinary medical team |
| Consultation | Free consultation |
Known For: National practice with 6,000+ infusions and transparent pricing — $2,400 mood series / $3,000 pain series with no hidden fees.
Why We Picked Them: Complete Ketamine Solutions brings nationally refined protocols and clear pricing to Indianapolis. Serving Carmel, Fishers, Greenwood, and surrounding communities, their multi-city experience translates to deep institutional knowledge.
Transparent pricing removes the uncertainty that many patients face when exploring ketamine therapy.
“CKS’s transparent pricing and national experience gave me confidence. The Indianapolis team was professional and caring throughout.”
5. Axon Health Associates
| Review Scores | Established Indianapolis practice |
| Location | Indianapolis, IN |
| Treatments | Ketamine Therapy |
| Conditions Treated | Depression, Anxiety, PTSD |
| Phone | Contact via website |
| Website | Contact for details |
| KAP Available? | Contact for details |
| Cost | Contact for pricing |
| Insurance | Contact for details |
| Consultation | Contact for appointment |
| Clinical Team | Mental health specialists |
Known For: Established Indianapolis mental health practice offering ketamine therapy alongside comprehensive psychiatric services.
Why We Picked Them: Axon Health Associates (formerly Indy Advanced Therapeutics) brings established psychiatric expertise to ketamine therapy in Indianapolis. Their comprehensive mental health approach means patients receive proper assessment alongside treatment.
The practice’s longevity in the Indianapolis market reflects sustained quality of care.
“Axon Health’s psychiatric expertise made me confident that my ketamine treatment was properly integrated into my overall mental health care.”
6. Red Maple Wellness
| Review Scores | Specialized KAP practice · Spa-like setting |
| Location | Noblesville, IN (serves Indianapolis, Fishers, Carmel) |
| Website | redmaplewellness.com |
| Treatments | Ketamine-Assisted Psychotherapy (KAP) |
| Conditions Treated | Trauma, Anxiety, Depression, Negative Self-Worth |
| Cost | Contact for pricing |
| Insurance | Contact for details |
| KAP Available? | Yes — core offering (intake + dosing + integration) |
| Phone | Contact via website |
| Clinical Team | Licensed KAP therapists |
| Consultation | Contact for appointment |
Known For: Indianapolis’s only dedicated KAP practice — structured program with intake, two 2-hour dosing sessions, and two integration sessions in a spa-like setting.
Why We Picked Them: Red Maple Wellness is the only dedicated KAP practice in the Indianapolis metro. Their structured program provides the full therapeutic arc that research shows produces more lasting results than ketamine alone. The spa-like environment creates a comfortable setting for deep work.
Serves central Indiana including Indianapolis, Fishers, Noblesville, and Carmel.
“Red Maple’s KAP program was transformative. The integration sessions were just as important as the ketamine itself.”
Ketamine Treatment FAQs
Does insurance cover ketamine treatment in Indianapolis?
Spravato (esketamine) is available at Klarity Ketamine Clinic with insurance coverage variable by plan. IV ketamine is generally self-pay across the ranked Indianapolis clinics. Complete Ketamine Solutions offers financing on its published $2,400 mood and $3,000 pain protocols. Verify each clinic’s specific in-network status at intake.
How much does a 6-session IV ketamine induction series cost in Indianapolis?
Complete Ketamine Solutions publishes $2,400 for a mood series and $3,000 for a chronic-pain protocol. Two-tier published pricing by indication (mood vs. pain) is rare nationally; most clinics quote on request. Use the Indianapolis Ketamine Treatment Cost Calculator above to model your scenario.
Are veteran or first-responder discounts available in Indianapolis?
Yes — AlphaOmega Wellness, run by Dr. Dee Bonney, MD and Megan Bonney, PMHNP (a husband-and-wife clinical team), offers veteran and first-responder discounts. In a state with significant military and emergency-services populations, this is a meaningful access detail.
Can I get full IV+Spravato+TMS+therapy at one Indianapolis clinic?
Yes — Klarity Ketamine Clinic offers IV ketamine, Spravato (esketamine), TMS, integrated psychiatry, and therapy under a multidisciplinary mental-health team. Most ranked Best-Of clinics in the Midwest offer one or two modalities; having all four interventional pathways plus integrated therapy under one roof is uncommon outside major academic medical centers.
Does Indianapolis have a ketamine-assisted psychotherapy (KAP) program?
Yes — Red Maple Wellness focuses on KAP with licensed therapists. KAP integrates the medication experience with licensed-therapist support, designed for patients seeking the therapy-frame approach rather than medical-model IV ketamine.
Where do patients commute from for Indianapolis ketamine care?
Indianapolis is the central-Indiana interventional-psychiatry hub. Patients commute from Carmel, Fishers, Greenwood, Bloomington, Lafayette, Anderson, and as far as Terre Haute and Muncie. For Fort Wayne-area patients, Fort Wayne has its own ranked list; for Louisville-area patients, Louisville does too.
What’s the difference between mood and pain ketamine protocols?
Mood ketamine protocols are typically lower-dose, faster-infusion (40 minutes) sessions targeting depression, anxiety, PTSD. Pain protocols are higher-dose, longer-infusion (sometimes hours) sessions targeting CRPS, neuropathic pain, fibromyalgia. Complete Ketamine Solutions publishes separate $2,400 mood vs. $3,000 pain series, reflecting the different protocol-design and clinical-time requirements.
Explore More: Best Ketamine Clinics by City
Looking for ketamine clinics in another city? Browse our full series of verified clinic guides across the United States and Canada.
